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Latest recommendations
Id | Title * ▼ | Authors * | Abstract * | Picture | Thematic fields * | Recommender | Reviewers | Submission date | |
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11 Sep 2023
STAGE 1
Researcher Predictions of Effect Generalizability Across Global SamplesKathleen Schmidt, Priya Silverstein, & Christopher R. Chartier https://osf.io/ygbr5?view_only=348484e6e86442e5a43e75e0cf9aa310Can psychology researchers predict which effects will generalise across cultures?Recommended by Chris Chambers based on reviews by Michèle Nuijten, Ian Hussey, Jim Grange and Matthias StefanCompared to the wealth of debate surrounding replicability and transparency, relatively little attention has been paid to the issue of generalisability – the extent to which research findings hold across different samples, cultures, and other parameters. Existing research suggests that researchers in psychology are prone to generalisation bias, relying on narrow samples (e.g. drawn predominantly from US or European undergraduate samples) to draw broad conclusions about the mind and behaviour. While recent attempts to address generalisability concerns have been made – such as journals requiring explicit statements acknowledging constraints on generality – addressing this bias at root, and developing truly generalisable methods and results, requires a deeper understanding of how researchers perceive generalisability in the first place.
In the current study, Schmidt et al. (2023) tackle the issue of cross-cultural generalisability using four large-scale international studies that are being conducted as part of the Psychological Science Accelerator (PSA) – a globally distributed network of researchers in psychology that coordinates crowdsourced research projects across six continents. Specifically, participants (who will be PSA research members) will estimate the probability that an expected focal effect will be observed both overall and within regional subsamples of the PSA studies. They will also predict the size of these focal effects overall and by region.
Using this methodology, the authors plan to ask two main questions: first whether researchers can accurately predict the generalisability of psychological phenomena in upcoming studies, and second whether certain researcher characteristics (including various measures of expertise, experience, and demographics) are associated with the accuracy of generalisability predictions. Based on previous evidence that scientists can successfully predict the outcomes of research studies, the authors expect to observe a positive association between predicted and actual outcomes and effect sizes. In secondary analyses, the authors will also test if researchers can predict when variables that capture relevant cultural differences will moderate the focal effects – if so, this would suggest that at least some researchers have a deeper understanding as to why the effects generalise (or not) across cultural contexts.
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/vwqsa (under temporary private embargo)
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Schmidt, K., Silverstein, P. & Chartier, C. R. (2023). Registered Report: Researcher Predictions of Effect Generalizability Across Global Samples. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/vwqsa
| Researcher Predictions of Effect Generalizability Across Global Samples | Kathleen Schmidt, Priya Silverstein, & Christopher R. Chartier | <p>The generalizability of effects is an increasing concern among researchers in psychological science. Traditionally, the field has relied on university samples from Europe and North America to make claims about humans writ large. The proposed re... | Social sciences | Chris Chambers | 2023-02-16 03:49:35 | View | ||
31 May 2024
STAGE 1
Representativeness heuristic in intuitive predictions: Replication Registered Report of problems reviewed in Kahneman and Tversky (1973)Hong Ching (Bruce) Chan, Gilad Feldman https://osf.io/9cqp6The Representativeness Heuristic Revisited: Registered Replication Report of Kahneman and Tversky (1973)Recommended by Rima-Maria Rahal based on reviews by Peter Anthony White, Regis Kakinohana and Naseem Dillman-HassoRevisiting a true classic, this registered replication report addresses Kahneman and Tversky’s (1973) introduction of the representativeness heuristic. The heuristic refers to deviations of judgments from normative evaluations of the evidence when the stimulus fits to a prototype. For instance, when an individual is described by features stereotypically associated with a certain target group (e.g., a person who attends dance training several times a week and has a passion for singing and performing), likelihood judgments that the individual belongs to a target group (K-Pop artists) compared to a non-target group (e.g., accountants) are inflated.
The impact of the original research on the field is clearly immense and long-lasting. All the better that a systematic replication attempt is being undertaken in this registered report, which addresses studies 1 through 7 of Kahneman and Tversky’s classic 1973 paper. Chan and Feldman (2024) propose a well-powered online study, in which all studies from the original article are presented to participants within-subjects. The materials are carefully constructed and closely documented in the accompanying OSF project, where in-depth information on planned data analyses is supported with a simulated dataset. The Stage 1 manuscript was evaluated over three rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA). URL to the preregistered Stage 1 protocol: https://osf.io/er2cq
Level of bias control achieved: Level 6. Data collection commenced during the later part of Stage 1 peer review; however, since no substantive changes to the design were made after this point, the risk of bias due to prior data observation remains zero and the manuscript therefore qualifies for Level 6.
List of eligible PCI RR-friendly journals:
References
1. Chan, H. C. & Feldman, G. (2024). Representativeness heuristic in intuitive predictions: Replication Registered Report of problems reviewed in Kahneman and Tversky (1973). In principle acceptance of Version 5 by Peer Community in Registered Reports. https://osf.io/er2cq 2. Kahneman, D., & Tversky, A. (1973). On the psychology of prediction. Psychological Review, 80(4), 237–251. https://doi.org/10.1037/h0034747
| Representativeness heuristic in intuitive predictions: Replication Registered Report of problems reviewed in Kahneman and Tversky (1973) | Hong Ching (Bruce) Chan, Gilad Feldman | <p>[IMPORTANT: Abstract, method, and results were written using a randomized dataset produced by Qualtrics to simulate what these sections will look like after data collection. These will be updated following the data collection. For the purpose o... | Social sciences | Rima-Maria Rahal | 2023-11-29 15:19:07 | View | ||
22 Jul 2024
STAGE 1
Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”Maha Said, Mustafa Gharib, Samia Zrig, Raphaël Lévy https://osf.io/kf9qe/Replicating, Revising and Reforming: Unpicking the Apparent Nanoparticle Endosomal Escape ParadoxRecommended by Emily Linnane and Yuki Yamada based on reviews by Cecilia Menard-Moyon and Zeljka KrpeticContext
Over the past decade there has been an exponential increase in the number of research papers utlising nanoparticles for biological applications such as intracellular sensing [1, 2], theranostics [3-5] and more recently drug delivery and precision medicine [6, 7]. Despite the success stories, there is a disconnect regarding current dogma on issues such as nanoparticle uptake and trafficking, nanoparticle delivery via the enhanced permeability and retention (EPR) effect, and endosomal escape. Critical re-evaluation of these concepts both conceptually and experimentally is needed for continued advancement in the field.
For this preregistration, Said et al. (2024) focus on nanoparticle intracellular trafficking, specifically endosomal escape [8]. The current consensus in the literature is that nanoparticles enter cells via endocytosis [9, 10] but reportedly just 1-2% of nanoparticles/ nanoparticle probes escape endosomes and enter the cytoplasm [11-13]. There is therefore an apparent paradox over how sensing nanoparticles can detect their intended targets in the cytoplasm if they are trapped within the cell endosomes. To address this fundamental issue of nanoparticle endosomal escape, Lévy and coworkers are carrying out replication studies to thoroughly and transparently replicate the most influential papers in the field of nanoparticle sensing. The aim of these replication studies is twofold: to establish a robust methodology to study endosomal escape of nanoparticles, and to encourage discussions, transparency and a step-change in the field.
Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”
For this replication study, the authors classified papers on the topic of nanoparticle sensing and subsequently ranked them by number of citations. Based on this evaluation they selected a paper by Zhu and colleagues [14] entitled “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions” for their seminal replication study. To determine the reproducibility of the results from Zhu et al., the authors aim to establish the proportion of endosomal escape of the nanoparticles, and to examine the data in a biological context relevant to the application of the probe.
Beyond Replication
The authors plan to replicate the exact conditions reported in the materials and methods section of the selected paper such as nanoparticle probe synthesis of CdSe@C-TPEA nanoparticles, assessment of particle size, stability and reactivity and effect on cells (TEM, pH experiments, fluorescent responsivity to metal ions and cell viability). In addition, Said et al., plan to include further experimental characterisation to complement the existing study by Zhu and colleagues. They will incorporate additional controls and methodology to determine the intracellular location of nanoparticle probes in cells including: quantifying excess fluorescence in the culture medium, live cell imaging analysis, immunofluorescence with endosomal and lysosomal markers, and electron microscopy of cell sections. The authors will also include supplementary viability studies to assess the impact of the nanoparticles on HeLa cells as well as an additional biologically relevant cell line (for use in conjunction with the HeLa cells as per the original paper).
The Stage 1 manuscript underwent two rounds of thorough in-depth review. After considering the detailed responses to the reviewers' comments, the recommenders determined that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
The authors have thoughtfully considered their experimental approach to the replication study, whilst acknowledging any potential limitations. Given that conducting such a replication study is novel in the field of Nanotechnology and there is currently no ‘gold standard’ approach in doing so, the authors have showed thoughtful regard of statistical analysis and unbiased methodology where possible.
Based on current information, this study is the first use of preregistration via Peer Community in Registered Reports and the first formalised replication study in Nanotechnology for Biosciences. The outcomes of this of this study will be significant both scientifically and in the wider context in discussion of the scientific method.
URL to the preregistered Stage 1 protocol: https://osf.io/qbxpf
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly Journals:
References
1. Howes, P. D., Chandrawati, R., & Stevens, M. M. (2014). Colloidal nanoparticles as advanced biological sensors. Science, 346(6205), 1247390. https://doi.org/10.1126/science.1247390
2. Liu, C. G., Han, Y. H., Kankala, R. K., Wang, S. B., & Chen, A. Z. (2020). Subcellular performance of nanoparticles in cancer therapy. International Journal of Nanomedicine, 675-704. https://doi.org/10.2147/IJN.S226186
3. Tang, W., Fan, W., Lau, J., Deng, L., Shen, Z., & Chen, X. (2019). Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics. Chemical Society Reviews, 48(11), 2967-3014. https://doi.org/10.1039/C8CS00805A
4. Yoon, Y. I., Pang, X., Jung, S., Zhang, G., Kong, M., Liu, G., & Chen, X. (2018). Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics. Journal of Materials Chemistry B, 6(20), 3235-3239. https://doi.org/10.1039%2FC8TB00368H
5. Lin, H., Chen, Y., & Shi, J. (2018). Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy. Chemical Society Reviews, 47(6), 1938-1958. https://doi.org/10.1039/C7CS00471K
6. Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021). Lipid nanoparticles for mRNA delivery. Nature Reviews Materials, 6(12), 1078-1094. https://doi.org/10.1038/s41578-021-00358-0
7. Mitchell, M. J., Billingsley, M. M., Haley, R. M., Wechsler, M. E., Peppas, N. A., & Langer, R. (2021). Engineering precision nanoparticles for drug delivery. Nature Reviews Drug Discovery, 20(2), 101-124. https://doi.org/10.1038/s41573-020-0090-8
8. Said, M., Gharib, M., Zrig, S., & Lévy, R. (2024). Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/qbxpf
9. Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., ... & Mahmoudi, M. (2017). Cellular uptake of nanoparticles: Journey inside the cell. Chemical Society Reviews, 46(14), 4218-4244. https://doi.org/10.1039/C6CS00636A
10. de Almeida, M. S., Susnik, E., Drasler, B., Taladriz-Blanco, P., Petri-Fink, A., & Rothen-Rutishauser, B. (2021). Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine. Chemical society reviews, 50(9), 5397-5434. https://doi.org/10.1039/D0CS01127D
11. Smith, S. A., Selby, L. I., Johnston, A. P., & Such, G. K. (2018). The endosomal escape of nanoparticles: toward more efficient cellular delivery. Bioconjugate Chemistry, 30(2), 263-272. http://dx.doi.org/10.1021/acs.bioconjchem.8b00732
12. Cupic, K. I., Rennick, J. J., Johnston, A. P., & Such, G. K. (2019). Controlling endosomal escape using nanoparticle composition: current progress and future perspectives. Nanomedicine, 14(2), 215-223. https://doi.org/10.2217/nnm-2018-0326
13. Wang, Y., & Huang, L. (2013). A window onto siRNA delivery. Nature Biotechnology, 31(7), 611-612. https://doi.org/10.1038/nbt.2634
14. Zhu, A., Qu, Q., Shao, X., Kong, B., & Tian, Y. (2012). Carbon-dot-based dual-emission nanohybrid produces a ratiometric fluorescent sensor for in vivo imaging of cellular copper ions. Angewandte Chemie (International ed. in English), 51(29), 7185-7189. https://doi.org/10.1002/anie.201109089
| Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions” | Maha Said, Mustafa Gharib, Samia Zrig, Raphaël Lévy | <p>In hundreds of articles published over the past two decades, nanoparticles have been described as probes for sensing and imaging of a variety of intracellular cytosolic targets. However, nanoparticles generally enter cells by endocytosis with o... | Life Sciences, Medical Sciences, Physical Sciences | Emily Linnane | 2023-11-29 19:14:03 | View | ||
21 Oct 2022
STAGE 1
Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered reportMica B. Carroll*, Grace Edwards*, Chris I. Baker https://osf.io/5e4rg/?view_only=4c8332e3c0b24573ab7960477ed44a62Testing the facilitatory effect of high-frequency transcranial random noise stimulation through enhancement of global motion processingRecommended by Robert McIntosh based on reviews by Sam Westwood and Filippo GhinHigh frequency transcranial random noise stimulation (hf-tRNS) is a relatively novel form of non-invasive brain stimulation, thought to enhance neural excitability and facilitate processing in targeted brain areas. The evidence for the efficacy of hf-tRNS is mixed, so a high-powered test of the proposed facilitatory effects would be of value to the field. This Registered Report will target the human middle temporal complex (hMT+), an area with a well-established critical role in global motion processing. The protocol is adapted from a study by Ghin and colleagues (2018) but focusing on a sub-set of the original experimental conditions and using a fully within-subjects design (n=42). Global motion processing will be operationalised in terms of the coherence threshold for identification of the dominant direction of random-dot motion. The experiment will test the predicted facilitation of contralateral motion processing (reduced coherence threshold) during hf-tRNS to the left hMT+. The specificity of this effect will be tested by comparison to a sham stimulation control condition and an active stimulation control condition (left forehead). By targeting a brain area with a well-established critical role in behaviour, this study will provide important information about the replicability and specificity of the facilitatory effects of hf-tRNS.
Following two rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/bce7u Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Ghin, F., Pavan, A., Contillo, A., & Mather, G. (2018). The effects of high-frequency transcranial random noise stimulation (hf-tRNS) on global motion processing: an equivalent noise approach. Brain Stimulation, 11, 1263–75.
2. Caroll, M. B., Edwards, G. & Baker, C. I. (2022). Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report, in principle acceptance of Version 7 by Peer Community in Registered Reports. https://osf.io/bce7u
| Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report | Mica B. Carroll*, Grace Edwards*, Chris I. Baker | <p>Non-invasive brain stimulation (NIBS) techniques have the potential to demonstrate the causal impact of targeted brain regions on specific behaviors, and to regulate or facilitate behavior in clinical applications. Transcranial random noise sti... | Life Sciences | Robert McIntosh | 2022-06-02 21:25:02 | View | ||
17 Nov 2022
STAGE 1
Removing barriers to plant-based diets: assisting doctors with vegan patientsRomain Espinosa, Thibaut Arpinon, Paco Maginot, Sébastien Demange, and Florimond Peureux https://osf.io/cafyv/?view_only=66eab29c7acb4aebbcec4631cbcb9217Stage 1 acceptance (IPA)Recommended by Zoltan Dienes based on reviews by Joshua Tasoff, Bence Palfi and Alaa AldohThank you for your careful response to the points of myself and the reviewers. I am now happy to award in principle acceptance (IPA). As requested, your submission is being awarded a private Stage 1 acceptance, which will not appear yet on the PCI RR website. Your Stage 1 manuscript has also been registered under the requested 4-year private embargo on the OSF (link below). URL to the preregistered Stage 1 protocol: https://osf.io/fc9gp Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals: | Removing barriers to plant-based diets: assisting doctors with vegan patients | Romain Espinosa, Thibaut Arpinon, Paco Maginot, Sébastien Demange, and Florimond Peureux | <div style="text-align: justify;">Shifting to plant-based diets can alleviate many of the externalities associated with the current food system. Spontaneous shifts in diet are often hindered by consumers’ imperfect knowledge about the health risks... | Medical Sciences, Social sciences | Zoltan Dienes | 2021-08-16 16:50:43 | View | ||
Removing barriers to plant-based diets: assisting doctors with vegan patientsRomain Espinosa, Thibaut Arpinon, Paco Maginot, Sébastien Demange, and Florimond Peureux https://osf.io/kq6eh?view_only=66eab29c7acb4aebbcec4631cbcb9217Informing doctors of the evidence on plant-based dietsRecommended by Zoltan Dienes based on reviews by Alaa Aldoh, Joshua Tasoff and Bence PalfiWhat the best diet is has always been an area of contention. But one thing is clear: Meat is not necessary for health or fitness, and a diet high in plant proteins may well be especially healthy (e.g. Herpich et al., 2022). Further, plant- rather than animal-based diets leave a lower carbon footprint. So what might hold people back from adopting a plant-based diet? One reason is that people may understandably approach their doctor for advice; and the doctor may advise against it, given that many doctors are not well trained in nutrition (Crowley et al., 2019).
Espinosa et al. (2022) conducted a randomised control trial on French general practitioners with 200 doctors given a leaflet and access to an online platform, and 200 controls. The information in the materials concerned the health benefits of plant-based diets, and what nutrients (e.g. B12) may be deficient and what may not be. Attitudes towards and knowledge about plant-based diets was assessed. On a scale of 0-100% expressing whether they would advise for or against (0 = not at all, 100 = absolutely), the intervention shifted attitudes making them more positive about plant based diets by 17 percentage points. However, knowledge of specifically what is worth testing for (e.g. is zinc deficiency more probable or not?) did not change much. The research shows just what can be achieved by a small leaflet (shifting attitudes) and what may require more extensive training (knowledge of relevant medical practice). The Stage 2 manuscript was evaluated over one round of in-depth review. Based on the responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation. URL to the preregistered Stage 1 protocol: https://osf.io/fc9gp Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question existed prior to Stage 1 in-principle acceptance. List of eligible PCI RR-friendly journals: References 1. Crowley, J., Ball, L. & Hiddink, G. J. (2019.) Nutrition in medical education: a systematic review. Lancet Planetary Health. 3, e379–e389. https://doi.org/10.1016/S2542-5196(19)30171-8 2. Herpich, C., Müller-Werdan, U., & Norman, K. (2022). Role of plant-based diets in promoting health and longevity. Maturitas, 165, 47-51. https://doi.org/10.1016/j.maturitas.2022.07.003
3. Espinosa, R., Arpinon, T., Maginot, P., Demange, S. & Peureux, F. (2022). Removing barriers to plant-based diets: assisting doctors with vegan patients, acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/kq6eh?view_only=66eab29c7acb4aebbcec4631cbcb9217
| Removing barriers to plant-based diets: assisting doctors with vegan patients | Romain Espinosa, Thibaut Arpinon, Paco Maginot, Sébastien Demange, and Florimond Peureux | <p>Shifting to plant-based diets can alleviate many of the externalities associated with the current food<br>system. Spontaneous shifts in diet are often hindered by consumers’ imperfect knowledge about the<br>health risks and benefits, which lead... | Medical Sciences, Social sciences | Zoltan Dienes | 2022-08-27 11:01:32 | View | ||
17 Oct 2022
STAGE 1
Relationship between creativity and depression: the role of reappraisal and ruminationChin Yui Lam and Jeffrey Allen Saunders https://osf.io/74vptUnderstanding the relationship between creativity and depressive traitsRecommended by Chris Chambers based on reviews by Kate Button and 1 anonymous reviewerFor centuries, the relationship between creativity and mental health has been a subject of fascination, propelled by the impression that many of the most famous artists in history likely suffered from mood disorders or other mental illnesses. However, with the advent of psychological science – including more precise and diagnostic clinical measures – the empirical evidence for an association between creativity and depressive symptoms has been mixed, with some studies suggesting a positive relationship and others showing either no effect or indicating that the link, if there is one, may be driven by other personality characteristics (Verhaeghen et al., 2005).
In the current study, Lam and Saunders will use an online design in 200 participants to ask whether creativity is associated with higher depressive traits, and further, whether that relationship depends on two additional variables that could explain an observed positive correlation: self-reflective rumination (repetitive thoughts that maintain a negative mood state) and the frequency with which individuals engage in reappraisal (a regulation strategy that involves reinterpreting an event or situation to diminish its negative impact). If justified by the main confirmatory findings, the authors will also explore the moderating role of gender and how any observed associations are reflected in more fine-grained measures of creativity. The results promise to shed light on not only the basic question of whether creativity is related to depressive traits, but the extent to which that association depends on related determinants of mental health.
Following two rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/yub7n
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Verhaeghen, P., Joormann, J., & Khan, R. (2005). Why we sing the blues: The relation between self-reflective rumination, mood, and creativity. Emotion, 5(2), 226-232. https://doi.org/10.1037/1528-3542.5.2.226
2. Lam, C. Y. & Saunders, J. A. (2022). Relationship between creativity and depression: the role of reappraisal and rumination, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/yub7n
| Relationship between creativity and depression: the role of reappraisal and rumination | Chin Yui Lam and Jeffrey Allen Saunders | <p>Previous research has found mixed evidence about whether increased creativity is associated with higher depression. We investigated the relationship between creativity and depression, and the role of two emotion regulation strategies: ruminatio... | Social sciences | Chris Chambers | 2022-01-27 10:53:10 | View | ||
Relationship between creativity and depression: the role of reappraisal and ruminationChin Yui Lam and Jeffrey Allen Saunders https://osf.io/z3ap5Evidence for a weak relationship between creativity and depressive traitsRecommended by Chris ChambersFor centuries, the relationship between creativity and mental health has been a subject of fascination, propelled by the impression that many of the most famous artists in history likely suffered from mood disorders or other mental illnesses. However, with the advent of psychological science – including more precise and diagnostic clinical measures – the empirical evidence for an association between creativity and depressive symptoms has been mixed, with some studies suggesting a positive relationship and others showing either no effect or indicating that the link, if there is one, may be driven by other personality characteristics (Verhaeghen et al., 2005).
In the current study, Lam and Saunders used an online design in 201 participants to ask whether creativity is associated with higher depressive traits, and further, whether that relationship depends on two additional variables that could explain an observed positive correlation: self-reflective rumination (repetitive thoughts that maintain a negative mood state) and the frequency with which individuals engage in reappraisal (a regulation strategy that involves reinterpreting an event or situation to diminish its negative impact).
Results showed mixed support for the hypotheses. Contrary to expectations, the relationship between creativity and depression was significantly negative rather than positive. However, even though the directionality of this relationship was opposite to predicted, the hypothesis that the association between creativity and depression is mediated by self-reflective rumination was supported. Finally, the results disconfirmed the hypothesis that reappraisal frequency contributes to the relationship between creativity and depression. Exploratory analyses indicated no reliable moderating role of gender. Overall, these findings suggest that creativity and depression may be only weakly related, and that self-reflective rumination could account for that relationship.
The Stage 2 manuscript was evaluated over one round of review provided by the recommender and Managing Board, as the Stage 1 reviewers were no longer available. Based on additional changes to the manuscript, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
URL to the preregistered Stage 1 protocol: https://osf.io/yub7n
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. List of eligible PCI RR-friendly journals:
References
1. Verhaeghen, P., Joormann, J., & Khan, R. (2005). Why we sing the blues: The relation between self-reflective rumination, mood, and creativity. Emotion, 5, 226-232. https://doi.org/10.1037/1528-3542.5.2.226
2. Lam, C. Y. & Saunders, J. A. (2023). Relationship between creativity and depression: the role of reappraisal and rumination [Stage 2 Registered Report]. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/z3ap5
| Relationship between creativity and depression: the role of reappraisal and rumination | Chin Yui Lam and Jeffrey Allen Saunders | <p>Previous research has found mixed evidence about whether increased creativity is associated with higher depression. We investigated the relationship between creativity and depression, and the role of two emotion regulation strategies: ruminatio... | Social sciences | Chris Chambers | 2023-07-27 11:42:43 | View | ||
27 Mar 2024
STAGE 1
Registered Report: Are anticipatory predictions enhanced in tinnitus and independent of hearing loss?L. Reisinger, G. Demarchi, S. Rösch, E. Trinka, J. Obleser, N. Weisz https://osf.io/t34p8Can predictive coding explain subjective tinnitus?Recommended by Chris Chambers based on reviews by Will Sedley, Pia Brinkmann and Emilie CardonSubjective tinnitus is a common disorder in which people experience a persistent sound in the absence of any external source. The underlying causes of tinnitus are debated – although the condition is strongly associated with hearing loss resulting from auditory damage, much remains to be understood about the neural processes that give rise to the phantom perception. Various classes of neurophysiological theories have been proposed, including the “altered gain” model – in which neurons in the auditory pathway increase their responsiveness to compensate for reduced auditory input following hearing loss – and the “noise cancellation” model – in which disrupted feedback connections from limbic regions are unable to tune out phantom signals. Although these theories account for much observed data, they have not been conclusively supported, and their ability to explain tinnitus is limited by the fact that hearing loss and tinnitus can arise independently and at different times.
In the current study, Reisinger et al. (2023) will test an emerging alternative theory based on a Bayesian predictive-coding framework (Sedley et al., 2016) in which the alteration of perceptual priors leads the auditory system to expect a sound that, if functioning normally, it should not expect. Using magnetoencephalography (MEG) in a sample of tinnitus patients (and carefully-matched controls for age, gender, and level of hearing loss), they will ask whether tinnitus is associated with anticipatory brain activation, tuned to the carrier-frequency of an expected auditory stimulus. Specifically, the authors predict that if the predictive-coding framework is correct then individuals with tinnitus should show different regularity-dependent pre-activations of carrier- frequency-specific information compared to the control group, while tone carrier-frequencies should be processed normally in tinnitus patients. They also predict that any such pre-activations should not be related to levels of reported subjective tinnitus distress, as measured with the short version of the Tinnitus Questionnaire (mini-TQ).
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
URL to the preregistered Stage 1 protocol: https://osf.io/6gvpy
Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence.
List of eligible PCI RR-friendly journals:
References
Reisinger, L., Demarchi, G., Rösch, , S., Trinka, E., Obleser, L., & Weisz, N. (2023). Registered Report: Are anticipatory predictions enhanced in tinnitus and independent of hearing loss? In principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/6gvpy
Sedley, W., Friston, K. J., Gander, P. E., Kumar, S., & Griffiths, T. D. (2016). An integrative tinnitus model based on sensory precision. Trends in Neurosciences, 39, 799-812. https://doi.org/10.1016/j.tins.2016.10.004
| Registered Report: Are anticipatory predictions enhanced in tinnitus and independent of hearing loss? | L. Reisinger, G. Demarchi, S. Rösch, E. Trinka, J. Obleser, N. Weisz | <p>Phantom perceptions occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind phantom perceptions like tinnitus are not well understood. The dominant view suggests that tinnitus results from hyperactiv... | Life Sciences | Chris Chambers | 2023-01-03 08:35:12 | View | ||
Registered Report: Are anticipatory auditory predictions enhanced in tinnitus and independent of hearing loss?L. Reisinger, G. Demarchi, S. Rösch, E. Trinka, J. Obleser, N. Weisz https://osf.io/9wqjhEvidence for the role of predictive coding in subjective tinnitusRecommended by Chris Chambers based on reviews by Will Sedley, Pia Brinkmann and Emilie CardonSubjective tinnitus is a common disorder in which people experience a persistent sound in the absence of any external source. The underlying causes of tinnitus are debated – although the condition is strongly associated with hearing loss resulting from auditory damage, much remains to be understood about the neural processes that give rise to the phantom perception. Various classes of neurophysiological theories have been proposed, including the “altered gain” model – in which neurons in the auditory pathway increase their responsiveness to compensate for reduced auditory input following hearing loss – and the “noise cancellation” model – in which disrupted feedback connections from limbic regions are unable to tune out phantom signals. Although these theories account for much observed data, they have not been conclusively supported, and their ability to explain tinnitus is limited by the fact that hearing loss and tinnitus can arise independently and at different times.
In the current study, Reisinger et al. (2024) tested an emerging alternative theory based on a Bayesian predictive-coding framework (Sedley et al., 2016) in which the alteration of perceptual priors leads the auditory system to expect a sound that, if functioning normally, it should not expect. Using magnetoencephalography (MEG) in a sample of tinnitus patients (and carefully-matched controls for age, gender, and level of hearing loss), they asked whether tinnitus is associated with anticipatory brain activation, tuned to the carrier-frequency of an expected auditory stimulus. Specifically, the authors predicted that if the predictive-coding framework is correct then individuals with tinnitus should show different regularity-dependent pre-activations of carrier- frequency-specific information compared to the control group, while tone carrier-frequencies should be processed normally in tinnitus patients. They also predicted that any such pre-activations should not be related to levels of reported subjective tinnitus distress, as measured with the short version of the Tinnitus Questionnaire (mini-TQ).
The results broadly confirmed the hypotheses, with some caveats. Statistically significant differences in regularity-dependent pre-activations were observed between the tinnitus and control groups, however – curiously – the effects appear to be driven by below-chance decoding in the control group, complicating the interpretration. At the same time, consistent with expectations, frequency processing did not differ significantly between individuals with and without tinnitus, and the observed pre-activations were not significantly related to tinnitus distress. Overall, the findings cautiously support the conclusion that chronic tinnitus is associated with maladaptively upregulated predictive neural processing, and that this phenomenon is unlikely to be explained by either tinnitus distress or hearing loss.
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
URL to the preregistered Stage 1 protocol: https://osf.io/6gvpy
Level of bias control achieved: Level 3. At least some data/evidence that was used to the answer the research question had been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they had yet observed any part of the data/evidence prior to Stage 1 IPA.
List of eligible PCI RR-friendly journals:
References
1. Reisinger, L., Demarchi, G., Rösch, , S., Trinka, E., Obleser, L., & Weisz, N. (2024). Registered Report: Are anticipatory auditory predictions enhanced in tinnitus and independent of hearing loss? [Stage 2] Acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/9wqjh
2. Sedley, W., Friston, K. J., Gander, P. E., Kumar, S., & Griffiths, T. D. (2016). An integrative tinnitus model based on sensory precision. Trends in Neurosciences, 39, 799-812. https://doi.org/10.1016/j.tins.2016.10.004
| Registered Report: Are anticipatory auditory predictions enhanced in tinnitus and independent of hearing loss? | L. Reisinger, G. Demarchi, S. Rösch, E. Trinka, J. Obleser, N. Weisz | <p>Phantom perceptions occur without any identifiable environmental or bodily source. The mechanisms and key drivers behind phantom perceptions like tinnitus are not well understood. The dominant “altered-gain”-framework suggests that tinnitus res... | Life Sciences | Chris Chambers | 2024-02-21 16:17:33 | View |
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