Rapid learning in response to pain is a crucial survival mechanism, relying on forming associations between cues in the environment and subsequent pain or injury. Existing evidence suggests that associations between conditioned stimuli (cues) and unconditioned aversive stimuli (such as pain) are learned faster than for appetitive stimuli that signal pain relief. In addition, when the link between a conditioned and unconditioned stimulus is broken (by unpairing them), the extinction of this learning effect is slower for aversive that appetitive stimuli, resulting in a flatter extinction slope. Understanding why extinction slopes are reduced for aversive stimuli is important for advancing theoretical models of learning, and for devising ways of increasing the slope (and thus facilitating extinction learning) could help develop more effective methods of pain relief, particularly in the treatment of chronic pain.

 

In the current programmatic submission, Busch et al. (2023) will undertake two Registered Reports to test whether a verbal instruction intervention that explicitly informs participants about contingency changes between conditioned and unconditioned stimuli facilitates extinction learning, especially for aversive (painful) stimuli, and how changes in extinction learning relate to neural biomarkers of functional connectivity. In the first Registered Report, they will initially seek to replicate previous findings including faster acquisition of aversive than appetitive conditioned stimuli as well as incomplete extinction of aversive conditioned stimuli without verbal instruction. They will then test how the instruction intervention alters extinction slopes and the completeness of extinction for appetitive and aversive stimuli, using a range of behavioral measures (expectancy and valence ratings) and physiological measures (pupillometry, skin conductance responses). To shed light on the neural correlates of these processes, in the second Registered Report the authors will use functional magnetic resonance imaging (fMRI) to ask firstly how acquisition and extinction of aversive and appetitive conditioned responses are related to resting state brain connectivity within a network that includes ventromedial prefrontal cortex, amygdala, and striatum, and secondly, whether the effectiveness of instruction on extinction learning is associated with differences in resting state connectivity across this network.

 

The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

 

URL to the preregistered Stage 1 protocol: https://osf.io/cj75p (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 

 

1. Busch, L., Wiech, K., Gamer, M., Knicses, B., Spisak, T., Schmidt, K., & Bingel, U. (2023). Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered report. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/cj75p

Subjective tinnitus is a common disorder in which people experience a persistent sound in the absence of any external source. The underlying causes of tinnitus are debated – although the condition is strongly associated with hearing loss resulting from auditory damage, much remains to be understood about the neural processes that give rise to the phantom perception. Various classes of neurophysiological theories have been proposed, including the “altered gain” model – in which neurons in the auditory pathway increase their responsiveness to compensate for reduced auditory input following hearing loss – and the “noise cancellation” model –  in which disrupted feedback connections from limbic regions are unable to tune out phantom signals. Although these theories account for much observed data, they have not been conclusively supported, and their ability to explain tinnitus is limited by the fact that hearing loss and tinnitus can arise independently and at different times.

 

In the current study, Reisinger et al. (2023) will test an emerging alternative theory based on a Bayesian predictive-coding framework (Sedley et al., 2016) in which the alteration of perceptual priors leads the auditory system to expect a sound that, if functioning normally, it should not expect. Using magnetoencephalography (MEG) in a sample of tinnitus patients (and carefully-matched controls for age, gender, and level of hearing loss), they will ask whether tinnitus is associated with anticipatory brain activation, tuned to the carrier-frequency of an expected auditory stimulus. Specifically, the authors predict that if the predictive-coding framework is correct then individuals with tinnitus should show different regularity-dependent pre-activations of carrier- frequency-specific information compared to the control group, while tone carrier-frequencies should be processed normally in tinnitus patients. They also predict that any such pre-activations should not be related to levels of reported subjective tinnitus distress, as measured with the short version of the Tinnitus Questionnaire (mini-TQ).

 

The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

 

 

Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence.

 

 

• Brain and Neuroscience Advances
• Cortex
• F1000Research
• In&Vertebrates
• NeuroImage: Reports
• Peer Community Journal
• PeerJ
• Psychology of Consciousness: Theory, Research and Practice
• Royal Society Open Science

 

 

Reisinger, L., Demarchi, G., Rösch, , S., Trinka, E., Obleser, L., & Weisz, N.  (2023). Registered Report: Are anticipatory predictions enhanced in tinnitus and independent of hearing loss? In principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/6gvpy

 

Sedley, W., Friston, K. J., Gander, P. E., Kumar, S., & Griffiths, T. D. (2016). An integrative tinnitus model based on sensory precision. Trends in Neurosciences, 39, 799-812. https://doi.org/10.1016/j.tins.2016.10.004

Stress is a familiar presence in modern life and may be rising in severity (Almeida et al., 2020). As a key driver of many health problems, controlling stress and its impacts is a central goal in clinical and health psychology, yet the effectiveness of existing interventions to regulate stress remains unclear. 

 

In the current study, Sparacio et al tackled this question from a meta-analytic perspective, focusing on a corpus of existing research that has addressed the efficacy of two specific stress regulation interventions: being in nature and emotional social support. As well as evaluating the evidential content of the relevant literatures, the authors also examined signs of publication bias and the moderating role of personality traits.

 

After correcting for publication bias, the results reveal evidence that being in nature is effective at reducing stress while emotional social support is not. The moderating role of personality for both interventions was inconclusive due to lack of evidence. In addition, the quality of the surveyed literature was found to be low overall, suffering from a high risk of bias and high rate of statistical reporting errors. The authors offer several recommendations to improve the rigour and quality of studies in this field, including open data, open materials, code review, preregistration and the use of Registered Reports.

 

The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.

 

URL to the preregistered Stage 1 protocol: https://osf.io/c25qw

 

Level of bias control achieved: Level 3. At least some data/evidence that was used to the answer the research question had been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they did not observe ANY part of the data/evidence prior to Stage 1 IPA.

 

 

• F1000Research
• Peer Community Journal
• PeerJ
• Royal Society Open Science
• Swiss Psychology Open

 

 

1. Almeida, D. M., Charles, S. T., Mogle, J., Drewelies, J., Aldwin, C. M., Spiro, A. III, & Gerstorf, D. (2020). Charting adult development through (historically changing) daily stress processes. American Psychologist, 75(4), 511–524. https://doi.org/10.1037/amp0000597

 

2. Sparacio, A., Ropovik, I., Jiga-Boy, G. M., Lağap, A. C. & IJzerman, H. (2023). Stage 2 Registered Report: Stress regulation via being in nature and social support in adults, a meta-analysis. Acceptance of version 2 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/a4zmj

The relationship between music and exercise has been studied for over a century, with implications for our understanding of biomechanics, physiology, brain function, and psychology. Listening to music while exercising is associated with a wide range of benefits, from increasing motivation, to reducing perceived exertion, inhibiting awareness of negative bodily signals, boosting mood, and ultimately improving physical performance. But while these ergogenic benefits of music are well documented, much remains to be discovered about how music alters brain function during exercise. One reason for this gap in understanding is the technical difficulty in recording brain activity during realistic exercise, as neuroimaging methods such as fMRI, EEG or MEG typically require participants to remain as still as possible.

 

In the current study, Guérin et al. (2023) will use the optical brain imaging technique of functional near infrared spectroscopy (fNIRS) to measure oxygenation of key brain areas during exercise. Unlike other neuroimaging methods, fNIRS has a high tolerance for motion artefacts, making it the ideal method of choice for the current investigation. The authors propose a series of hypotheses based on previous studies that observed a decrease in cerebral oxygenation during intense exercise, particularly within the medial prefrontal cortex (mPFC) and dorsolateral prefrontal cortex (dlPFC). If, as suggested, the prefrontal cortex is important for regulation of cognition and emotion during exercise, then the benefits of listening to music might arise by delaying or reducing this drop in prefrontal oxygenation.

 

Using a within-subject designs, Guérin et al. will combine an incremental exercise protocol involving a cycling task with three auditory conditions: asynchronous music (the active condition), listening to an audiobook (an auditory control) or silence (baseline control). Compared to the two control conditions, they predict that music exposure will increase oxygenation in prefrontal and parietal regions and will also delay the drop in oxygenation associated with intense exercise (specifically within dlPFC and mPFC). To test whether any such changes are specific for prefrontal and parietal cortex, they will also compare the haemodynamic responses of the occipital cortex between the auditory conditions, predicting no difference.

 

The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

 

URL to the preregistered Stage 1 protocol: https://osf.io/52aeb
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 

The world is seemingly awash with conspiracy theories – from well-trodden examples such as fake Moon landings, the 9/11 truth movement, and Holocaust denial, to relative newcomers including COVID as a bioweapon, QAnon, and the belief that the science of climate change has been invented or falsified. While there is a public perception that conspiracy theories are becoming more prevalent, recent evidence suggests that the rate of conspiracism is relatively stable over time (Uscinski et al., 2022). At any point in history, it seems that a certain proportion of people find themselves vulnerable to conspiracy beliefs, but what distinguishes those who do from those who don’t, and what are the causal factors?

 

In the current study, Liekefett et al. (2023) investigate the critical role of rumination – a perseverative and repetitive focus on negative content leading to emotional distress. In particular, the authors ask whether one component of rumination referred to as brooding (dwelling on one’s worries and distressing emotions) has a specific causal role in the formation of conspiracy beliefs. In a series of preliminary experiments, the authors first established a procedure for successfully inducing rumination, identifying various boundary conditions and requirements for a successful design. In the proposed study (of up to N=1,638), they will then ask whether the induction of brooding causes a significant increase in conspiracy beliefs. Manipulation checks will be included to confirm intervention fidelity (independently of this hypothesis), and exploratory analyses will test the effect of various moderators, as well as the causal role of a complementary manipulation of reflection – a component of rumination in which attention is focused on the issue at hand rather than one’s emotions.

 

The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

 

URL to the preregistered Stage 1 protocol: https://osf.io/y82bs
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 

• Advances in Cognitive Psychology
• Experimental Psychology
• Journal of Cognition
• Peer Community Journal
• PeerJ
• Royal Society Open Science
• Swiss Psychology Open

 

References
 

1. Uscinski, J., Enders, A., Klofstad, C., Seelig, M., Drochon, H., Premaratne, K. & Murthi, M. (2022) Have beliefs in conspiracy theories increased over time? PLOS ONE 17: e0270429. https://doi.org/10.1371/journal.pone.0270429

2. Liekefett, L. Sebben, S. & Becker, J. C. (2023). Does Brooding Meaningfully Increase the Likelihood of Believing in a Conspiracy? Stage 1 Registered Report, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/y82bs