Single gene alterations have been estimated to account for nearly half of neurodevelopmental conditions (NDCs), providing a crucial opportunity for animal models to understand the underlying mechanisms, causes and potential treatments. The use of systematic reviews (SRs) can, in principle, provide a powerful means to synthesise this evidence-base; however, the reporting quality of previous SRs in preclinical animal research has been found lacking (Hunniford et al., 2021). In the current study, Wilson et al. (2023) will undertake an umbrella review – a systematic review of systematic reviews – to assess the characteristics and reporting quality of SRs that, in turn, synthesise research in genetically-modified animals to model NDCs. In particular, the authors will extract key features of reviews (including, among others, the aim and primary research questions, relevant animal model, and number of studies in the SR), in addition to quality indicators such as risk of bias and completeness of reporting. In doing so, the authors aim to enhance guidance on the conduct and reporting of systematic reviews in this area.

 

The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/952qk

 

Level of bias control achieved: Level 4. At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors BUT the authors certify that they have not yet accessed any part of that data/evidence.

 
List of eligible PCI RR-friendly journals:

 

 

1. Hunniford V. T., Montroy J., Fergusson D. A., Avey M. T., Wever K. E., McCann S. K., Foster M., Fox G., Lafreniere M., Ghaly M., Mannell S., Godwinska K., Gentles A., Selim S., MacNeil J., Sikora L., Sena E. S., Page M. J., Macleod M., Moher D., & Lalu M. M. (2021). Epidemiology and reporting characteristics of preclinical systematic reviews. PLOS Biology, 19:e3001177. https://doi.org/10.1371/journal.pbio.3001177

 

2. Wilson, E., Currie, G., Macleod, M., Kind, P. & Sena, E. S. (2023). Genetically-modified animals as models of neurodevelopmental conditions: an umbrella review, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/952qk

For centuries, the ubiquity of language and music across human societies has prompted scholars to speculate about their cross-cultural origins as well as their shared and unique characteristics. Depending on the extent to which contemporary theories emphasise the role of biology vs. culture, a range of hypotheses have been proposed concerning expected similarities and differences in song and speech. One class of hypotheses stemming from cultural relativism assumes a lack of universal regularities in song and speech, and therefore predicts no systematic cross-cultural relationships. On the other hand, more recent evolutionary hypotheses such as the social bonding hypothesis, motor constraint hypothesis, and sexual selection hypothesis all predict differences or similarities in specific characteristic of vocalisations, such as pitch regularity, pitch interval size, and melodic contour. Existing results are mixed in their support of these predictions.

 

In the current study, Ozaki et al. (2023) elucidated cross-cultural similarities and differences between speech and song in 75 different linguistic varieties spanning 21 language families. Understanding precisely how song and speech are related is methodologically challenging due to the multitude of confounds that can arise in comparing natural recordings. Here the authors overcame these difficulties with four types of carefully controlled recordings: singing, recitation of sung lyrics, spoken description of the song, and instrumental version of the sung melody. The authors then examined six features that are amenable to reliable comparison, including pitch height, temporal rate, pitch stability, timbral brightness, pitch interval size, and pitch declination. With this data in hand, the authors asked which acoustic features differ reliably between song and speech across cultures, with the expectation that song would exhibit higher pitch, slower rate and more stable pitch than speech. At the same time, the authors expected song and speech to be reliably similar in the characteristics of timbral brightness, pitch intervals and pitch contours

 

The findings provided strong support for the preregistered hypotheses. Relative to speech, songs exhibited higher pitch, slower temporal rate, and more stable pitches, while both songs and speech had similar pitch interval size and timbral brightness. Only one hypothesis was unsupported, with the comparison of pitch declination between song and speech turning out inconclusive. To overcome potential sources of analytic bias, the authors undertook additional robustness checks, including reanalysis of a previously published dataset of over 400 song/speech recordings; this exploratory analysis corroborated the conclusions from the confirmatory analysis. Overall this study offers a unique insight into the shared global characteristics of langage and music, with implications for understanding their cultural and biological (co)evolution.

 

The Stage 2 manuscript was evaluated over one round of in-depth review. Based on responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and therefore awarded a positive recommendation.

 

 

Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors, but the authors certify that they had not yet observed the key variables within the data that were be used to answer the research question AND they took additional steps to maximise bias control and rigour.

 

 

 

1. Ozaki, Y. et al. (2023). Globally, songs and instrumental melodies are slower, higher, and use more stable pitches than speech [Stage 2 Registered Report]. Acceptance of Version 11 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/jr9x7

Ensuring universal access to sexual and reproductive health and reproductive rights is a global concern, exemplified by goal 5.6 of the Sustainable Development Goals (UN General Assembly, 2015). Whilst the range of contraceptive options have increased, our understanding of the impacts of use for women are inadequate and represent a key barrier to positive change in policies and practices. In particular, we have few consensuses on the expected impacts of hormonal contraceptive use on women's sexuality and wellbeing.

 

In the current programmatic submission, Botzet et al. (2023) argue that this inconclusive evidence base could be due to the wide heterogeneity in responses, the impacts of this heterogeneity upon attrition, differences in contraceptive methods and dosage effects, confounders, and the potential for reverse causality. Tackling some of these potential factors, Botzet (2023) explore whether hormonal contraceptive use influences sexuality and well-being outcomes, and whether (and to what extent) the effects vary between women. To achieve this they have proposed analysis of longitudinal data from the German Family Panel (PAIRFAM) which includes annual waves of data collection from >6500 women, with separate Stage 2 submissions planned to report findings based on sexuality and well-being. The proposed work will progress our understanding of the impact of hormonal contraceptives by overcoming limitations of more common research approaches in this field, and has the potential to contribute to a more contextualised view of the impact of their impacts in real-world practice.

 

The Stage 1 manuscript was evaluated over three rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

 

 

Level of bias control achieved: Level 3: At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors BUT the authors certify that they have not yet accessed any part of that data/evidence.

 

 

• Collabra: Psychology
• Peer Community Journal
• PeerJ
• Royal Society Open Science
• Studia Psychologica
• Swiss Psychology Open
  
  

 

Botzet, L. J., Rohrer, J. M., Penke, L. & Arslan, R. C. (2023). Hormonal Contraceptive Use and Women's Sexuality and Well-Being: Estimating Treatment Effects and Their Heterogeneity Based on Longitudinal Data. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/kj3h2

 

UN General Assembly (2015). Transforming our world : the 2030 Agenda for Sustainable Development, 21 October 2015, A/RES/70/1. Available at: https://www.refworld.org/docid/57b6e3e44.html [accessed 27 September 2023]

Many products that can impact upon health and wellbeing (e.g., alcohol, food) relay information to consumers about the potential risks. However, such information is commonly provided in suboptimal format for gambling-related products. To encourage safer gambling, research has therefore recommended that information about the average loss from a gambling product (“house edge”) or percentage payout (“return-to-player”) should be communicated, with the former translating to better perceived understanding by gamblers. This Registered Report aimed to experimentally compare two phrasings of the house edge against a control return-to-player to arrive at the most effective phrasing to aid gambler’s perceived chances of winning and their factual understanding of the statistical outcomes of their bet. Using a hypothetical gambling scenario, a sample of 3,333 UK-based online gamblers received one of three phrasings: an original house-edge (“his game keeps 10% of all money bet on average”), an alternative house-edge (“on average this game is programmed to cost you 10% of your stake on each bet”) or return-to-player (“this game has an average percentage payout of 90%”). Two outcome measures were employed to judge the effectiveness of this information: gamblers’ perceived changes of winning and factual understanding. The findings indicate that the two-house edge formats were more effective in communicating gambling-related harms than the return-to-player format, but the original house edge phrasing appeared to be the most optimal as it decreased gambler’s perceived chances of winning and increased their factual understanding compared to return-to-player. These results can therefore inform public health policies to reduce gambling-related harm by presenting the most effective communication of gambling risk.

 

After two in-depth reviews, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.

 

URL to the preregistered Stage 1 protocol: https://osf.io/5npy9
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 

References
  
1. Newall, P. W. S., James, R. J. E. & Maynard, O. M. (2023). How does the phrasing of house edge information affect gamblers’ perceptions and level of understanding? A Registered Report. Acceptance of Version 2 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/pfnzd

Research on interviewing has often focused on topics (such as aiding memory of witnesses) which presume the interviewee has already correctly identified the precise information that the interviewer is really after. But how does an informant know what sort of information is asked for, a precondition for an informant to then choose to provide the information or withhold it (depending on their own interests)?

 
In this study, Neequaye and Lorson will ask subjects to take the role of an informant about a criminal gang, with the further instructions to be cooperative or resistant in helping the interviewer obtain the information they want. In one study, the participants will be asked merely to identify what information the interviewer wants. In the second study, the participants will answer the interviewer's questions, disclosing whatever information they feel best suits their interest. Crucially, the level of detail of the questions will be manipulated, such that the question specifies a clear objective or not.

The Stage 1 manuscript was evaluated over three rounds of in-depth review. Based on detailed responses to the reviewers’ comments and edits to the stage 1 report, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/82qtn
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:

 

 

 

1. Neequaye, D. A., & Lorson, A. (2022). How Intelligence Interviewees Mentally Identify Relevant Information, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/82qtn