Submit a report

Announcements

We are recruiting recommenders (editors) from all research fields!

Your feedback matters! If you have authored or reviewed a Registered Report at Peer Community in Registered Reports, then please take 5 minutes to leave anonymous feedback about your experience, and view community ratings.


 

Latest recommendationsrssmastodon

IdTitleAuthors▼AbstractPictureThematic fieldsRecommenderReviewersSubmission date
22 Oct 2023
STAGE 1
toto

Michotte's research on perceptual impressions of causality: a pre-registered replication study

Gaining confidence in Michotte’s classic studies on the perception of causality

Recommended by ORCID_LOGO based on reviews by Maxine Sherman and 1 anonymous reviewer
​​​Making causal judgements are part of everyday life, whether seeking to understand the action of complex humans or the relations between inanimate objects in our environments. Albert Michotte’s (1963) classic book, The perception of causality, contained an extensive report of experiments demonstrating not only that observers perceive causality of inanimate shapes, but do so in manifold ways, creating different “causal impressions.” This work has been highly influential across psychology and neuroscience.
 
In the current study, White (2023) proposes a series of experiments to replicate and extend Michotte’s work. Despite the fact that this research is foundational to current work on perception and understanding of causal relations, it has never been subjected to rigorous replication. Moreover, like many research studies from that era, Michotte was sparse on details about methodology and did not rely on statistical analysis. White has proposed an ambitious set of 14 experiments that directly replicate and, in some cases, extend Michotte’s experiments. 
 
The Stage 1 manuscript was evaluated over three rounds of in-depth review, the first two rounds consisting of detailed comments from two reviewers and the third round consisting of a close read by the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and was therefore awarded in-principle acceptance (IPA). 
 
URL to the preregistered Stage 1 protocol: https://osf.io/5jx8f (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI-RR-friendly journals:
 
 
References
 
1. Michotte, A. (1963). The perception of causality (T. R. Miles & E. Miles, trans.). London: Methuen. (English translation of Michotte, 1954).
 
2. White, P. A. (2023). Michotte's research on perceptual impressions of causality: A registered replication study. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/5jx8f 
Michotte's research on perceptual impressions of causality: a pre-registered replication studyPeter A. White<p>&nbsp; &nbsp; &nbsp; &nbsp; &nbsp; &nbsp; Michotte (1946/1954/1963) showed that visual impressions of causality can occur in perception of simple animations of moving geometrical objects. In the launching effect, one object is perceived as maki...Life Sciences, Social sciencesMoin Syed2023-05-03 13:04:00 View
18 Jul 2023
STAGE 1
toto

Test-Retest Reliability of the STRAQ-1: A Registered Report

A reliable measure of physical closeness in interpersonal relationships?

Recommended by ORCID_LOGO based on reviews by Jacek Buczny and Ian Hussey
Attachment and interpersonal relationships are a major subject of research and clinical work in psychology. There are, accordingly, a proliferation of measurement instruments to tap into these broad constructs. The emphasis in these measures tends to be on the emotional dimensions of the relationships—how people feel about their partners and the support that they receive. However, that is not all there is to relationship quality. Increasing attention has been paid to the physical and physiological aspects of relationships, but there are few psychometrically sound measures available to assess these dimensions.
 
In the current study, Dujols et al. (2023) seek to assess the psychometric properties of the Social Thermoregulation and Risk Avoidance Questionnaire (STRAQ-1), a measure of physical relationships that targets social thermoregulation, or how physical proximity is used to promote warmth and closeness. The proposed project will be a thorough assessment of the measure’s reliability over time—that is, the degree to which the measure assesses the construct similarly across administrations. The authors will assess the test-retest reliability and longitudinal measurement invariance of the STRAQ-1, providing much-needed psychometric data that can build confidence in the utility of the measure.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review, the first round consisting of detailed comments from two reviewers and the second round consisting of a close read by the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and was therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/pmnk2
 
Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Dujols, O., Klein, R. A., Lindenberg, S., Van Lissa, C. J., & IJzerman, H. (2023). Test-Retest Reliability of the STRAQ-1: A Registered Report. In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/pmnk2
Test-Retest Reliability of the STRAQ-1: A Registered ReportOlivier Dujols; Richard A. Klein; Siegwart Lindenberg; Hans IJzerman<p>This Registered Report provides the first test of measurement invariance across time points and estimates of test-retest reliability for the Social Thermoregulation, Risk Avoidance Questionnaire (STRAQ-1, Vergara et al., 2019). The scale was de...Social sciencesMoin Syed2023-03-01 16:07:17 View
21 May 2023
STAGE 2
(Go to stage 1)
toto

Sunk cost effects for time versus money: Replication and extensions Registered Report of Soman (2001)

Mixed evidence for the hypothesis that sunk cost effects are weaker for time than money

Recommended by ORCID_LOGO based on reviews by Christopher Olivola and Dilip Soman
The sunk cost fallacy is a cognitive bias in which people persist with a decision that is no longer optimal because of previous resources they have invested (now considered to be spent or “sunk”). Most of us will have heard sunk costs reflected in the saying “throwing good money after bad”, but sunk costs can, in theory, occur more broadly, whether for money, time or any other resource-limited investment. The sunk cost effect for money has been widely studied and appears robust; in contrast, the sunk cost effect for time is more uncertain, and is potentially moderated by the age of respondents (and likely resource availability), the fact that time is irreplaceable, and the tendency for people to account for time less easily than they do for money. In an impactful study, Soman (2001) found that the sunk cost effect for time was indeed weaker than for money, although this finding has not been widely replicated.
 
In the current study, Petrov et al. (2023) replicated three studies (1, 2 and 5) from Soman (2001), asking whether sunk costs are weaker for time than for money, and then testing whether the relative absence of a sunk time cost arises from the inability of participants to account for time or due to more rational beliefs in the evaluation of past time investments.
 
Results provided mixed support for the original findings. Consistent with Soman (2001), the sunk cost effect for money was reliably stronger than for time in Study 1; however, sunk costs for both money and time were comparable in Study 2 (and if anything, slightly stronger for time). The indirect replication of Study 5 from Soman (2001) found that the sunk cost effect for time was not significantly influenced by accounting for time, either using education or by highlighting opportunity costs. Robustness checks confirmed the main preregistered outcomes while also ruling out a range of potential alternative explanations. Overall, the results suggest that that sunk cost effects for time are more context-dependent and empirically volatile than sunk costs for money.
 
URL to the preregistered Stage 1 protocol: https://osf.io/65htv
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Soman, D. (2001). The mental accounting of sunk time costs: Why time is not like money. Journal of Behavioral Decision Making,14, 169-185. https://doi.org/10.1002/bdm.370
 
2. Petrov, N. B., Chan, Y. K., Lau, C. N., Kwok, T. H., Chow, L. C., Lo, W. Y. V, Song W., & Feldman, G. (2023). Sunk cost effects for time versus money: Replication and extensions Registered Report of Soman (2001), acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/q9s6p
Sunk cost effects for time versus money: Replication and extensions Registered Report of Soman (2001)Nikolay PETROV, Yin Kan (Megan) CHAN, Cheuk Nam (Chris) LAU, Tin Ho (Donald) KWOK, Lok Ching (Estelle) CHOW, Wai Yan (Vivian) LO, Wenkai SONG, Gilad FELDMAN<p>The sunk cost effect is the tendency for an individual's decision-making to be impacted by unrecoverable previous investments of resources. Soman (2001) found that sunk cost effect is weaker for time than for money (Studies 1 and 2) and that th...Social sciencesChris Chambers2023-04-18 20:57:24 View
23 Jan 2023
STAGE 1
toto

Comparing time versus money in sunk cost effects: Replication of Soman (2001)

Are sunk cost effects weaker for time than money?

Recommended by ORCID_LOGO based on reviews by Johanna Peetz, Christopher Olivola, David Ronayne, Johannes Leder and Dilip Soman
The sunk cost fallacy is a cognitive bias in which people persist with a decision that is no longer optimal because of previous resources they have invested (now considered to be spent or “sunk”). Most of us will have heard sunk costs reflected in the saying “throwing good money after bad”, but sunk costs can, in theory, occur more broadly, whether for money, time or any other resource-limited investment. The sunk cost effect for money has been widely studied and appears robust; in contrast, the sunk cost effect for time is more uncertain, and is potentially moderated by the age of respondents (and likely resource availability), the fact that time is irreplaceable, and the tendency for people to account for time less easily than they do for money. In an impactful study, Soman (2001) found that the sunk cost effect for time was indeed weaker than for money, although this finding has not been widely replicated.
 
In the current study, Petrov et al. (2023) propose a replication of three studies from Soman (2001), asking whether sunk costs are weaker for time than for money, and then testing whether the relative absence of a sunk time cost arises from the inability of participants to account for time or due to more rational beliefs in the evaluation of past time investments.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/65htv
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Soman, D. (2001). The mental accounting of sunk time costs: Why time is not like money. Journal of Behavioral Decision Making,14, 169-185. https://doi.org/10.1002/bdm.370
 
2. Petrov, N. B., Chan, Y. K., Lau, C. N., Kwok, T. H., Chow, L. C., Lo, W. Y. V, Song W., & Feldman, G. (2023). Sunk cost effects for time versus money: Replication of Soman (2001) [Registered Report Stage 1], in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/u34zb
Comparing time versus money in sunk cost effects: Replication of Soman (2001) Nikolay Petrov, Wenkai Song, Yin Kan (Megan) CHAN, Cheuk Nam (Chris) LAU, Tin Ho (Donald) KWOK, Lok Ching (Estelle) CHOW, Wai Yan (Vivian) LO, Gilad Feldman (gfeldman@hku.hk)<p>This is a scheduled PCI-RR snap shot for a planned project: "Comparing time versus money in sunk cost effects: Replication of Soman (2001) ​"</p>Social sciencesChris Chambers2022-02-23 10:39:42 View
25 Oct 2023
STAGE 1
toto

Does pupillometry provide a valid measure of spatial attentional bias (pseudoneglect)?

Assessing visuospatial biases (pseudoneglect) using pupillometry: A replication and extension of Strauch et al. (2022)

Recommended by ORCID_LOGO based on reviews by Christoph Strauch and Bianca Hatin
‘Pseudoneglect’ is a small, lateralised bias of visuospatial attention towards the left side of space, and is typically observed in healthy adults. Recently, Strauch et al. (2022) reported that bright stimuli presented in the left visual field induced a greater constriction of the pupil (the pupillary light reflex) compared to the same bright stimuli presented in the right visual field. Further, the pupillary restriction bias was positively correlated with a behavioural measure of pseudoneglect (the greyscales task). This is potentially an important development for attention research, because the passive nature of the task, in addition to the ability to track the time course of the bias measures, could provide a new, and highly sensitive, method of studying spatial attention.
 
In this report, Burns and McIntosh (2023) aim to replicate and extend the study of Strauch et al. (2022). The extension centres around investigating whether the pupillary biases are influenced by recording pupillary responses from the right or left eye. In their pilot replication data, Burns & McIntosh identified a larger constriction in response to stimuli on the right side when recording from the right eye. They hypothesise that pupillary biases may be stronger to stimuli presented in the ipsilateral, rather than contralateral, side of space.
 
The Stage 1 manuscript was reviewed over 2 rounds by 2 reviewers, including the authors of the study being replicated. Based on detailed responses to the reviewers’ comments and edits to the Stage 1 report, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance.
 
URL to the preregistered Stage 1 protocol: https://osf.io/ua9jn

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI-RR-friendly journals:
 
References
 
1. Strauch, C., Romein, C., Naber, M., Van der Stigchel, S. & Ten Brink, A. F. (2022). The orienting response drives pseudoneglect—Evidence from an objective pupillometric method. Cortex, 151, 259-271.
 
2. Burns, N. E. & McIntosh, R. D. (2023). Does pupillometry provide a valid measure of spatial attentional bias (pseudoneglect)? In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/ua9jn
Does pupillometry provide a valid measure of spatial attentional bias (pseudoneglect)?Nicola E. Burns, and Robert D. McIntosh<p>Strauch et al. (2022) introduced a novel approach to assess biases of visual attention, by measuring pupillary constriction in response to split-field stimuli, in which a bright patch is presented to one visual field and a dark patch to the oth...Social sciencesGemma Learmonth Christoph Strauch2023-07-12 18:27:28 View
26 Feb 2024
STAGE 1
toto

Lure of choice revisited: Replication and extensions Registered Report of Bown et al. (2003)

Replicating the "lure of choice" phenomenon

Recommended by ORCID_LOGO based on reviews by Hu Chuan-Peng and Gakuto Chiba
The "lure of choice" refers to the idea that we prefer to preserve the option to choose even when the choice is not helpful. In a classic study cited hundred of times, Bown et al. (2003) reported evidence for the lure of choice from a series of studies involving choices between competing options of night clubs, bank savings accounts, casino spinners, and the Monty Hall door choice paradigm. In all cases, participants tended to prefer to choose an option when paired with a "lure", even when that lure was objectively inferior (e.g., same probability of winning but lower payoff).
 
The lure of choice phenomenon applies to a variety of real-life situations many of us often face in our daily lives, and Bown et al.’s findings have influenced the way organizations present choices to prospective users. Despite their theoretical and practical impact, Bown et al.'s findings have not previously been directly replicated, even as the importance of replication studies has become increasingly acknowledged (Nosek et al., 2022).
 
Here, Chan & Feldman (2024) outline a close replication of Bown et al. (2003) that will replicate and extend their original design. By unifying Bown et al.'s multiple studies into a single paradigm with which they will collect data from approximately 1,000 online participants via Prolific, they will have substantially greater statistical power than the original study to detect the predicted effects. They will follow LeBel et al.’s (2019) criteria for evaluating replicability, such that it will be considered a successful replication depending on how many of the 4 scenarios show a signal in the same direction as Bown et al.’s original results (at least 3 out of 4 scenarios = successful replication; no scenarios = failed replication; 1 or 2 scenarios = mixed results replication). They have also added additional controls including a neutral baseline choice without a lure, further ensuring the the validity and interpretability of their eventual findings.
 
One of the goals in creating Peer Community In Registered Reports (PCI RR) was to increase the availability of publishing venues for replication studies, and so PCI RR is well-suited to the proposed replication. Feldman’s lab has also pioneered the use of PCI RR for direct replications of previous studies (e.g., Zhu & Feldman, 2023), and the current submission uses an open-access template he developed (Feldman, 2023). This experience combined with PCI RR’s efficient scheduled review model meant that the current full Stage 1 protocol was able to go from initial submission, receive detailed peer review by two experts, and receive in-principle acceptance (IPA) for the revised submission, all in less than one month.
 
URL to the preregistered Stage 1 protocol: https://osf.io/8ug9m
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Bown, N. J., Read, D. & Summers, B. (2003). The lure of choice. Journal of Behavioral Decision Making, 16(4), 297–308. https://doi.org/10.1002/bdm.447
 
Chan, A. N. Y. & Feldman, G. (2024). The lure of choice revisited: Replication and extensions Registered Report of Bown et al. (2003) [Stage 1]. In principle acceptance of Version 2 by Peer Community In Registered Reports. https://osf.io/8ug9m
 
Feldman, G. (2023). Registered Report Stage 1 manuscript template. https://doi.org/10.17605/OSF.IO/YQXTP
 
LeBel, E. P., Vanpaemel, W., Cheung, I. & Campbell, L. (2019). A brief guide to evaluate replications. Meta-Psychology, 3. https://doi.org/10.15626/MP.2018.843
 
Nosek, B. A., Hardwicke, T. E., Moshontz, H., Allard, A., Corker, K. S., Dreber, A., ... & Vazire, S. (2022). Replicability, robustness, and reproducibility in psychological science. Annual Review of Psychology, 73(1), 719-748. https://doi.org/10.1146/annurev-psych-020821-114157
 
Zhu, M. & Feldman, G. (2023). Revisiting the links between numeracy and decision making: Replication Registered Report of Peters et al. (2006) with an extension examining confidence. Collabra: Psychology, 9(1). https://doi.org/10.1525/collabra.77608
Lure of choice revisited: Replication and extensions Registered Report of Bown et al. (2003)Nga Yi (Angela) Chan, Gilad Feldman<p>[IMPORTANT: Abstract, method, and results were written using a randomised dataset produced by Qualtrics to simulate what these sections will look like after data collection. These will be updated following the data collection. For the purpose o...Social sciencesPatrick Savage2023-11-15 00:40:47 View
17 Jan 2024
STAGE 1
toto

The Efficacy of Attentional Bias Modification for Anxiety: A Registered Replication

Examining attentional retraining of threat as an intervention in pathological worry

Recommended by ORCID_LOGO based on reviews by Thomas Gladwin, Jakob Fink-Lamotte and 1 anonymous reviewer
Cognitive models ascribe a pivotal role to cognitive biases in the development and maintenance of mental disorders. For instance, attentional biases that prioritize the processing of threat-related stimuli have been suggested to be causally involved in the development and maintenance of anxiety disorders, including generalized anxiety disorder (GAD), which is marked by pathological worry. Therefore, these biases have garnered significant interest as potential diagnostic indicator and as targets for modification.
 
The idea that attention bias modification (ABM) can serve as a therapeutic intervention for GAD and other disorders was fueled by a seminal study by Hazen et al. (2009). In this study, 23 individuals experiencing high levels of worry underwent a computerized attentional retraining of threat stimuli (ARTS) or placebo control training during five training sessions. Relative to control, attention retraining was found to reduce preferential attention to threat, as well as depression and anxiety symptoms. However, as Pond et al. (2024) highlight in their review of the literature, the evidence endorsing the efficacy of ABM in alleviating anxiety disorders is still inconclusive. Moreover, some researchers contend that early positive findings might have been inflated due to demand effects.
 
Based on these considerations, Pond et al. (2024) propose a direct replication of Hazen et al. (2009) by subjecting a high-worry sample to five sessions of ARTS or placebo control. Departing from the frequentist analyses used in the original study, the authors will employ Bayesian analyses that allow more nuanced interpretation of the results, allowing consideration of evidence in support of the null hypothesis. The sampling plan will adhere to a Bayesian stopping rule, whereby the maximal sample size will be set at n=200. Furthermore, the authors extend the original study by addressing potential demand effects. For this purpose, they include a measure of phenomenological control (i.e., the ability to generate experiences align with the expectancies of a given situation) and evaluate its potential moderating impact on the attention bias training.
 
The Stage 1 manuscript was evaluated by three expert reviewers in two rounds of in-depth review. Following responses from the authors, the recommender determined that Stage 1 criteria were met and awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/5f7u9
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Hazen, R. A., Vasey, M. W., & Schmidt, N. B. (2009). Attentional retraining: A randomized clinical trial for pathological worry. Journal of Psychiatric Research, 43, 627-633. https://doi.org/10.1016/j.jpsychires.2008.07.004 
 
2. Pond, N., Meeten, F., Clarke, P., Notebaert, L., & Scott, R. B. (2024). The efficacy of attentional bias modification for anxiety: A registered replication. In principle acceptance of Version 5 by Peer Community in Registered Reports. https://osf.io/5f7u9
 
The Efficacy of Attentional Bias Modification for Anxiety: A Registered ReplicationNathan Pond, Frances Meeten, Patrick Clarke, Lies Notebaert, Ryan Scott<p>Generalised anxiety disorder (GAD) is a prevalent condition that has been linked to the presence of certain cognitive biases, including attention bias. Attention bias is the tendency to attend preferentially to threat-related stimuli and has be...Social sciencesThomas Meyer2023-09-15 19:25:47 View
25 Jun 2023
STAGE 1
toto

Reference points and decision-making: Impact of status quo and defaults in a conceptual replication and extensions Registered Report of Dinner et al. (2011)

Understanding the impact of status quo bias and the default effect on decision-making

Recommended by ORCID_LOGO based on reviews by Laurens van Gestel, Julia Nolte and Sylvain Chabé-Ferret
Everyday decisions can often be biased by how different options are presented and which choices were made previously, over and above whichever option is rationally preferable. Two such major biases in judgment and decision-masking are status quo bias and the default effect. The status quo bias reflects a tendency for people to choose an option that has already been implemented or represents the current state of affairs (for instance, choosing to remain with a current energy supplier rather than switching to a different one, even when the current supplier provides less value for money), while the default effect is a bias toward taking a course of action that would occur automatically in the absence of an active choice (such as the pre-selected energy supplier in questionnaire). Status quo bias and default effects can overlap or diverge: the status quo option will often be the same as the default, while on other occasions the default option in a choice set will be determined by other factors and differ from the option that was already implemented.
 
In the current study, Yam and Feldman (2023) propose a replication and extension of an influential study by Dinner et al. (2011) that purported to examine default effects but, arguably, actually studied its nearby cousin, status quo bias. Using a large online sample, the authors will independently test for the existence of both status quo bias and the default effect, before then asking whether (and if so how) status quo bias and default effects interact and how they are related to several potential explanatory variables, including perceived effort (which may be lower for the status quo or default) and endorsements (whether through direct recommendations or indirectly through perceived norms). The authors also build in additional manipulation checks and comprehension checks, in addition to exploratory analyses examining (among other variables), the political orientation of participants.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/ep3jh
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Dinner, I., Johnson, E. J., Goldstein, D. G., & Liu, K. (2011). Partitioning default effects: Why people choose not to choose. Journal of Experimental Psychology: Applied, 17, 332– 341. https://doi.org/10.1037/a0024354

2. Yam, M. L. M.  & Feldman, G. (2023). Reference points and decision-making: Impact of status quo and defaults in a conceptual replication and extensions Registered Report of Dinner et al. (2011), in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/ep3jh
Reference points and decision-making: Impact of status quo and defaults in a conceptual replication and extensions Registered Report of Dinner et al. (2011)Monique Moon Ling YAM, Gilad Feldman <p>This is a scheduled PCI-RR snap shot for a planned project: "Default, status quo, and past behavior effects: Examining impact of reference points on decisions in a replication and extensions of Dinner et al. (2011)"</p>Social sciencesChris Chambers2023-02-02 06:02:29 View
24 Oct 2022
STAGE 1
toto

Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

Is childhood adversity associated with a heightened response to opioids?

Recommended by ORCID_LOGO based on reviews by Zoltan Dienes, Yuki Yamada and 1 anonymous reviewer
A convergence of evidence suggests that early life adversity may cause dysfunction in opioid-sensitive reward systems. Childhood adversity is associated with opioid use, potentially by altering reward and motivation networks, and experimental models in animals have found that early life adversity increases and consolidates opioid seeking behaviours. Further, in a recent controlled experiment, Carlyle et al. (2021) found that opioid administration produced stronger positive responses, and weaker negative responses, in adults with a history of childhood abuse and neglect.
 
In the current study, Carlyle et al. seek to test the generalisability of these previous findings in a pre-operative clinical setting. Using partially observed data from an existing cohort study (N=155), the authors will test whether patients with greater experience of childhood trauma in turn exhibit a larger mood boost and express greater subjective pleasure following opioid administration. Although not a randomised experimental design, this study provides the opportunity to examine the relationship between opioid response and history of childhood adversity in a naturalistic setting, and thus has the potential to either support or cast doubt on the theory that adversity elevates risk of opioid addiction by altering sensitivity to subjectively pleasurable effects.
 
Following three rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/7ymts
 
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question AND they have taken additional steps to maximise bias control and rigour. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Carlyle M., Broomby R., Simpson G., Hannon R., Fawaz L., Mollaahmetoglu O.M., Drain, J., Mostazir, M., & Morgan C. (2021). A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine. Addiction Biology, 26(6):e13047.
 
2. Carlyle, M., Kvande, M., Leknes, S., Meier, I., Buen, K., Jensen, E. N., Ernst, G. & Eikemo, M. (2022). Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery, in principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/7ymts
Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgeryMolly Carlyle*, Malin Kvande*, Siri Leknes, Isabell Meier, Kaja Buen, Eira Nordeng Jensen, Gernot Ernst, Marie Eikemo. *denotes equal contribution. <p>PCI-RR Snapshot only</p>Life Sciences, Medical Sciences, Social sciencesChris Chambers2022-03-15 10:07:29 View
11 Apr 2023
STAGE 2
(Go to stage 1)
toto

Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery

Is childhood adversity associated with a heightened response to opioids?

Recommended by ORCID_LOGO based on reviews by Zoltan Dienes, Yuki Yamada and 1 anonymous reviewer
A convergence of evidence suggests that early life adversity may cause dysfunction in opioid-sensitive reward systems. Childhood adversity is associated with opioid use, potentially by altering reward and motivation networks, and experimental models in animals have found that early life adversity increases and consolidates opioid seeking behaviours. Further, in a recent controlled experiment, Carlyle et al. (2021) found that opioid administration produced stronger positive responses, and weaker negative responses, in adults with a history of childhood abuse and neglect.
 
In the current study, Carlyle et al. (2023) tested the generalisability of these previous findings in a pre-operative clinical setting. Using partially observed data from an existing cohort study (N=155), the authors asked whether patients with greater experience of childhood trauma in turn exhibit a larger mood boost and express greater subjective pleasure following opioid administration.
 
In contrast to previous findings, the results did not support the hypotheses that more experiences of childhood adversity would heighten ratings of drug liking and feeling good following opioid administration. Regression analyses instead revealed a statistically significant negative association between childhood adversity and post-opioid liking and no significant relationship with feeling good. The authors suggest that the discrepancy between the current and previous results may be due to stress related to the pre-surgical setting, the brief duration of drug exposure, and the relatively limited levels of high childhood adversity in the study sample. Nevertheless, these findings cast some doubt on the theory that adversity elevates risk of opioid addiction by altering sensitivity to subjectively pleasurable effects.
 
Following one round of in-depth review, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/7ymts
 
Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors prior to IPA, but the authors certify that they had not yet observed the key variables within the data that were used to answer the research question AND they took additional steps to maximise bias control and rigour. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Carlyle M., Broomby R., Simpson G., Hannon R., Fawaz L., Mollaahmetoglu O.M., Drain, J., Mostazir, M., & Morgan C. (2021). A randomised, double‐blind study investigating the relationship between early childhood trauma and the rewarding effects of morphine. Addiction Biology, 26(6):e13047. https://doi.org/10.1111/adb.13047
 
2. Carlyle, M., Kvande, M., Meier, I. M., Trøstheim, M., Buen, K., Jensen, E. N., Ernst, G. & Leknes, S. & Eikemo, M. (2023). Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgery, acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/9kt3a?view_only=4238d2ee3d654c4f908a94efea82a027
Does childhood adversity alter opioid drug reward? A conceptual replication in outpatients before surgeryMolly Carlyle1*, Malin Kvande*, Isabell M. Meier, Martin Trøstheim, Kaja Buen, Eira Nordeng Jensen, Gernot Ernst, Siri Leknes, Marie Eikemo (*denotes equal contribution)<p><strong>Introduction</strong>: Opioid analgesic treatment during surgery entails risk of persistent use. Experiences of childhood adversity have been shown to increase opioid reward in preclinical models, a finding recently extended to healthy ...Medical Sciences, Social sciencesChris Chambers2023-02-02 08:29:18 View