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IdTitleAuthorsAbstractPictureThematic fieldsRecommender▲ReviewersSubmission date
07 Dec 2023
STAGE 1
toto

Is conscious perception necessary to direct attention? A replication of Jiang et al. (2006)

Can sexually salient stimuli direct attention outside of conscious awareness?

Recommended by ORCID_LOGO based on reviews by Myron Tsikandilakis and Surya Gayet
Are attention and consciousness inherently intertwined or distinct aspects of cognition? One report (Jiang et al. 2006) presented clear results in evidence of the latter. In this earlier study, the authors used a continuous flash suppression (CFS) paradigm which presents a colorful pattern to the dominant eye and stimuli of interest to the non-dominant eye; the colorful pattern masks the relevant stimulus from awareness. On each trial, the authors presented a sexually stimulating image and a scrambled image on different sides of a computer screen during CFS. They found that, even though participants were not consciously aware of the images, intact images that matched participants' sexual orientation could still capture attention.
 
Despite these seemingly clear results, the authors of the current Stage 1 manuscript pointed out that CFS studies are often not replicated, and the paper by Jiang et al. (2006) is no exception. Therefore, Chen et al. (2023) seek to replicate this study using a Bayesian (rather than NHST) analytic approach. This method will allow the authors to determine the strength of evidence for their hypotheses.
 
In this Stage 1 manuscript, Chen et al. present an introduction that motivates the replication, and a pilot study that replicated the procedure of Jiang et al. (2006) conducted with 21 participants. This led to a well-motivated statistical sampling plan and some small design changes for the main experiment, such as adding a staircasing procedure to remove potential performance ceiling effects, and using less extreme wording for stimulus attractiveness ratings. A clear study design template is presented, detailing the different hypotheses that will be tested, and what different outcomes would indicate.
 
The Stage 1 submission was evaluated by the recommender and two expert reviewers. Following revisions, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/b2ncp
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 

References
 
1. Jiang, Y., Costello, P., Fang, F., Huang, M., & He, S. (2006). A gender-and sexual orientation-dependent spatial attentional effect of invisible images. Proceedings of the National Academy of Sciences, 103, 17048-17052. https://doi.org/10.1073/pnas.0605678103
 
2. Chen, Y.-J., Scott, R.B., & Dienes, Z. (2023). Is conscious perception necessary to direct attention? A replication of Jiang et al. (2006). In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/b2ncp
Is conscious perception necessary to direct attention? A replication of Jiang et al. (2006)Yung-Jung Chen, Ryan B Scott, Zoltan Dienes<p>The relationship between attention and consciousness has been debated for the past few decades. Observing attentional biases induced by visual stimuli below conscious threshold is one way of providing evidence for the independence of attention ...Social sciencesReshanne Reeder2023-10-11 22:02:33 View
24 Apr 2024
STAGE 1
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Synaesthesia as a Model for Assessing Individual Differences in Visual Perception and Memory Performance

What can synaesthesia tell us about links between perception and memory?

Recommended by ORCID_LOGO based on reviews by Janina Neufeld, David Brang and Tessa van Leeuwen
What is the relationship between perception and memory? Although these topics are typically investigated separately, there is evidence that these cognitive processes may be related: for example, individuals with synaesthesia may experience both enhancements in visual acuity and visual memory; and individuals with amnesia may also show deficits in visual perceptual processing. However, comprehensive evidence for the relationship between perception and different forms of memory (both short-term and long-term) is currently lacking.
 
In this Stage 1 manuscript, Whelan et al. (2024) seek to elucidate this relationship by investigating individual differences in perception and memory in a general population sample (i.e., in synaesthetes, non-synaesthetic relatives, and controls). There are two accounts that may explain enhanced perception and memory in synaesthesia: a ‘dual-coding’ account, which suggests that the extra perceptual information often experienced in synaesthesia (e.g., seeing colors for different letters of the alphabet) may contribute to encoding richer information in sensory memory; and an ‘enhanced processing’ account, which posits that enhanced perception and memory in synaesthesia may be due to genetic or environmental factors not directly related to synaesthetic experiences. In the former case, synaesthetes should perform more similarly to each other than to their non-synaesthetic relatives; in the latter case, non-synaesthetic relatives of synaesthetes should show similar perceptual and memory benefits. The current study should therefore find evidence in favor of one of these accounts over the other. In addition to this, the authors will generate multidimensional cognitive profiles of synaesthetes and their relatives, compared to non-synaethetes, including perception, memory, mental imagery and cognitive styles. 
 
The Stage 1 submission was evaluated by the recommender and two expert reviewers. Following revisions, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/6h8dx (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Whelan, E., Sachdeva, C., Ovalle-Fresa, R., Rothen R., & Ward, J. (2024). Synaesthesia as a Model for Assessing Individual Differences in Visual Perception and Memory Performance. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/6h8dx
Synaesthesia as a Model for Assessing Individual Differences in Visual Perception and Memory PerformanceEmily Whelan, Chhavi Sachdeva, Rebecca Ovalle-Fresa, Nicolas Rothen and Jamie Ward<p>In this study, the cognitive profile of synaesthesia (a perceptual condition in which primary experiences, such as perceiving digits or words, elicit extra secondary sensations) is used as a model system to assess visual perceptual abilities an...Social sciencesReshanne Reeder2023-11-07 13:02:39 View
11 Apr 2024
STAGE 1
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Do pain and effort increase prosocial contributions?: Revisiting the Martyrdom Effect with a Replication and extensions Registered Report of Olivola and Shafir (2013)

More pain, more prosocial? Assessing the Martyrdom Effect

Recommended by ORCID_LOGO based on reviews by Vanessa Clemens and Liesbeth Mann
The Martyrdom Effect is a behavioral tendency in which individuals exhibit greater generosity when their acts of giving entail effort or self-sacrifice (Olivola & Shafir, 2013). Giving at a personal cost, in this mindset, is associated with ascribing and inferring more meaning and value to charitable giving or other forms of generosity than in instances where no particular pain or effort is required to enact prosocial behavior. Arguably, the Martyrdom Effect’s ability to boost prosocial behavior therefore departs from other theories of behavior change postulating that easy options to act prosocially could boost contributions (e.g., default effects in charitable giving, see Altmann et al., 2019; Goswami & Urminsky, 2016). Because they introduce complexity to the debate about encouraging prosocial behavior, three studies from Olivola and Shafir (2013) are now being addressed in this Registered Report by Cheng and Feldman (2024).

Combining these three studies in a high-powered within-subjects replication attempt, transparently communicating necessary deviations from the original design and carefully outlining the analysis strategy, the current study will offer insights into the robustness of prior findings on the role of effort and pain in determining donations.

The Stage 1 manuscript was evaluated by two reviewers and the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/aq89u
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Altmann, S., Falk, A., Heidhues, P., Jayaraman, R., & Teirlinck, M. (2019). Defaults and Donations: Evidence from a Field Experiment. The Review of Economics and Statistics, 101, 808-826. https://doi.org/10.1162/rest_a_00774
 
2. Cheng, Y. T. & Feldman, G. (2024). Do pain and effort increase prosocial contributions?: Revisiting the Martyrdom Effect with a Replication and extensions Registered Report of Olivola and Shafir (2013). In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/aq89u
 
3. Goswami, I., & Urminsky, O. (2016). When should the Ask be a Nudge? The Effect of Default Amounts on Charitable Donations. Journal of Marketing Research, 53, 829-846. https://doi.org/10.1509/jmr.15.0001
 
4. Olivola, C. Y., & Shafir, E. (2013). The Martyrdom Effect: When Pain and Effort Increase Prosocial Contributions. Journal of Behavioral Decision Making, 26, 91-105. https://doi.org/10.1002/bdm.767
Do pain and effort increase prosocial contributions?: Revisiting the Martyrdom Effect with a Replication and extensions Registered Report of Olivola and Shafir (2013)Yim Tung (Emanuel) Cheng, Gilad Feldman<p>[IMPORTANT: Abstract, method, and results were written using a randomized dataset produced by Qualtrics to simulate what these sections will look like after data collection. These will be updated following the data collection. For the purpose o...Social sciencesRima-Maria Rahal Liesbeth Mann, Vanessa Clemens2023-11-30 12:32:25 View
14 Feb 2022
STAGE 1
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Minimal mindfulness of the world as an active control for a full mindfulness of mental states intervention: A Registered Report and Pilot study

Testing the metacognitive basis and benefits of mindfulness training

Recommended by ORCID_LOGO based on reviews by Chris Noone and Julieta Galante

Mindfulness is inherently metacognitive in that it requires monitoring of one’s own thoughts and attention in order to remain on task. Mindfulness practice is especially metacognitive when focused on internal mental states, rather than on the external world. This Registered Report will compare remote training in mindfulness of mental states with remote training in mindfulness of the world, and a wait list control, to test the idea that mindfulness of mental states has an additional metacognitive component, and that this has benefits for (self-reported) mental health. A comparison of participant expectancies between mindfulness conditions will be used to establish whether mindfulness of the world can be considered a true ‘active control’ condition. Additional comparisons will test whether this mindfulness control has benefits over the (inactive) waiting list condition. The study plan is informed by prior research, including pilot data presented in the Stage 1 report, and a sample of up to 300 participants will be tested.

The Stage 1 plan has been evaluated through two round of signed external review, and a further two rounds of minor revisions, with the recommender obtaining specialist advice on key points from a relevant external expert. The recommender has judged that the manuscript now meets all Stage 1 criteria, and has awarded In Principle Acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/tx54k

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly journals:

References

Lovell, M., & Dienes, Z. (2022). Minimal mindfulness of the world as an active control for a full mindfulness of mental states intervention: A Registered Report and Pilot study, in principle acceptance of version 4 by Peer Community in Registered Reports. https://osf.io/tx54k

Minimal mindfulness of the world as an active control for a full mindfulness of mental states intervention: A Registered Report and Pilot studyMax Lovell, Zoltan Dienes<p>Mindfulness is a continual renewal of non-elaborative attention on an object of focus, without clinging or aversion, and with equanimity. As this requires the capacity to monitor and control the extent to which one is on task, it is a metacogni...Social sciencesRobert McIntosh2021-06-21 16:49:39 View
21 Oct 2022
STAGE 1
toto

Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report

Testing the facilitatory effect of high-frequency transcranial random noise stimulation through enhancement of global motion processing

Recommended by ORCID_LOGO based on reviews by Sam Westwood and Filippo Ghin
High frequency transcranial random noise stimulation (hf-tRNS) is a relatively novel form of non-invasive brain stimulation, thought to enhance neural excitability and facilitate processing in targeted brain areas. The evidence for the efficacy of hf-tRNS is mixed, so a high-powered test of the proposed facilitatory effects would be of value to the field. This Registered Report will target the human middle temporal complex (hMT+), an area with a well-established critical role in global motion processing. The protocol is adapted from a study by Ghin and colleagues (2018) but focusing on a sub-set of the original experimental conditions and using a fully within-subjects design (n=42). Global motion processing will be operationalised in terms of the coherence threshold for identification of the dominant direction of random-dot motion. The experiment will test the predicted facilitation of contralateral motion processing (reduced coherence threshold) during hf-tRNS to the left hMT+. The specificity of this effect will be tested by comparison to a sham stimulation control condition and an active stimulation control condition (left forehead). By targeting a brain area with a well-established critical role in behaviour, this study will provide important information about the replicability and specificity of the facilitatory effects of hf-tRNS.
 
Following two rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).  
 
URL to the preregistered Stage 1 protocol: https://osf.io/bce7u
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Ghin, F., Pavan, A., Contillo, A., & Mather, G. (2018). The effects of high-frequency transcranial random noise stimulation (hf-tRNS) on global motion processing: an equivalent noise approach. Brain Stimulation, 11, 1263–75.
 
2. Caroll, M. B., Edwards, G. & Baker, C. I. (2022). Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report, in principle acceptance of Version 7 by Peer Community in Registered Reports. https://osf.io/bce7u
Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered reportMica B. Carroll*, Grace Edwards*, Chris I. Baker<p>Non-invasive brain stimulation (NIBS) techniques have the potential to demonstrate the causal impact of targeted brain regions on specific behaviors, and to regulate or facilitate behavior in clinical applications. Transcranial random noise sti...Life SciencesRobert McIntosh2022-06-02 21:25:02 View
27 Jun 2023
STAGE 1
toto

Functional MRI brain state occupancy in the presence of cerebral small vessel disease -- pre-registration for a replication analysis of the Hamburg City Health Study

Testing the replicability of dynamic functional connectivity correlates of cerebral small vessel disease in the Hamburg City Health Study

Recommended by ORCID_LOGO based on reviews by Olivia Hamilton and 1 anonymous reviewer
A recent study has reported that the extent of cerebral small vessel disease (cSVD) shows associations with dynamic functional connectivity measures obtained from resting state functional MRI scans (Schlemm et al, 2022). Specifically, when the functional scan was parsed into time spent in discrete brain states, the proportion of time spent in the two most-occupied states was negatively related to a structural indicator of cSVD (volume of white matter hyperintensities of presumed vascular origin). This measure of 'fractional occupancy' was also associated with cognitive impairment as indicated by longer time to complete part B of the Trail Making Test. These findings were based on the analysis of data from 988 participants in the Hamburg City Health Study (HCHS).
 
In the present Registered Report, Schlemm (2023) will test whether these associations can be replicated in an independent sample of participants from the HCHS, not included in the earlier analysis (projected N for new analysis ~1500). In addition to the two main hypothesis tests, an exploratory multiverse analysis will be reported, systematically varying some key parameters of the MRI processing pipeline to provide further information about the robustness of the outcome of the primary hypothesis test. 
 
The Stage 1 plan was refined over two rounds of review by two relevant experts, with additional input from the recommender on the specification of the registered plan. Both reviewers are satisfied that the plan constitutes an appropriate approach to this question, and on the basis of their comments and his own evaluation, the recommender judged that the Stage 1 report meets the criteria for in-principle acceptance.
 
URL to the preregistered Stage 1 protocol: https://osf.io/9yhzc
 
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question AND they have taken additional steps to maximise bias control and rigour.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Schlemm, E., Frey, B. M., Mayer, C., Petersen, M., Fiehler, J., Hanning, U., Kühn, S., Twerenbold, R., Gallinat, J., Gerloff, C., Thomalla, G. & Cheng, B. (2022). Equalization of brain state occupancy accompanies cognitive impairment in cerebral small vessel disease. Biological Psychiatry, 92, 592-602. https://doi.org/10.1016/j.biopsych.2022.03.019
 
2. Schlemm, E. (2023). Functional MRI brain state occupancy in the presence of cerebral small vessel disease – pre-registration for a replication analysis of the Hamburg City Health Study. In principle acceptance of Version 1.5 by Peer Community in Registered Reports. https://osf.io/9yhzc
Functional MRI brain state occupancy in the presence of cerebral small vessel disease -- pre-registration for a replication analysis of the Hamburg City Health StudyEckhard Schlemm<p>Objective: To replicate recent findings about the association between the extent of cerebral small vessel disease (cSVD), functional brain network dedifferentiation and cognitive impairment.</p> <p>Methods: We will analyze demographic, imaging...Life Sciences, Medical SciencesRobert McIntosh2022-11-19 14:21:28 View
28 Nov 2023
STAGE 1
toto

One and only SNARC? A Registered Report on the SNARC Effect’s Range Dependency

Is the SNARC effect modulated by absolute number magnitude?

Recommended by ORCID_LOGO based on reviews by Melinda Mende and 1 anonymous reviewer
The Spatial-Numerical Association of Response Codes (SNARC) effect refers to the fact that smaller numbers receive faster responses with the left hand, and larger numbers with the right hand (Dehaene et al., 1993). This robust finding implies that numbers are associated with space, being represented on a mental number line that progresses from left to right. The SNARC effect is held to depend on relative number magnitude, with the mental number line dynamically adjusting to the numerical range used in a given context. This characterisation is based on significant effects of relative number magnitude, with no significant influence of absolute number magnitude. However, a failure to reject the null hypothesis, within the standard frequentist statistical framework, is not firm evidence for the absence of an effect. In this Stage 1 Registered Report, Roth and colleagues (2023) propose two experiments adapted from Dahaene’s (1993) original methods, with a Bayesian statistical approach to confirm—or rule out—a small effect (d = 0.15) of absolute number magnitude in modulating the classic SNARC effect.
 
The study plan was refined across two rounds of review, with input from two external reviewers and the recommender, after which it was judged to satisfy the Stage 1 criteria for in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/ae2c8
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Dehaene, S., Bossini, S., & Giraux, P. (1993). The mental representation of parity and number magnitude. Journal of Experimental Psychology: General, 122(3), 371–396. https://doi.org/10.1037/0096-3445.122.3.371
 
Roth, L., Caffier, J., Reips, U.-D., Nuerk, H.-C., & Cipora, K. (2023). One and only SNARC? A Registered Report on the SNARC Effect’s Range Dependency. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/ae2c8
One and only SNARC? A Registered Report on the SNARC Effect’s Range DependencyLilly Roth, John Caffier, Ulf-Dietrich Reips, Hans-Christoph Nuerk, Krzysztof Cipora<p>Numbers are associated with space, but it is unclear how flexible these associations are. In this study, we will investigate whether the SNARC effect (Spatial-Numerical Association of Response Codes; Dehaene et al., 1993), which describes faste...Social sciencesRobert McIntosh2022-11-30 12:36:08 View
08 Sep 2023
STAGE 1
toto

Evaluation of spatial learning and wayfinding in a complex maze using immersive virtual reality. A registered report

Evaluation of an immersive virtual reality wayfinding task

Recommended by ORCID_LOGO based on reviews by Conor Thornberry, Gavin Buckingham and 1 anonymous reviewer
The Virtual Maze Task (VMT) is a digital desktop 2D spatial learning task that has been used for research into the effect of sleep and dreaming on memory consolidation (e.g. Wamsley et al, 2010). One limitation of this task has been low rates of reported dream incorporation. Eudave and colleagues (2023) have created an immersive virtual reality (iVR) version of the VMT, which they believe might be more likely to be incorporated into dreams. As an initial step in validating this task for research, they propose a within-subjects study to compare three measures of spatial learning between the 2D desktop and iVR versions. Based on a review of relevant literature, the prediction is that performance will be similar between the two task versions. The planned sample size (n = 62) is sufficient for a .9 power test of equivalence within effect size bounds of d = -.47 to .47. Additional independent variables (gender, perspective-taking ability) and dependent measures (self-reported cybersickness and sense of presence) will be recorded for exploratory analyses.
 
The study plan was refined across four rounds of review, with input from two external reviewers and the recommender, after which it was judged to satisfy the Stage 1 criteria for in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/wba2v
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Eudave, L., Martínez, M., Valencia, M., & Roth D. (2023). Evaluation of spatial learning and wayfinding in a complex maze using immersive virtual reality. A registered report. In principle acceptance of Version 5 by Peer Community in Registered Reports.
 
Wamsley, E. J., Tucker, M., Payne, J. D., Benavides, J. A., & Stickgold, R. (2010). Dreaming of a learning task is associated with enhanced sleep-dependent memory consolidation. Current Biology, 20, 850–855. https://doi.org/10.1016/j.cub.2010.03.027
 
† There is one minor change that the authors should make to the Methods section, which is sufficiently small that it can be incorporated at Stage 2: "if both tests reject the null hypothesis (observed data is less/greater than the lower/upper equivalence bounds), conditions are considered statistically equivalent" >> suggest changing "less/greater" to "greater/lesser" for correct correspondence with "lower/upper".
Evaluation of spatial learning and wayfinding in a complex maze using immersive virtual reality. A registered reportEudave L., Martínez M., Valencia M., Roth D.<p style="text-align: justify;"><strong>Objectives</strong>: Mazes have traditionally been used as tools for evaluating spatial learning and navigational abilities in humans. They have been also utilized in sleep and dream research, as wayfinding ...Life SciencesRobert McIntosh2023-03-31 17:21:20 View
05 Feb 2024
STAGE 2
(Go to stage 1)
toto

Functional MRI brain state occupancy in the presence of cerebral small vessel disease -- a pre-registered replication analysis of the Hamburg City Health Study

Replicable dynamic functional connectivity and cognitive correlates of cerebral small vessel disease in the Hamburg City Health Study

Recommended by ORCID_LOGO based on reviews by 1 anonymous reviewer
In a previous analysis of data from 988 participants in the Hamburg City Health Study (HCHS), Schlemm and colleagues (2022) reported significant associations between the extent of cerebral small vessel disease (cSVD) and dynamic functional connectivity measures from resting state fMRI. Specifically, the volume of white matter hyperintensities of presumed vascular origin, a structural indicator of cSVD, was negatively related to the proportion of time (‘fractional occupancy’) spent in the two most occupied functional brain states. Reduced fractional occupancy was also associated with longer times to complete part B of the Trail Making Test.
 
In the present Registered Report, Ingwersen and colleagues (2023) successfully replicated these associations between structural, functional and cognitive measures in a sample of 1651 HCHS participants not included in the earlier study. An exploratory multiverse analysis found that the associations were generally robust to different brain parcellation and confound regression strategies. These replicable patterns reinforce the idea that cSVD may disrupt the brain’s ability to enter and maintain distinct functional modes, and that these changes in functional dynamics are predictive of cognitive impairment.
 
The Stage 2 manuscript was assessed over one round of in-depth review. The recommender judged that responses to reviewer comments were appropriate, and that the manuscript met the Stage 2 criteria for recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/9yhzc
 
Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors prior to Stage 1 in-principle acceptance, but the authors certify that they had not yet observed the key variables within the data that were used to answer the research question AND they took additional steps to maximise bias control and rigour.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Schlemm, E., Frey, B. M., Mayer, C., Petersen, M., Fiehler, J., Hanning, U., Kühn, S., Twerenbold, R., Gallinat, J., Gerloff, C., Thomalla, G. & Cheng, B. (2022). Equalization of brain state occupancy accompanies cognitive impairment in cerebral small vessel disease. Biological Psychiatry, 92, 592-602. https://doi.org/10.1016/j.biopsych.2022.03.019
 
2. Ingwersen, T., Mayer, C., Petersen, M., Frey, B. M., Fiehler, J., Hanning, U., Kühn, S., Gallinat, J., Twerenbold, R., Gerloff, C., Cheng, B., Thomalla, G. & Schlemm, E. (2023). Functional MRI brain state occupancy in the presence of cerebral small vessel disease -- a pre-registered replication analysis of the Hamburg City Health Study. Acceptance of Version 2.01 by Peer Community in Registered Reports. https://github.com/csi-hamburg/HCHS-brain-states-RR/blob/f9d00adbbcf9593d8d191bf5b93912141b80ab1b/manuscript/build/main.pdf
 
Functional MRI brain state occupancy in the presence of cerebral small vessel disease -- a pre-registered replication analysis of the Hamburg City Health StudyThies Ingwersen, Carola Mayer, Marvin Petersen, Benedikt M. Frey, Jens Fiehler, Uta Hanning, Simone Kühn, Jürgen Gallinat, Raphael Twerenbold, Christian Gerloff, Bastian Cheng, Götz Thomalla, Eckhard Schlemm, <p><strong>Objective</strong>: To replicate recent findings on the association between the extent of cerebral small vessel disease (cSVD), functional brain network dedifferentiation, and cognitive impairment.</p> <p><strong>Methods:</strong> We a...Life Sciences, Medical SciencesRobert McIntosh2023-10-17 09:53:02 View
20 Apr 2023
STAGE 1
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Oxytocin, individual differences, and trust game behavior: a registered large-scale replication

Does oxytocin enhance pro-social behaviors?

Recommended by ORCID_LOGO based on reviews by Thibaut Arpinon and 1 anonymous reviewer
Trust is a fundamental element for the well-functioning of our society. By achieving large levels of trust, societies can reduce monitoring costs (e.g., contract supervision, conflict resolution) and increase investments in more profitable but socially riskier projects. Trust serves as a way to foster cooperation among individuals and can benefit the entire social group.
 
As a result, numerous researchers have sought to explore the biological foundations of trust. In particular, several research teams have tried to explore the role of oxytocin in modulating prosocial behaviors. However, previous research findings obtained mixed findings, and several methodological issues, such as low statistical power, have hindered the development of a definite view on the matter.
 
In the current study, Kroll et al. (2023) seek to replicate the seminal study of Kosfeld et al. (2005). Kosfeld and co-authors originally found that the intranasal administration of oxytocin can significantly increase trust among individuals. However, recent replication evidence shows no general effect of oxytocin on pro-social behaviors or suggests that the effect might be heterogeneous among social groups (Declerck et al., 2020). The objective of the current study of Kroll et al. (2023) is twofold. First, the authors propose to replicate the original study of Kosfeld et al. (2005) and to investigate whether the lack of replication can be due to an overall effect that is smaller than the original findings suggest. Second, the authors propose to replicate recent but exploratory results on the heterogeneous effect of oxytocin on pro-social choices. 
 
The Stage 1 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/h5gdp
 
Level of bias control achieved: Level 4. At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors (e.g. residing in a public database or with a colleague) BUT the authors certify that they have not yet accessed any part of that data/evidence.
 
List of eligible PCI RR-friendly journals:
 
 
References:
 
1. Declerck, C. H., Boone, C., Pauwels, L., Vogt, B., & Fehr, E. (2020). A registered replication study on oxytocin and trust. Nature Human Behaviour, 4(6), 646–655. https://doi.org/10.1038/s41562-020-0878-x
 
2. Kosfeld, M., Heinrichs, M., Zak, P. J., Fischbacher, U., & Fehr, E. (2005). Oxytocin increases trust in humans. Nature, 435(7042), 673–676. https://doi.org/10.1038/nature03701
 
3. Kroll, C. F., Schruers, K., Viechtbauer, W., Vingerhoets, C., Seidel, L., Riedl, A. & Hernaus, D. (2023). Oxytocin, individual differences, and trust game behavior: a registered large-scale replication, in principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/h5gdp
Oxytocin, individual differences, and trust game behavior: a registered large-scale replicationCharlotte F. Kroll, Koen Schruers, Wolfgang Viechtbauer, Claudia Vingerhoets, Leonie Seidel, Arno Riedl, and Dennis Hernaus<p>The neuropeptide oxytocin (OXT) is thought to modulate important aspects of prosocial behavior. In a seminal paper, Kosfeld et al. (2005) reported that intranasally administered OXT modulated trusting behavior in an economic trust game. Several...Life Sciences, Social sciencesRomain Espinosa2022-11-25 18:07:23 View