The Importance of Long- and Short-Acting Pharmacological Treatment Options for Time Use and Quality of Life in Individuals with Opioid Use Disorder: An Observational, Cross-Sectional, Survey-Based Studyuse asterix (*) to get italics

Martin Trøstheim, Siri Leknes, Kristin K. Solli, Molly Carlyle, Gernot Ernst, Marie EikemoPlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"

2024

<p><strong>Background. </strong>Pharmacological treatment for opioid use disorder with new, long-acting medications (e.g., injectable and implantable buprenorphine) frees up a considerable amount of patients’ time otherwise spent seeking illicit opioids or collecting daily opioid substitution medications. How much of this time patients treated with long-acting medications spend on activities related to recovery, substance use, and treatment is however currently unclear. Based on patients’ hopes for and concerns about long-acting medications, we hypothesized that there is a relationship between medication type and time use, and between time use and well-being, experienced stigma and life satisfaction, in individuals with opioid use disorder.</p> <p><strong>Methods. </strong>In this cross-sectional study, individuals with opioid use disorder completed a short survey about their treatment status, time use, and experience of well-being, experienced stigma and life satisfaction. Latent profile analysis was used to identify common time use profiles among the participants. Next, we modeled the relationship between medication type and time use profile, and between time use profile and well-being, experienced stigma and life satisfaction with multinomial and ordinal logistic regression, respectively. We also used multimodel inference to identify the most important aspects of time use for predicting well-being, experienced stigma and life satisfaction.</p>

Opioid use disorder; Opioid substitution treatment; Time use; Quality of life; Observational study; Survey

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Medical Sciences, Social sciences

Cathy Montgomery suggested: Joanne Neale , Cathy Montgomery suggested: Walter Ling

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2024-06-28 11:11:22

Andrew Jones

Cathy Montgomery, Chris Chambers