PCI Registered Reports

YAMADA Yuki

Nusu Lab, Kyushu University, Fukuoka, Japan
Social sciences
recommender, manager

Recommendations: 6

Reviews: 2

Website https://sites.google.com/site/yamadayuk/

Areas of expertise

I am interested in psychological, physiological and biological mechanisms pertaining to the following: - Laterality - Disgust and Happiness - Psychological space, time and number - Attention and awareness for constructing dynamic mental representations - Effects of emotion, affection, mood, personality, and culture on mental information processing - Embodied emotion and social emotion https://sites.google.com/site/yamadayuk/

Recommendations: 6

22 Jul 2024

STAGE 1

Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”

Maha Said, Mustafa Gharib, Samia Zrig, Raphaël Lévy https://osf.io/kf9qe/

Replicating, Revising and Reforming: Unpicking the Apparent Nanoparticle Endosomal Escape Paradox

Recommended by Emily Linnane and Yuki Yamada based on reviews by Cecilia Menard-Moyon and Zeljka Krpetic

Context

Over the past decade there has been an exponential increase in the number of research papers utlising nanoparticles for biological applications such as intracellular sensing [1, 2], theranostics [3-5] and more recently drug delivery and precision medicine [6, 7]. Despite the success stories, there is a disconnect regarding current dogma on issues such as nanoparticle uptake and trafficking, nanoparticle delivery via the enhanced permeability and retention (EPR) effect, and endosomal escape. Critical re-evaluation of these concepts both conceptually and experimentally is needed for continued advancement in the field.

For this preregistration, Said et al. (2024) focus on nanoparticle intracellular trafficking, specifically endosomal escape [8]. The current consensus in the literature is that nanoparticles enter cells via endocytosis [9, 10] but reportedly just 1-2% of nanoparticles/ nanoparticle probes escape endosomes and enter the cytoplasm [11-13]. There is therefore an apparent paradox over how sensing nanoparticles can detect their intended targets in the cytoplasm if they are trapped within the cell endosomes. To address this fundamental issue of nanoparticle endosomal escape, Lévy and coworkers are carrying out replication studies to thoroughly and transparently replicate the most influential papers in the field of nanoparticle sensing. The aim of these replication studies is twofold: to establish a robust methodology to study endosomal escape of nanoparticles, and to encourage discussions, transparency and a step-change in the field.

Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”

For this replication study, the authors classified papers on the topic of nanoparticle sensing and subsequently ranked them by number of citations. Based on this evaluation they selected a paper by Zhu and colleagues [14] entitled “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions” for their seminal replication study. To determine the reproducibility of the results from Zhu et al., the authors aim to establish the proportion of endosomal escape of the nanoparticles, and to examine the data in a biological context relevant to the application of the probe.

Beyond Replication

The authors plan to replicate the exact conditions reported in the materials and methods section of the selected paper such as nanoparticle probe synthesis of CdSe@C-TPEA nanoparticles, assessment of particle size, stability and reactivity and effect on cells (TEM, pH experiments, fluorescent responsivity to metal ions and cell viability). In addition, Said et al., plan to include further experimental characterisation to complement the existing study by Zhu and colleagues. They will incorporate additional controls and methodology to determine the intracellular location of nanoparticle probes in cells including: quantifying excess fluorescence in the culture medium, live cell imaging analysis, immunofluorescence with endosomal and lysosomal markers, and electron microscopy of cell sections. The authors will also include supplementary viability studies to assess the impact of the nanoparticles on HeLa cells as well as an additional biologically relevant cell line (for use in conjunction with the HeLa cells as per the original paper).

The Stage 1 manuscript underwent two rounds of thorough in-depth review. After considering the detailed responses to the reviewers' comments, the recommenders determined that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).

The authors have thoughtfully considered their experimental approach to the replication study, whilst acknowledging any potential limitations. Given that conducting such a replication study is novel in the field of Nanotechnology and there is currently no ‘gold standard’ approach in doing so, the authors have showed thoughtful regard of statistical analysis and unbiased methodology where possible.

Based on current information, this study is the first use of preregistration via Peer Community in Registered Reports and the first formalised replication study in Nanotechnology for Biosciences. The outcomes of this of this study will be significant both scientifically and in the wider context in discussion of the scientific method.

URL to the preregistered Stage 1 protocol: https://osf.io/qbxpf

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly Journals:

References

1. Howes, P. D., Chandrawati, R., & Stevens, M. M. (2014). Colloidal nanoparticles as advanced biological sensors. Science, 346(6205), 1247390. https://doi.org/10.1126/science.1247390

2. Liu, C. G., Han, Y. H., Kankala, R. K., Wang, S. B., & Chen, A. Z. (2020). Subcellular performance of nanoparticles in cancer therapy. International Journal of Nanomedicine, 675-704. https://doi.org/10.2147/IJN.S226186

3. Tang, W., Fan, W., Lau, J., Deng, L., Shen, Z., & Chen, X. (2019). Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics. Chemical Society Reviews, 48(11), 2967-3014. https://doi.org/10.1039/C8CS00805A

4. Yoon, Y. I., Pang, X., Jung, S., Zhang, G., Kong, M., Liu, G., & Chen, X. (2018). Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics. Journal of Materials Chemistry B, 6(20), 3235-3239. https://doi.org/10.1039%2FC8TB00368H

5. Lin, H., Chen, Y., & Shi, J. (2018). Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy. Chemical Society Reviews, 47(6), 1938-1958. https://doi.org/10.1039/C7CS00471K

6. Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021). Lipid nanoparticles for mRNA delivery. Nature Reviews Materials, 6(12), 1078-1094. https://doi.org/10.1038/s41578-021-00358-0

7. Mitchell, M. J., Billingsley, M. M., Haley, R. M., Wechsler, M. E., Peppas, N. A., & Langer, R. (2021). Engineering precision nanoparticles for drug delivery. Nature Reviews Drug Discovery, 20(2), 101-124. https://doi.org/10.1038/s41573-020-0090-8

8. Said, M., Gharib, M., Zrig, S., & Lévy, R. (2024). Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/qbxpf

9. Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., ... & Mahmoudi, M. (2017). Cellular uptake of nanoparticles: Journey inside the cell. Chemical Society Reviews, 46(14), 4218-4244. https://doi.org/10.1039/C6CS00636A

10. de Almeida, M. S., Susnik, E., Drasler, B., Taladriz-Blanco, P., Petri-Fink, A., & Rothen-Rutishauser, B. (2021). Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine. Chemical society reviews, 50(9), 5397-5434. https://doi.org/10.1039/D0CS01127D

11. Smith, S. A., Selby, L. I., Johnston, A. P., & Such, G. K. (2018). The endosomal escape of nanoparticles: toward more efficient cellular delivery. Bioconjugate Chemistry, 30(2), 263-272. http://dx.doi.org/10.1021/acs.bioconjchem.8b00732

12. Cupic, K. I., Rennick, J. J., Johnston, A. P., & Such, G. K. (2019). Controlling endosomal escape using nanoparticle composition: current progress and future perspectives. Nanomedicine, 14(2), 215-223. https://doi.org/10.2217/nnm-2018-0326

13. Wang, Y., & Huang, L. (2013). A window onto siRNA delivery. Nature Biotechnology, 31(7), 611-612. https://doi.org/10.1038/nbt.2634

14. Zhu, A., Qu, Q., Shao, X., Kong, B., & Tian, Y. (2012). Carbon-dot-based dual-emission nanohybrid produces a ratiometric fluorescent sensor for in vivo imaging of cellular copper ions. Angewandte Chemie (International ed. in English), 51(29), 7185-7189. https://doi.org/10.1002/anie.201109089

30 May 2024

STAGE 1

Does learning more about others impact liking them?: Replication and extension Registered Report of Norton et al. (2007)’s Lure of Ambiguity

Zöe Horsham, Ashleigh Haydock-Symonds, Hirotaka Imada, Hiu Ching Tai, Wing Lam Lau, Tsz Lui Shum, Yuqing Zeng, Hiu Tang Chow, Gilad Feldman https://osf.io/eygzp

Does familiarity really breed contempt?

Recommended by Yuki Yamada based on reviews by Philipp Schoenegger and Zoltan Kekecs

In interpersonal evaluation, the amount of information available about the other person has a significant impact. Norton et al. (2007) conducted systematic experiments suggesting a 'less is more' effect – that a lack of information leads to a more positive evaluation. However, subsequent studies have not always reached the same conclusion.

In the current study, Horsham et al. (2024) aim to address this issue by conducting direct and conceptual replications of the Norton et al. (2007) experiments, as well as additional extensive experiments focusing on the effects of curiosity. The authors seek to confirm in a reliable way the relationship between ambiguity and liking, and even to clarify the factors that mediate this relationship. The results should significantly advance our understanding of the importance of information management in interpersonal relationships.

The Stage 1 manuscript was peer-reviewed by two experts; after four rounds of review and based on their revisions and detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and awarded it in-principle acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/7mc4y

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly journals:

References

1. Norton, M. I., Frost, J. H., & Ariely, D. (2007). Less is more: The lure of ambiguity, or why familiarity breeds contempt. Journal of Personality and Social Psychology, 92, 97-105. https://doi.org/10.1037/0022-3514.92.1.97

2. Horsham, Z., Haydock-Symonds, A., Imada, H., Tai, H. C., Lau, W. L., Shum, T. L., Zeng, Y., Chow, H. T., & Feldman, G., (2024). Does learning more about others impact liking them? Replication and extension Registered Report of Norton et al. (2007)’s Lure of Ambiguity. In principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/7mc4y

28 Mar 2024

STAGE 1

Working memory performance in adverse environments: Enhanced, impaired, or intact?

Stefan Vermeent, Anna-Lena Schubert, Meriah L. DeJoseph, Jaap J. A. Denissen, Jean-Louis van Gelder, Willem E. Frankenhuis https://github.com/StefanVermeent/liss_wm_profiles_2023/blob/master/manuscript/manuscript.pdf

A closer look at working memory changing with adversity

Recommended by Yuki Yamada based on reviews by Kathryn Bates and 1 anonymous reviewer

Adverse environments involving threat, uncertainty, deprivation and stress can cause significant and long-lasting harm to cognition and development. In this Stage 1 protocol, Vermeent and colleagues (2024) aim to simultaneously test with a single paradigm and statistical model for findings from previous studies showing that human working memory capacity is impaired in adverse environments, as well as other evidence suggesting that adversity may actually enhance updating of working memory. Furthermore, they will also investigate whether working memory is related to each of the adversity types: threat, deprivation, and unpredictability.

The findings of this study should help clarify how working memory functions in combination with adversity, and will provide insight into the development of better interventions and training methods for optimal performance in a variety of environments.

The manuscript was reviewed by two experts and the recommender. Following two rounds of peer review, and based on detailed responses to the reviewers' comments, I, the recommender, judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/dp7wc

Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence.

List of eligible PCI RR-friendly journals:

References

1. Vermeent, S., Schubert, A.-L., DeJoseph, M. L., Denissen, J. J. A, van Gelder, J.-L. & Frankenhuis, W. E. (2024). Working memory performance in adverse environments: Enhanced, impaired, or intact? In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/dp7wc

07 Apr 2023

STAGE 1

The WEIRD problem in a “non-WEIRD” context: A meta-research on the representativeness of human subjects in Chinese psychological research

YUE Lei, ZUO Xi-Nian, HU Chuan-Peng https://osf.io/dkmt3/

How well do "non-WEIRD" participants in multi-lab studies represent their local population?

Recommended by Yuki Yamada based on reviews by Zoltan Dienes, Patrick Forscher and Kai Hiraishi

In this protocol, Yue et al. (2023) aim to clarify whether the sample of non-WEIRD countries included in multi-lab studies is actually representative of those countries and cultures. Focusing on China, this study will compare Chinese samples in several multi-lab studies with participants in studies published in leading national Chinese journals on various aspects, including demographic data and geographic information. This work will provide useful information on the extent to which multi-lab studies are able to deal with generalizability, especially as they intend to address the generalizability problem.

The Stage 1 manuscript was reviewed by three experts, including two with an interest in the WEIRD problem and a wealth of experience in open science and multi-lab research, plus an expert in Bayesian statistics, which this manuscript uses. Following multilpe rounds of peer review, and based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/ehw54

Level of bias control achieved: Level 4. At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors (e.g. residing in a public database or with a colleague) BUT the authors certify that they have not yet accessed any part of that data/evidence.

List of eligible PCI RR-friendly journals:

References

Yue, L., Zuo, X.-N., & Hu, C.-P. (2023) The WEIRD problem in a “non-WEIRD” context: A meta-research on the representativeness of human subjects in Chinese psychological research, in principle acceptance of Version 7 by Peer Community in Registered Reports. https://osf.io/ehw54

13 Feb 2023

STAGE 2
(Go to stage 1)

Sight vs. sound judgments of music performance depend on relative performer quality: Cross-cultural evidence from classical piano and Tsugaru shamisen competitions [Stage 2 Registered Report]

Gakuto Chiba, Yuto Ozaki, Shinya Fujii, Patrick E. Savage https://doi.org/10.31234/osf.io/xky4j

Music is appreciated cross-modally, but is culture- and context-dependent

Recommended by Yuki Yamada based on reviews by Kyoshiro Sasaki and 1 anonymous reviewer

Music is not merely limited to the aural experience we garner through our auditory faculties, as commonly perceived. Rather, various studies have explored the cross-modal impact of visual stimuli on the evaluation of music. These previous studies have been confined exclusively to Western music. Hence, Chiba et al. (2023) designed a study with a focus on the Tsugaru shamisen, a renowned folk instrument indigenous to Japan, and of which the first author is an outstanding player.

The study methodology was an improved version of previous endeavors, wherein actual musical material sourced from concours performances was displayed through audio-only, video-only or both modalities. A sample of Japanese participants were then asked to evaluate the concours performances on both the piano and the Tsugaru shamisen. The results, obtained through pre-registered protocols, revealed that for both concours performances, the participants displayed a cross-modal impact of visual information on their aural evaluation of music. This effect was also found to be contingent on cultural and contextual factors. These outcomes furnish valuable evidence towards the generalizability of the interplay between sight and sound in the assessment of music.

The study underwent rigorous peer-review processes in both Stage 1 and Stage 2, with three experts specializing in Japanese folk music, open science, and statistics, respectively, providing their critical assessments. Following multiple rounds of revision, the final manuscript was deemed fit for recommendation.

URL to the preregistered Stage 1 protocol: https://osf.io/ry2b6

Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.

List of eligible PCI RR-friendly journals:

References

Chiba G., Ozaki Y., Fujii S., & Savage P.E. (2023). Sight vs. sound judgments of music performance depend on relative performer quality: Cross-cultural evidence from classical piano and Tsugaru shamisen competitions [Stage 2 Registered Report]. Acceptance of Version 2 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/xky4j

28 Dec 2021

STAGE 1

Sight vs. sound in the judgment of music performance: Cross-cultural evidence from classical piano and Tsugaru shamisen competitions

Gakuto Chiba, Yuto Ozaki, Shinya Fujii, Patrick E. Savage https://doi.org/10.31234/osf.io/xky4j

Understanding the role of visual and auditory information in evaluating musical performance

Recommended by Yuki Yamada based on reviews by David Hughes and Kyoshiro Sasaki

In this Stage 1 Registered Report, Chiba and colleagues (2021) aim to investigate how people use information from visual and auditory modalities when evaluating musical performances. Previous studies, mainly using Western music, have reported a visual dominance, but this has not yet been clearly and consistently reported. Thus, the authors propose to evaluate both the reproducibility and generalizability of the previous findings by conducting a replication study using the methodology of the previous studies and by introducing a new experimental condition in which the Tsugaru-shamisen, a unique Japanese musical instrument, is also performed. This study could represent an important turning point in the research context of performance evaluation and would be of considerable value.

This manuscript was peer-reviewed by two experts in scientific methodology and Japanese traditional music, respectively, and during the two-round peer-review process they made a number of important points, but eventually awarded the manuscript a highly positive response. I am therefore pleased to recommend that this Stage 1 Registered Report meets our Stage 1 criteria and is worthy of in-principle acceptance. I look forward to seeing the results and discussion reported in Stage 2, with the expectation that the experiment conducted by the authors will be in strict accordance with this protocol.

*The following is a very minor comment, which I hope the authors will find helpful in the future. Of course, this is not related to hypothesis construction and does not require revision: The "Blind Audition" study cited in the introduction is very impactful, but has recently been called into question, so I am at least a little cautious when citing this study. This article may be useful. https://www.wsj.com/articles/blind-spots-in-the-blind-audition-study-11571599303

URL to the preregistered Stage 1 protocol: https://osf.io/ry2b6

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly journals:

References

Chiba G, Ozaki Y, Fujii S, Savage PE (2021) Sight vs. sound in the judgment of music performance: Cross-cultural evidence from classical piano and Tsugaru shamisen competitions [Stage 1 Registered Report]. Psyarxiv, xky4j, stage 1 preregistration, in-principle acceptance of version 5 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/xky4jhttps://doi.org/10.17605/OSF.IO/RY2B6

Reviews: 2

11 Apr 2023

STAGE 2
(Go to stage 1)

Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

Molly Carlyle1*, Malin Kvande*, Isabell M. Meier, Martin Trøstheim, Kaja Buen, Eira Nordeng Jensen, Gernot Ernst, Siri Leknes, Marie Eikemo (*denotes equal contribution) https://osf.io/9kt3a?view_only=4238d2ee3d654c4f908a94efea82a027

Is childhood adversity associated with a heightened response to opioids?

Recommended by Chris Chambers based on reviews by Zoltan Dienes, Yuki Yamada and 1 anonymous reviewer

A convergence of evidence suggests that early life adversity may cause dysfunction in opioid-sensitive reward systems. Childhood adversity is associated with opioid use, potentially by altering reward and motivation networks, and experimental models in animals have found that early life adversity increases and consolidates opioid seeking behaviours. Further, in a recent controlled experiment, Carlyle et al. (2021) found that opioid administration produced stronger positive responses, and weaker negative responses, in adults with a history of childhood abuse and neglect.

In the current study, Carlyle et al. (2023) tested the generalisability of these previous findings in a pre-operative clinical setting. Using partially observed data from an existing cohort study (N=155), the authors asked whether patients with greater experience of childhood trauma in turn exhibit a larger mood boost and express greater subjective pleasure following opioid administration.

In contrast to previous findings, the results did not support the hypotheses that more experiences of childhood adversity would heighten ratings of drug liking and feeling good following opioid administration. Regression analyses instead revealed a statistically significant negative association between childhood adversity and post-opioid liking and no significant relationship with feeling good. The authors suggest that the discrepancy between the current and previous results may be due to stress related to the pre-surgical setting, the brief duration of drug exposure, and the relatively limited levels of high childhood adversity in the study sample. Nevertheless, these findings cast some doubt on the theory that adversity elevates risk of opioid addiction by altering sensitivity to subjectively pleasurable effects.

Following one round of in-depth review, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.

URL to the preregistered Stage 1 protocol: https://osf.io/7ymts

Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors prior to IPA, but the authors certify that they had not yet observed the key variables within the data that were used to answer the research question AND they took additional steps to maximise bias control and rigour.

List of eligible PCI RR-friendly journals:

References

1. Carlyle M., Broomby R., Simpson G., Hannon R., Fawaz L., Mollaahmetoglu O.M., Drain, J., Mostazir, M., & Morgan C. (2021). A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine. Addiction Biology, 26(6):e13047. https://doi.org/10.1111/adb.13047

2. Carlyle, M., Kvande, M., Meier, I. M., Trøstheim, M., Buen, K., Jensen, E. N., Ernst, G. & Leknes, S. & Eikemo, M. (2023). Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery, acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/9kt3a?view_only=4238d2ee3d654c4f908a94efea82a027

24 Oct 2022

STAGE 1

Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

Molly Carlyle*, Malin Kvande*, Siri Leknes, Isabell Meier, Kaja Buen, Eira Nordeng Jensen, Gernot Ernst, Marie Eikemo. *denotes equal contribution. https://osf.io/qcj5m?view_only=4238d2ee3d654c4f908a94efea82a027

Is childhood adversity associated with a heightened response to opioids?

Recommended by Chris Chambers based on reviews by Zoltan Dienes, Yuki Yamada and 1 anonymous reviewer

In the current study, Carlyle et al. seek to test the generalisability of these previous findings in a pre-operative clinical setting. Using partially observed data from an existing cohort study (N=155), the authors will test whether patients with greater experience of childhood trauma in turn exhibit a larger mood boost and express greater subjective pleasure following opioid administration. Although not a randomised experimental design, this study provides the opportunity to examine the relationship between opioid response and history of childhood adversity in a naturalistic setting, and thus has the potential to either support or cast doubt on the theory that adversity elevates risk of opioid addiction by altering sensitivity to subjectively pleasurable effects.

Following three rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/7ymts

Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question AND they have taken additional steps to maximise bias control and rigour.

List of eligible PCI RR-friendly journals:

References

2. Carlyle, M., Kvande, M., Leknes, S., Meier, I., Buen, K., Jensen, E. N., Ernst, G. & Eikemo, M. (2022). Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery, in principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/7ymts

YAMADA Yuki

Nusu Lab, Kyushu University, Fukuoka, Japan
Social sciences
recommender, manager

Recommendations: 6

Reviews: 2

Website https://sites.google.com/site/yamadayuk/

Areas of expertise