Cortical voice processing in Autism Spectrum Disorderuse asterix (*) to get italics

Raphaël Gautier, Emmanuelle Houy-Durand, Laurent Barantin, Frederic Briend, Marianne LatinusPlease use the format "First name initials family name" as in "Marie S. Curie, Niels H. D. Bohr, Albert Einstein, John R. R. Tolkien, Donna T. Strickland"

2023

<p>Voice processing is central to social functioning. A specific brain response to vocal sounds has been described and extensively characterized in the general population but remains critically unexplored in Autism Spectrum Disorder (ASD), a condition mainly characterized by social difficulties. The few studies conducted within the ASD population reported contradictory results with either a lack of or a typical brain response to vocal sounds in ASD. Hence, it is not clear whether at least some ASD individuals are characterized by a dysfunctional response to vocal sounds and if the discrepancies between the studies are due to sample characteristics. This registered report aims to characterize the individual brain response to vocal sounds, for ASD (n=26) and non-ASD (n=26) individuals using an fMRI block-design study contrasting vocal with non-vocal sounds. The proportion of individuals showing a specific response to vocal sounds will be compared between groups. We hypothesize a lower proportion of individuals showing a specific response to vocal sounds in the ASD group. Results from this study might resolve the discrepancies between the results described in the literature.</p>

Voice processing, Autism Spectrum Disorder, Temporal Voice Areas, fMRI

NonePlease indicate the methods that may require specialised expertise during the peer review process (use a comma to separate various required expertises).

Life Sciences

Daniela Sammler [sammler@cbs.mpg.de] suggested: Jens Kreitewolf (Lübeck), Katharina von Kriegstein (Dresden), Sascha Frühholz (Zürich/Oslo), Jens Kreitewolf [jens.kreitewolf@mcgill.ca] suggested: Unfortunately, I have to decline the review request at this time. I suggest my former colleague Dr. Stefanie Schelinski (stefanie.schelinski@​tu-dresden.de) as a suitable reviewer for this article., Trevor Agus [t.agus@qub.ac.uk] suggested: I would recommend Pascal Belin pascal.belin@univ-amu.fr or any of his co-authors. , Trevor Agus [t.agus@qub.ac.uk] suggested: Deborah Hall Deborah.Hall@hw.ac.uk has a long history of auditory fMRI studies. , Trevor Agus [t.agus@qub.ac.uk] suggested: Otherwise, Daniel Pressnitzer <daniel.pressnitzer@gmail.com> could be willing, even though he is not an fMRI specialist. , Trevor Agus [t.agus@qub.ac.uk] suggested: Apologies for declining—although I ended up first-authoring an fMRI paper close to this, I am more familiar with cognitive psychological methods. No need for them to be recommenders of PCI Registered Reports. Please do not suggest reviewers for whom there might be a conflict of interest. Reviewers are not allowed to review preprints written by close colleagues (with whom they have published in the last four years, with whom they have received joint funding in the last four years, or with whom they are currently writing a manuscript, or submitting a grant proposal), or by family members, friends, or anyone for whom bias might affect the nature of the review - see the code of conduct

2023-03-28 09:51:48

Grace Edwards