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Latest recommendations
| Id | Title * | Authors * | Abstract * | Picture | Thematic fields * ▲ | Recommender | Reviewers | Submission date | |
|---|---|---|---|---|---|---|---|---|---|
25 Jun 2023
STAGE 1
Cortical plasticity of the tactile mirror system in borderline personality disorderIs borderline personality disorder linked to impairment of the tactile mirror system?Recommended by Chris Chambers based on reviews by Zoltan Dienes and 2 anonymous reviewers
Borderline personality disorder (BPD) is a mental illness affecting ~1 in 100 people (Ellison et al., 2018), characterised by emotional dysregulation, impulsivity, a distorted sense of self, and a long-term pattern of unstable interpersonal relationships. Among this heterogenous range of symptoms is difficulty in the cognitive dimension of empathy, in particular understanding the perspectives of others, which in turn has been suggested to rely on the mirror neuron system, both in the motor and somatosensory domains. The integrity of the mirror system has therefore been a focus for understanding the possible causes or consequences of the disorder, with preliminary studies pointing to hypoactivity of neuronal areas associated with the mirror system in BPD (Mier et al., 2013).
In the current study, Zazio et al. (2023) will use crossmodal paired associative stimulation (cm-PAS) in which an image of a hand being touched is repeatedly paired with transcranial magnetic stimulation (TMS) of the primary somatosensory cortex (S1) to test the hypothesis that BPD is associated with a specific deficit in the tactile mirror system. In healthy controls, the close temporal coupling (20ms) between the visual depiction of tactile stimulation and TMS of S1 is expected boost tactile acuity and elevate the performance cost of incongruence in a task that manipulates visuo-tactile spatial congruity (VTSC) – effects that are thought to reflect the fidelity of the tactile mirror system.
In BPD patients, however, the authors make the crucial prediction that impairment of the tactile mirror system (if present) will lead to a reduced (or even non-existent) effect of cm-PAS on tactile acuity and VTSC task performance compared to healthy controls. To help ensure a severe test of this hypothesis, the design includes a variety of controls, including an attention check, control cm-PAS in which the inter-stimulus interval is increased to 100ms to break the close temporal coupling between visual stimulation and TMS, and a positive control to confirm that active cm-PAS (compared to control cm-PAS) produces the expected boost in tactile acuity in healthy controls.
The Stage 1 manuscript was evaluated over three rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/sqnwd
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Ellison, W. D., Rosenstein, L. K., Morgan, T. A., & Zimmerman, M. (2018). Community and clinical epidemiology of borderline personality disorder. Psychiatric Clinics, 41, 561-573. https://doi.org/10.1016/j.psc.2018.07.008
2. Mier, D., Lis, S., Esslinger, C., Sauer, C., Hagenhoff, M., Ulferts, J., Gallhofer, B. & Kirsch, P. (2013). Neuronal correlates of social cognition in borderline personality disorder. Social Cognitive and Affective Neuroscience, 8, 531-537. https://doi.org/10.1093/scan/nss028 2. Zazio, A., Guidali, G., Rossi, R., Bolognini, N. & Bortoletto, A. (2023). Cortical plasticity of the tactile mirror system in borderline personality disorder, in principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/sqnwd
| Cortical plasticity of the tactile mirror system in borderline personality disorder | Agnese Zazio, Giacomo Guidali, Roberta Rossi, Nadia Bolognini, Marta Bortoletto | <p>People with borderline personality disorder (BPD) show alterations in empathic abilities, which may involve automatic simulation processes relying on mirror-like mechanisms in the somatosensory domain. In the tactile mirror system, the observat... | Life Sciences, Social sciences | Chris Chambers | 2023-01-05 21:50:15 | |||
18 May 2023
STAGE 1
A multilab investigation into the N2pc as an indicator of attentional selectivity: Direct replication of Eimer (1996)Is the N2pc a correlate of attentional selection? An #EEGManyLabs multi-lab registered replication of Eimer (1996)Recommended by Maxine Sherman based on reviews by Reny Baykova and Clayton Hickey
The N2pc is a lateralised ERP component that is often interpreted as a marker of attentional allocation, so much so that it is frequently used a tool in the attention literature for inferring that a stimulus was attentionally processed. This interpretation of N2pc can be traced back to the seminal work of Eimer (1996), which has been conceptually replicated many times but has never been replicated directly.
This registered direct replication by Constant et al. (2023) forms part of a larger series of large-scale, multi-lab replications of highly influential EEG papers by the #EEGManyLabs project (Pavlov et al., 2021). Seven labs (with the potential for more to sign up later), will conduct high-powered replications of the critical Experiment 2 of Eimer (1996), where in the crucial conditions, participants discriminate a target letter (M vs W) or colour (blue vs green) in the presence of a distractor. Using four preprocessing pipelines, including the original, the authors will test whether the N2pc is observed over parieto-occipital electrodes contralateral to target presentation.
The Stage 1 manuscript was evaluated over one round of in-depth review and one additional round of minor corrections. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/dw68r
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA (so-called “primary RR”)
List of eligible PCI RR-friendly journals:
References
1. Constant, M., Mandal, A., Asanowicz, D., Yamaguchi, M., Gillmeister, H., Kerzel, D., Luque, D., Pesciarelli, F., Fehr, T., Mushtaq, F., Pavlov, Y. G. & Liesefeld, H. R. (2023). A multilab investigation into the N2pc as an indicator of attentional selectivity: Direct replication of Eimer (1996), in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/dw68r
2. Eimer, M. (1996). The N2pc component as an indicator of attentional selectivity. Electroencephalography and Clinical Neurophysiology, 99, 225-234. https://doi.org/10.1016/0013-4694(96)95711-9
3. Pavlov, Y. G., Adamian, N., Appelhoff, S., Arvaneh, M., Benwell, C. S., Beste, C., ... & Mushtaq, F. (2021). #EEGManyLabs: Investigating the replicability of influential EEG experiments. Cortex, 144, 213-229. https://doi.org/10.1016/j.cortex.2021.03.013
| A multilab investigation into the N2pc as an indicator of attentional selectivity: Direct replication of Eimer (1996) | Martin Constant, Ananya Mandal, Dariusz Asanowicz, Motonori Yamaguchi, Helge Gillmeister, Dirk Kerzel, David Luque, Francesca Pesciarelli, Thorsten Fehr, Faisal Mushtaq, Yuri G. Pavlov, Heinrich R. Liesefeld | <p>The N2pc is widely employed as an electrophysiological marker of an attention allocation. This interpretation was in no small part driven by the observation of an N2pc elicited by an isolated relevant target object, which was reported as Experi... | Life Sciences, Social sciences | Maxine Sherman | 2023-02-24 11:41:52 | |||
Evaluating the Pedagogical Effectiveness of Study Preregistration in the Undergraduate DissertationIncorporating open research practices into the undergraduate curriculum increases understanding of such practicesRecommended by Corina Logan based on reviews by Kelsey McCune, Neil Lewis, Jr., Lisa Spitzer and 1 anonymous reviewer
In a time when open research practices are becoming more widely used to combat questionable research practices (QRPs) in academia, this Registered Report by Pownall and colleagues (2023) empirically investigated the practice of preregistering study plans, which allows us to better understand to what degree such practices increase awareness of QRPs and whether experience with preregistration helps reduce engagement in QRPs. This investigation is timely because results from these kinds of studies are only recently becoming available and the conclusions are providing evidence that open research practices can improve research quality and reliability (e.g., Soderberg et al. 2021, Chambers & Tzavella 2022). The authors crucially focused on the effect of preregistering the undergraduate senior thesis (of psychology students in the UK), which is a key stage in the development of an academic.
Pownall and colleagues found that preregistration did not affect attitudes toward QRPs, but it did improve student understanding of open research practices. Using exploratory analyses, they additionally found that those who preregistered were those students who reported that they had more opportunity, motivation, and greater capability. This shows how important it is to incorporate the teaching of open research practices such that students can increase their capability, motivation, and opportunity to pursue such practices, whether it is preregistration or other practices that are better known to reduce QRPs (such as registered reports; Krypotos et al. 2022).
After four rounds of review and revisions, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
URL to the preregistered Stage 1 protocol: https://osf.io/9hjbw
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
List of eligible PCI RR-friendly journals:
References
1. Chambers C. D. & Tzavella, L. (2022). The past, present, and future of Registered Reports. Nature Human Behaviour, 6, 29-42. https://doi.org/10.1038/s41562-021-01193-7
2. Krypotos, A. M., Mertens, G., Klugkist, I., & Engelhard, I. M. (2022). Preregistration: Definition, advantages, disadvantages, and how it can help against questionable research practices. In Avoiding Questionable Research Practices in Applied Psychology (pp. 343-357). Cham: Springer International Publishing.
3. Pownall, M., Pennington, C. R., Norris, E., Juanchich, M., Smaile, D., Russell, S., Gooch, D., Rhys Evans, T., Persson, S., Mak, M. H. C., Tzavella, L., Monk, R., Gough, T., Benwell, C. S. Y., Elsherif, M., Farran, E., Gallagher-Mitchell, T., Kendrick, L. T., Bahnmueller, J., Nordmann, E., Zaneva, M., Gilligan-Lee, K., Bazhydai, M., Jones, A., Sedgmond, J., Holzleitner, I., Reynolds, J., Moss, J., Farrelly, D., Parker, A. J. & Clark, K. (2023). Evaluating the pedagogical effectiveness of study preregistration in the undergraduate dissertation [Stage 2 Registered Report], acceptance of Version 4 by Peer Community in Registered Reports. https://psyarxiv.com/xg2ah
4. Soderberg C. K., Errington T. M., Schiavone S. R., Bottesini J., Thorn F. S., Vazire S., Esterling K. M. & Nosek B. A. (2021) Initial evidence of research quality of registered reports compared with the standard publishing model. Nature Human Behaviour, 5, 990–997. https://doi.org/10.1038/s41562-021-01142-4
| Evaluating the Pedagogical Effectiveness of Study Preregistration in the Undergraduate Dissertation | Madeleine Pownall, Charlotte R. Pennington, Emma Norris, Marie Juanchich, David Smaile, Sophie Russell, Debbie Gooch, Thomas Rhys Evans, Sofia Persson, Matthew HC Mak, Loukia Tzavella, Rebecca Monk, Thomas Gough, Christopher SY Benwell, Mahmoud El... | <p>Research shows that questionable research practices (QRPs) are present in undergraduate final-year dissertation projects. One entry-level Open Science practice proposed to mitigate QRPs is ‘study preregistration’, through which researchers outl... | Life Sciences, Social sciences | Corina Logan | 2023-03-25 11:38:54 | |||
09 Jul 2024
STAGE 1
Test-Retest Reliability in Functional Magnetic Resonance Imaging: Impact of Analytical Decisions on Individual and Group Estimates in the Monetary Incentive Delay TaskExploring determinants of test-retest reliabilty in fMRIRecommended by Dorothy Bishop based on reviews by Xiangzhen Kong and 2 anonymous reviewers
Functional magnetic resonance imaging (fMRI) has been used to explore brain-behaviour relationships for many years, with proliferation of a wide range of sophisticated analytic procedures. However, rather scant attention has been paid to the reliability of findings. Concerns have been growing following failures to replicate findings in some fields, but it is hard to know how far this is a consequence of underpowered studies, flexible analytic pipelines, or variability within and between participants.
Demidenko et al. (2023) plan a study that will be a major step forward in addressing these issues. They take advantage of the availability of three existing datasets, the Adolescent Brain Cognitive Development (ABCD) study, the Michigan Longitudinal Study, and the Adolescent Risk Behavior Study, which all included a version of the Monetary Incentive Delay task measured in two sessions. This gives ample data for a multiverse analysis, which will consider how within-subject and between-subject variance varies according to four analytic factors: smoothing (5 levels), motion correction (6 levels), task modelling (3 levels) and task contrasts (4 levels). They will also consider how sample size affects estimates of reliability. This will involve a substantial amount of analysis.
The study is essentially focused on estimation, although specific predictions are presented regarding the combinations of factors expected to give optimal reliability. The outcome will be a multiverse of results which will allow us to see how different pipeline decisions for this task affect reliability. In many ways, null results – finding that at least some factors have little effect on reliability – would be a positive finding for the field, as it would mean that we could be more relaxed when selecting an analytic pathway. A more likely outcome, however, is that analytic decisions will affect reliability, and this information can then guide future studies and help develop best practice guidelines. As one reviewer noted, we can’t assume that results from this analysis will generalise to other tasks, but this analysis with a widely-used task is an important step towards better and more consistent methods in fMRI.
The researchers present a fully worked out plan of action, with supporting scripts that have been developed in pilot testing. The Stage 1 manuscript received in-depth evaluation from three expert reviewers and the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/nqgeh
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet sufficiently observed the key variables within the data to be able to answer the research questions AND they have taken additional steps to maximise bias control and rigour.
List of eligible PCI RR-friendly journals:
References 1. Demidenko, M. I., Mumford, J. A., & Poldrack, R. A. (2023). Test-Retest Reliability in Functional Magnetic Resonance Imaging: Impact of Analytical Decisions on Individual and Group Estimates in the Monetary Incentive Delay Task. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/nqgeh | Test-Retest Reliability in Functional Magnetic Resonance Imaging: Impact of Analytical Decisions on Individual and Group Estimates in the Monetary Incentive Delay Task | Michael I. Demidenko, Jeanette A. Mumford, Russell A. Poldrack | <p>Empirical studies reporting low test-retest reliability of individual neural estimates in functional magnetic resonance imaging (fMRI) data have resurrected interest among cognitive neuroscientists in methods that may improve reliability in fMR... | Life Sciences, Social sciences | Dorothy Bishop | 2023-04-17 22:27:54 | |||
22 Oct 2023
STAGE 1
Michotte's research on perceptual impressions of causality: a pre-registered replication studyGaining confidence in Michotte’s classic studies on the perception of causalityRecommended by Moin Syed based on reviews by Maxine Sherman and 1 anonymous reviewer
Making causal judgements are part of everyday life, whether seeking to understand the action of complex humans or the relations between inanimate objects in our environments. Albert Michotte’s (1963) classic book, The perception of causality, contained an extensive report of experiments demonstrating not only that observers perceive causality of inanimate shapes, but do so in manifold ways, creating different “causal impressions.” This work has been highly influential across psychology and neuroscience.
In the current study, White (2023) proposes a series of experiments to replicate and extend Michotte’s work. Despite the fact that this research is foundational to current work on perception and understanding of causal relations, it has never been subjected to rigorous replication. Moreover, like many research studies from that era, Michotte was sparse on details about methodology and did not rely on statistical analysis. White has proposed an ambitious set of 14 experiments that directly replicate and, in some cases, extend Michotte’s experiments.
The Stage 1 manuscript was evaluated over three rounds of in-depth review, the first two rounds consisting of detailed comments from two reviewers and the third round consisting of a close read by the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and was therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/5jx8f (under temporary private embargo)
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI-RR-friendly journals:
References
1. Michotte, A. (1963). The perception of causality (T. R. Miles & E. Miles, trans.). London: Methuen. (English translation of Michotte, 1954).
2. White, P. A. (2023). Michotte's research on perceptual impressions of causality: A registered replication study. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/5jx8f
| Michotte's research on perceptual impressions of causality: a pre-registered replication study | Peter A. White | <p> Michotte (1946/1954/1963) showed that visual impressions of causality can occur in perception of simple animations of moving geometrical objects. In the launching effect, one object is perceived as maki... | Life Sciences, Social sciences | Moin Syed | 2023-05-03 13:04:00 | |||
11 Sep 2023
STAGE 1
Finding the right words to evaluate research: An empirical appraisal of eLife’s assessment vocabularyUnderstanding the validity of standardised language in research evaluationRecommended by Sarahanne Miranda Field and Chris Chambers based on reviews by Chris Hartgerink (they/them), Veli-Matti Karhulahti, Štěpán Bahník and Ross Mounce
In 2023, the journal eLife ended the practice of making binary accept/reject decisions following peer review, instead sharing peer review reports (for manuscripts that are peer-reviewed) and brief “eLife assessments” representing the consensus opinions of editors and peer reviewers. As part of these assessments, the journal draws language from a "common vocabulary" to linguistically rank the significance of findings and strength of empirical support for the article's conclusions. In particular, the significance of findings is described using an ordinal scale of terms from "landmark" → "fundamental" → "important" → "valuable" → "useful", while the strength of support is ranked across six descending levels from "exceptional" down to "inadequate".
In the current study, Hardwicke et al. (2023) question the validity of this taxonomy, noting a range of linguistic ambiguities and counterintuitive characteristics that may undermine the communication of research evaluations to readers. Given the centrality of this common vocabulary to the journal's policy, the authors propose a study to explore whether the language used in the eLife assessments will be interpreted as intended by readers. Using a repeated-measures experimental design, they will tackle three aims: first, to understand the extent to which people share similar interpretations of phrases used to describe scientific research; second, to reveal the extent to which people’s implicit ranking of phrases used to describe scientific research aligns with each other and with the intended ranking; and third, to test whether phrases used to describe scientific research have overlapping interpretations. The proposed study has the potential to make a useful contribution to metascience, as well as being a valuable source of information for other journals potentially interested in following the novel path made by eLife.
The Stage 1 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/mkbtp
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Hardwicke, T. E., Schiavone, S., Clarke, B. & Vazire, S. (2023). Finding the right words to evaluate research: An empirical appraisal of eLife’s assessment vocabulary. In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/mkbtp | Finding the right words to evaluate research: An empirical appraisal of eLife’s assessment vocabulary | Tom E. Hardwicke, Sarah Schiavone, Beth Clarke, Simine Vazire | <p>The journal eLife recently announced that it would abandon binary ‘accept/reject’ decisions and instead focus on sharing both peer review reports and short “eLife assessments” representing the consensus opinions of editors and peer reviewers. F... | Life Sciences, Social sciences | Sarahanne Miranda Field | 2023-06-16 12:11:14 | |||
The importance of conceptual knowledge when becoming familiar with faces during naturalistic viewingA registered test of the role of contextual information in perceptual learning of facesRecommended by Robert McIntosh based on reviews by Haiyang Jin
When we familiarise with new faces over repeated exposures, it is generally in situations that have meaning for us. Seeing a face more often tends to go along with learning more about the person, and their likely contexts and actions. In this Registered Report, Noad and Andrews (2024) tested whether meaningful context during exposure improves the consolidation of faces into long-term memory. Participants were shown video clips from the TV series Life on Mars, either in their original chronological sequence, which provides meaningful context, or in a scrambled sequence. It was expected that the original sequence would provide a better conceptual understanding, and this was confirmed by free recall and structured question tests. Face recognition memory was tested with images of the actor from the original clips (‘in show’) and the same actor from another show (‘out-of-show’), to test whether memory was modulated by the similarity of appearance to that at encoding. Face recognition was tested immediately after exposure and after four weeks, to allow time for consolidation. As expected, recognition memory was better for participants in the meaningful context condition, and for in-show faces. However, meaningful context did not lead to less forgetting of the faces at the follow up test, even for in-show faces, which did not support the original predictions. An exploratory analysis found that a metric of overlap between pairs of participants’ conceptual understanding was related to overlap in the set of faces they recognised. This relationship was stronger after four weeks, which suggests increased interaction of conceptual knowledge and face recognition after consolidation.
The Stage 2 manuscript was assessed over two rounds of review, and the recommender judged that the manuscript met the Stage 2 criteria for recommendation.
URL to the preregistered Stage 1 protocol: https://osf.io/8wp6f
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Noad, K. & Andrews, T. J. (2024). The importance of conceptual knowledge when becoming familiar with faces during naturalistic viewing [Stage 2]. Acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/thgrz | The importance of conceptual knowledge when becoming familiar with faces during naturalistic viewing | Kira N. Noad and Timothy J. Andrews | <p>Although the ability to recognise familiar faces is a critical part of everyday life, the process by which a face becomes familiar in the real world is not fully understood. Previous research has focussed on the importance of perceptual experie... | Life Sciences, Social sciences | Robert McIntosh | 2024-01-17 16:00:17 | |||
Impact of analytic decisions on test-retest reliability of individual and group estimates in functional magnetic resonance imaging: a multiverse analysis using the monetary incentive delay taskExploring determinants of test-retest reliability in fMRI: a study with the Monetary Incentive Delay TaskRecommended by Dorothy Bishop based on reviews by Xiangzhen Kong and 1 anonymous reviewer
Functional magnetic resonance imaging has been used to explore brain-behaviour relationships for many years, with proliferation of a wide range of sophisticated analytic procedures. However, rather scant attention has been paid to the reliability of findings. Concerns have been growing failures to replicate findings in some fields, but it is hard to know how far this is a consequence of underpowered studies, flexible analytic pipelines, or variability within and between participants. Demidenko et al. (2024) took advantage of the availability of three existing datasets, including the Adolescent Brain Cognitive Development (ABCD) study, the Michigan Longitudinal Study, and the Adolescent Risk Behavior Study, which all included a version of the Monetary Incentive Delay task measured in two sessions. These were entered into a multiverse analysis, which considered how within-subject and between-subject variance varies according to four analytic factors: smoothing (5 levels), motion correction (6 levels), task modelling (3 levels) and task contrasts (4 levels). They also considered how sample size affects estimates of reliability. The results have important implications for the those using fMRI with the Monetary Incentive Delay Task, and also raise questions more broadly about use of fMRI indices to study individual differences. Motion correction had relatively little impact on the ICC, and the effect size of the smoothing kernel was modest. Larger impacts on reliability were associated with choice of contrast (implicit baseline giving larger effects) and task parameterization. But perhaps the most sobering message from this analysis is that although activation maps from group data were reasonably reliable, the ICC, used as an index of reliability for individual levels of activation, was consistently low. This raises questions about the suitability of the Monetary Incentive Delay Task for studying individual differences. Another point is that reliability estimates become more stable as sample size increases; researchers may want to consider whether the trade-off between cost and gain in precision is justified for sample sizes above 250. I did a quick literature search on Web of Science: at the time of writing the search term ("Monetary Delay Task" AND fMRI) yielded 410 returns, indicating that this is a popular method in cognitive neuroscience. The detailed analyses reported here will repay study for those who are planning further research using this task. The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewer's and recommender's comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation. URL to the preregistered Stage 1 protocol: https://osf.io/nqgeh
Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors prior to IPA, but the authors certify that they had not yet sufficiently observed the key variables within the data to be able to answer the research questions and they took additional steps to maximise bias control and rigour.
List of eligible PCI RR-friendly journals:
References 1. Demidenko, M. I., Mumford, J. A., & Poldrack, R. A. (2024). Impact of analytic decisions on test-retest reliability of individual and group estimates in functional magnetic resonance imaging: a multiverse analysis using the monetary incentive delay task [Stage 2]. Acceptance of Version 5 by Peer Community in Registered Reports. https://www.biorxiv.org/content/10.1101/2024.03.19.585755v4 | Impact of analytic decisions on test-retest reliability of individual and group estimates in functional magnetic resonance imaging: a multiverse analysis using the monetary incentive delay task | Michael I. Demidenko, Jeanette A. Mumford, Russell A. Poldrack | <p>Empirical studies reporting low test-retest reliability of individual blood oxygen-level dependent (BOLD) signal estimates in functional magnetic resonance imaging (fMRI) data have resurrected interest among cognitive neuroscientists in methods... |  | Life Sciences, Social sciences | Dorothy Bishop | 2024-03-21 02:23:30 | ||
13 Jul 2023
STAGE 1
Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered reportNeurocognitive insights on instructed extinction in the context of painRecommended by Chris Chambers based on reviews by Tom Beckers, Gaëtan Mertens and Karita Ojala
Rapid learning in response to pain is a crucial survival mechanism, relying on forming associations between cues in the environment and subsequent pain or injury. Existing evidence suggests that associations between conditioned stimuli (cues) and unconditioned aversive stimuli (such as pain) are learned faster than for appetitive stimuli that signal pain relief. In addition, when the link between a conditioned and unconditioned stimulus is broken (by unpairing them), the extinction of this learning effect is slower for aversive that appetitive stimuli, resulting in a flatter extinction slope. Understanding why extinction slopes are reduced for aversive stimuli is important for advancing theoretical models of learning, and for devising ways of increasing the slope (and thus facilitating extinction learning) could help develop more effective methods of pain relief, particularly in the treatment of chronic pain.
In the current programmatic submission, Busch et al. (2023) will undertake two Registered Reports to test whether a verbal instruction intervention that explicitly informs participants about contingency changes between conditioned and unconditioned stimuli facilitates extinction learning, especially for aversive (painful) stimuli, and how changes in extinction learning relate to neural biomarkers of functional connectivity. In the first Registered Report, they will initially seek to replicate previous findings including faster acquisition of aversive than appetitive conditioned stimuli as well as incomplete extinction of aversive conditioned stimuli without verbal instruction. They will then test how the instruction intervention alters extinction slopes and the completeness of extinction for appetitive and aversive stimuli, using a range of behavioral measures (expectancy and valence ratings) and physiological measures (pupillometry, skin conductance responses). To shed light on the neural correlates of these processes, in the second Registered Report the authors will use functional magnetic resonance imaging (fMRI) to ask firstly how acquisition and extinction of aversive and appetitive conditioned responses are related to resting state brain connectivity within a network that includes ventromedial prefrontal cortex, amygdala, and striatum, and secondly, whether the effectiveness of instruction on extinction learning is associated with differences in resting state connectivity across this network.
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/cj75p (under temporary private embargo)
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Busch, L., Wiech, K., Gamer, M., Knicses, B., Spisak, T., Schmidt, K., & Bingel, U. (2023). Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered report. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/cj75p
| Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered report | Lea Busch, Katja Wiech, Matthias Gamer, Balint Kincses, Tamas Spisak, Katharina Schmidt, Ulrike Bingel | <p>In the context of pain, extinction learning has been shown to be slower or incomplete for aversive compared to appetitive cues (i.e., cues signaling pain exacerbation and pain relief, respectively), potentially due to their higher biological re... | Medical Sciences | Chris Chambers | 2022-10-15 19:45:48 | |||
31 May 2023
STAGE 1
Defacing biases in manual and automated quality assessments of structural MRI with MRIQCThe impact of removing facial features on quality measures of structural MRI scansRecommended by D. Samuel Schwarzkopf based on reviews by Catherine Morgan and Cassandra Gould van Praag
Data sharing is perhaps the most fundamental step for increasing the transparency and reproducibility of scientific research. However, the goals of open science must be tempered by ethical considerations, protecting the privacy and safety of research participants. Bridging this gap causes challenges for many fields, such as human neuroimaging. Brain images, as measured with magnetic resonance imaging (MRI), are unique to the participant and therefore contain identifying information by definition. One way to mitigate the risk to participants arising from public data sharing has been "defacing" the MRI scans, i.e., literally removing the part of the image that contains the face and surrounding tissue, while preserving the brain structure. This procedure however also removes information that is not (or at least minimally) identifiable. It also remains unclear whether defacing the images affects image quality and thus the information necessary for addressing many research questions.
The current study by Provins et al. (2023) seeks to address this question. Leveraging a publicly available "IXI dataset" comprising hundreds of T1-weighted structural MRI scans, they will assess the effect of defacing on manual and automatic estimates of image quality. Specifically, the researchers will compare image quality ratings by experts for a subset of 185 images. They hypothesise that images in which facial features have been removed are typically assigned higher quality ratings. Moreover, using a full data set of 580 images, which have been obtained across three scanning sites, they will also test the impact defacing MRI scans has on automated quality measures obtained with MRIQC software. The results of this study should have important implications for open science policy and for designing the optimal procedures for sharing structural MRI data in an ethical way. For example, if the authors' hypothesis is confirmed, studies relying on MRI quality measures might be better served by a custodianship model where identifiable data is shared under strict conditions, rather than relying on publishing defaced data. More generally, the outcome of this study may have significant legal implications in many jurisdictions.
The Stage 1 manuscript was evaluated at the inital triage stage by the Recommender and PCI:RR team, and another round of in-depth review by two experts. After a detailed response and substantial revisions, the recommender judged the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/qcket (under temporary private embargo)
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question AND they have taken additional steps to maximise bias control and rigour. List of eligible PCI RR-friendly journals:
References
1. Provins, C., Savary, E., Alemán-Gómez, Y., Richiardi, J., Poldrack, R. A., Hagmann, P. & Esteban, O. (2023). Defacing biases in manual and automated quality assessments of structural MRI with MRIQC, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/qcket
| Defacing biases in manual and automated quality assessments of structural MRI with MRIQC | Céline Provins, Yasser Alemán-Gómez, Jonas Richiardi, Russell A. Poldrack, Patric Hagmann, Oscar Esteban | <p>A critical requirement before data-sharing of human neuroimaging is removing facial features to protect individuals’ privacy. However, not only does this process redact identifiable information about individuals, but it also removes non-identif... | Medical Sciences | D. Samuel Schwarzkopf | Cassandra Gould van Praag, Catherine Morgan, Abiola Akinnubi | 2022-11-28 10:59:32 |
