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The Importance of Long- and Short-Acting Pharmacological Treatment Options for Time Use and Quality of Life in Individuals with Opioid Use Disorder: An Observational, Cross-Sectional, Survey-Based Studyuse asterix (*) to get italics
Martin Trøstheim, Siri Leknes, Kristin K. Solli, Molly Carlyle, Gernot Ernst, Marie EikemoPlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"
2024
<p><strong>Background. </strong>Pharmacological treatment for opioid use disorder with new, long-acting medications (e.g., injectable and implantable buprenorphine) frees up a considerable amount of patients’ time otherwise spent seeking illicit opioids or collecting daily opioid substitution medications. How much of this time patients treated with long-acting medications spend on activities related to recovery, substance use, and treatment is however currently unclear. Based on patients’ hopes for and concerns about long-acting medications, we hypothesized that there is a relationship between medication type and time use, and between time use and well-being, experienced stigma and life satisfaction, in individuals with opioid use disorder.</p> <p><strong>Methods. </strong>In this cross-sectional study, individuals with opioid use disorder completed a short survey about their treatment status, time use, and experience of well-being, experienced stigma and life satisfaction. Latent profile analysis was used to identify common time use profiles among the participants. Next, we modeled the relationship between medication type and time use profile, and between time use profile and well-being, experienced stigma and life satisfaction with multinomial and ordinal logistic regression, respectively. We also used multimodel inference to identify the most important aspects of time use for predicting well-being, experienced stigma and life satisfaction.</p>
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Opioid use disorder; Opioid substitution treatment; Time use; Quality of life; Observational study; Survey
NonePlease indicate the methods that may require specialised expertise during the peer review process (use a comma to separate various required expertises).
Medical Sciences, Social sciences
Cathy Montgomery suggested: Joanne Neale , Cathy Montgomery suggested: Walter Ling
e.g. John Doe john@doe.com
No need for them to be recommenders of PCI Registered Reports. Please do not suggest reviewers for whom there might be a conflict of interest. Reviewers are not allowed to review preprints written by close colleagues (with whom they have published in the last four years, with whom they have received joint funding in the last four years, or with whom they are currently writing a manuscript, or submitting a grant proposal), or by family members, friends, or anyone for whom bias might affect the nature of the review - see the code of conduct
e.g. John Doe john@doe.com
2024-06-28 11:11:22
Andrew Jones
Chris Chambers, Cathy Montgomery