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IdTitleAuthorsAbstractPictureThematic fieldsRecommender▼ReviewersSubmission date
03 Jul 2023
STAGE 2
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Globally, songs and instrumental melodies are slower, higher, and use more stable pitches than speech [Stage 2 Registered Report]

Strong evidence for cross-cultural regularities in music and speech

Recommended by ORCID_LOGO based on reviews by Bob Slevc and Nai Ding
For centuries, the ubiquity of language and music across human societies has prompted scholars to speculate about their cross-cultural origins as well as their shared and unique characteristics. Depending on the extent to which contemporary theories emphasise the role of biology vs. culture, a range of hypotheses have been proposed concerning expected similarities and differences in song and speech. One class of hypotheses stemming from cultural relativism assumes a lack of universal regularities in song and speech, and therefore predicts no systematic cross-cultural relationships. On the other hand, more recent evolutionary hypotheses such as the social bonding hypothesis, motor constraint hypothesis, and sexual selection hypothesis all predict differences or similarities in specific characteristic of vocalisations, such as pitch regularity, pitch interval size, and melodic contour. Existing results are mixed in their support of these predictions.
 
In the current study, Ozaki et al. (2023) elucidated cross-cultural similarities and differences between speech and song in 75 different linguistic varieties spanning 21 language families. Understanding precisely how song and speech are related is methodologically challenging due to the multitude of confounds that can arise in comparing natural recordings. Here the authors overcame these difficulties with four types of carefully controlled recordings: singing, recitation of sung lyrics, spoken description of the song, and instrumental version of the sung melody. The authors then examined six features that are amenable to reliable comparison, including pitch height, temporal rate, pitch stability, timbral brightness, pitch interval size, and pitch declination. With this data in hand, the authors asked which acoustic features differ reliably between song and speech across cultures, with the expectation that song would exhibit higher pitch, slower rate and more stable pitch than speech. At the same time, the authors expected song and speech to be reliably similar in the characteristics of timbral brightness, pitch intervals and pitch contours
 
The findings provided strong support for the preregistered hypotheses. Relative to speech, songs exhibited higher pitch, slower temporal rate, and more stable pitches, while both songs and speech had similar pitch interval size and timbral brightness. Only one hypothesis was unsupported, with the comparison of pitch declination between song and speech turning out inconclusive. To overcome potential sources of analytic bias, the authors undertook additional robustness checks, including reanalysis of a previously published dataset of over 400 song/speech recordings; this exploratory analysis corroborated the conclusions from the confirmatory analysis. Overall this study offers a unique insight into the shared global characteristics of langage and music, with implications for understanding their cultural and biological (co)evolution.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and therefore awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/jdhtz
 
Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors, but the authors certify that they had not yet observed the key variables within the data that were be used to answer the research question AND they took additional steps to maximise bias control and rigour.

List of eligible PCI RR-friendly journals:
 
 
References
 
1. Ozaki, Y. et al. (2023). Globally, songs and instrumental melodies are slower, higher, and use more stable pitches than speech [Stage 2 Registered Report]. Acceptance of Version 11 by Peer Community in Registered Reports. https://doi.org/10.31234/osf.io/jr9x7
Globally, songs and instrumental melodies are slower, higher, and use more stable pitches than speech [Stage 2 Registered Report]Yuto Ozaki, Adam Tierney, Peter Pfordresher, John Mcbride, Emmanouil Benetos, Polina Proutskova, Gakuto Chiba, Fang Liu, Nori Jacoby, Suzanne Purdy, Patricia Opondo, Tecumseh Fitch, Shantala Hegde, Martín Rocamora, Rob Thorne, Florence Ewomazino N...<p>What, if any, similarities and differences between music and speech are consistent across cultures? Both music and language are found in all known human societies and are argued to share evolutionary roots and cognitive resources, yet no studie...Humanities, Social sciencesChris Chambers2023-05-16 17:22:17 View
08 Nov 2023
STAGE 2
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Relationship between creativity and depression: the role of reappraisal and rumination

Evidence for a weak relationship between creativity and depressive traits

Recommended by ORCID_LOGO
For centuries, the relationship between creativity and mental health has been a subject of fascination, propelled by the impression that many of the most famous artists in history likely suffered from mood disorders or other mental illnesses. However, with the advent of psychological science – including more precise and diagnostic clinical measures – the empirical evidence for an association between creativity and depressive symptoms has been mixed, with some studies suggesting a positive relationship and others showing either no effect or indicating that the link, if there is one, may be driven by other personality characteristics (Verhaeghen et al., 2005).
 
In the current study, Lam and Saunders used an online design in 201 participants to ask whether creativity is associated with higher depressive traits, and further, whether that relationship depends on two additional variables that could explain an observed positive correlation: self-reflective rumination (repetitive thoughts that maintain a negative mood state) and the frequency with which individuals engage in reappraisal (a regulation strategy that involves reinterpreting an event or situation to diminish its negative impact).
 
Results showed mixed support for the hypotheses. Contrary to expectations, the relationship between creativity and depression was significantly negative rather than positive. However, even though the directionality of this relationship was opposite to predicted, the hypothesis that the association between creativity and depression is mediated by self-reflective rumination was supported. Finally, the results disconfirmed the hypothesis that reappraisal frequency contributes to the relationship between creativity and depression. Exploratory analyses indicated no reliable moderating role of gender. Overall, these findings suggest that creativity and depression may be only weakly related, and that self-reflective rumination could account for that relationship.
 
The Stage 2 manuscript was evaluated over one round of review provided by the recommender and Managing Board, as the Stage 1 reviewers were no longer available. Based on additional changes to the manuscript, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/yub7n
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Verhaeghen, P., Joormann, J., & Khan, R. (2005). Why we sing the blues: The relation between self-reflective rumination, mood, and creativity. Emotion, 5, 226-232. https://doi.org/10.1037/1528-3542.5.2.226
 
2. Lam, C. Y. & Saunders, J. A. (2023). Relationship between creativity and depression: the role of reappraisal and rumination [Stage 2 Registered Report]. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/z3ap5
Relationship between creativity and depression: the role of reappraisal and ruminationChin Yui Lam and Jeffrey Allen Saunders<p>Previous research has found mixed evidence about whether increased creativity is associated with higher depression. We investigated the relationship between creativity and depression, and the role of two emotion regulation strategies: ruminatio...Social sciencesChris Chambers2023-07-27 11:42:43 View
08 Nov 2023
STAGE 2
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Responding to Online Toxicity: Which Strategies Make Others Feel Freer to Contribute, Believe That Toxicity Will Decrease, and Believe that Justice Has Been Restored?

Benevolent correction may provide a promising antidote to online toxicity

Recommended by ORCID_LOGO based on reviews by Corina Logan and Marcel Martončik
Social media is a popular tool for online discussion and debate, bringing with it various forms of hostile interactions –  from offensive remarks and insults, to harassment and threats of physical violence. The nature of such online toxicity has been well studied, but much remains to be understood regarding strategies to reduce it. Existing theory and evidence suggests that a range of responses – including those that emphasise prosociality and empathy – might be effective at mitigating online toxicity. But do such strategies work in practice?
 
In the current study, Young Reusser et al (2023) tested the effectiveness of three types of responses to online toxicity – benevolent correction (including disagreement), benevolent going along (including joking/agreement) and retaliation (additional toxicity) – on how able participants feel to contribute to conversations, their belief that the toxicity would be reduced by the intervention, and their belief that justice had been restored.
 
The results showed the benevolent correction – while an uncommon strategy in online communities – was most effective in helping participants feel freer to contribute to online discussions. Benevolent correction was also the preferred approach for discouraging toxicity and restoring justice. Overall, the findings suggest that responding to toxic commenters with empathy and understanding while (crucially) also correcting their toxicity may be an effective intervention for bystanders seeking to improve the health of online interaction. The authors note that future research should focus on whether benevolent correction actually discourages toxicity, which wasn't tested in the current experiment, and if so how the use of benevolent corrections might be encouraged.
 
Following one round of review and revisions, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/hfjnb
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Young Reusser, A. I., Veit, K. M., Gassin, E. A., & Case, J. P. (2023). Responding to Online Toxicity: 
Which Strategies Make Others Feel Freer to Contribute, Believe That Toxicity Will Decrease, and Believe that Justice Has Been Restored? [Stage 2 Registered Report] Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/k46e8
Responding to Online Toxicity: Which Strategies Make Others Feel Freer to Contribute, Believe That Toxicity Will Decrease, and Believe that Justice Has Been Restored?Alison I. Young Reusser, Kristian M. Veit, Elizabeth A. Gassin, and Jonathan P. Case<p>When we encounter toxic comments online, how might individual efforts to reply to those comments improve others’ experiences conversing in that forum? Is it more helpful for others to publicly, but benevolently (with a polite tone, demonstrated...Social sciencesChris Chambers2023-08-02 05:30:37 View
08 Dec 2023
STAGE 1
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An #EEGManyLabs study to test the role of the alpha phase on visual perception (a replication and new evidence)

Understanding the relationship between alpha oscillations and visual perception

Recommended by ORCID_LOGO based on reviews by Chris Allen, Luca Ronconi and Alexander Jones
For nearly a century, rhythmic patterns in electrical brain activity have been of major interest in neuroscience and electrophysiology, but much remains to be discovered about their causal contribution to cognition and behaviour. Low-frequency oscillations in the alpha band (~8-13 Hz) have been suggested to facilitate the organisation and delivery of visual information to higher-level systems, including those involved in perception and decision-making. If so, visual perception should also operate in cycles that are synchronous with – and determined by – the phase of ongoing low-frequency oscillatory activity.
 
In this #EEGManyLabs study, Ruzzoli et al. (2023) propose a large-scale, multi-lab investigation (9 labs; N=315 human participants) of the relationship between the phase of alpha oscillations and visual perception. The authors focus in particular on replicating a formative study by Mathewson et al. (2009) which reported that during high-amplitude alpha fluctuations, stimulus visibility depended on the time the stimulus was presented relative to the phase of the pre-stimulus alpha activity. In addition, the amplitude of visual evoked potentials recorded with EEG was larger when the target was presented at peaks in pre-stimulus alpha. To explain their findings, Mathewson proposed an influential pulsed inhibition hypothesis in which low alpha power boosts both cortical excitability and stimulus processing (and hence perception), while high alpha power makes stimulus processing dependent on the phase during the alpha cycle at which the stimulus is presented.
 
In the first of (up to) two studies, the authors will seek to directly replicate the key finding of Mathewson et al: that when alpha power is high, the oscillatory phase determines perceptual performance and event-related electrophysiological correlates in a masked visual detection task. Specifically, (a) alpha oscillations are predicted to modulate the probability of perceiving a target stimulus within a single oscillatory cycle, with detection rate associated with separated (and potentially opposite) phase angles, and (b) alpha phase at the onset of the stimulus should drive electrophysiological correlates of stimulus processing (including the amplitude and/or latency of the N1 ERP component).
 
Provided the results of this first study do not conclusively disconfirm these hypotheses, the authors will then conduct a follow-up study in which the temporal predictability of the target onset (in relation to a fixation stimulus) is reduced to test the more severe hypothesis that the observed correlations between alpha phase and perception are linked directly to ongoing oscillations, independent of temporal expectations.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/scqj8​ (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Ruzzoli, M., Cuello, M. T., Molinaro, N., Benwell, C. S. Y., Berkowitz, D., Brignani, D., Falciati, L., Harris, A. M., Keitel, C., Kopčanová, M., Madan, C. R., Mathewson, K., Mishra, S., Morucci, P., Myers, N., Nannetti, F., Nara, S., Pérez-Navarro, J., Ro, T., Schaworonkow, N., Snyder, J. S., Soto-Faraco, S., Srinivasan, N., Trübutschek, D., Zazio, A., Mushtaq, F., Pavlov, Y. G., & Veniero, D. (2023). In principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/scqj8​
 
2. Mathewson, K. E., Gratton, G., Fabiani, M., Beck, D. M., & Ro, T. (2009). To see or not to see: prestimulus α phase predicts visual awareness. Journal of Neuroscience, 29, 2725-2732. https://doi.org/10.1523/JNEUROSCI.3963-08.2009
An #EEGManyLabs study to test the role of the alpha phase on visual perception (a replication and new evidence)Manuela Ruzzoli, Mireia Torralba Cuello, Nicola Molinaro, Christopher S.Y. Benwell, Daniel Berkowitz, Debora Brignani, Luca Falciati, Anthony M. Harris, Christian Keitel, Martina Kopčanová, Christopher R. Madan, Kyle Mathewson, Sudhakar Mishra, Pi...<p>Several studies have suggested that low-frequency brain oscillations could be key to understanding how the brain samples sensory information via rhythmic alternation of low and high excitability periods. However, this hypothesis has recently be...Humanities, Social sciencesChris Chambers2023-08-03 12:59:33 View
27 Feb 2024
STAGE 2
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Revisiting the motivated denial of mind to animals used for food: Replication Registered Report of Bastian et al. (2012)

Confirmatory evidence that the denial of animal minds explains the "meat paradox"

Recommended by ORCID_LOGO based on reviews by Brock Bastian, Ben De Groeve and Florian Lange
The psychology of meat-eating offers a fascinating window into moral reasoning, cognition and emotion, as well as applications in the shift toward more sustainable and ethical alternatives to meat consumption. One key observation in this field is the so-called “meat paradox” – the tendency for people to simultaneously eat meat while also caring about animals. One way to resolve this conflict and reduce cognitive dissonance is for people to separate the concept of meat from animals, mentally disengaging from the origins of meat in order to make the act of consumption more ethically acceptable. Another potential explanation is a motivated “denial of mind”, in which people believe that animals lack the mental capacity to experience suffering; therefore, eating an animal is not a harm that the animal will experience. In support of the latter hypothesis, Bastian et al (2012) found that animals judged to have greater mental capacities were also judged as less edible, and that simply reminding meat eaters that an animal was being raised for the purposes of meat consumption led to denial of its mental capacities.
 
Using a large-scale online design in 1000 participants, Jacobs et al. (2024) replicated two studies from Bastian et al. (2012): asking how the perceived mental capabilities of animals relates to both their perceived edibility and the degree of moral concern they elicit, and whether learning that an animal will be consumed influences perceptions of its mental capabilities. The original findings were successfully replicated. For study 1, attributions of mind were negatively related to animals’ edibility, positively related to negative affect towards eating animals, and positively related to moral concern for animals. For study 2, learning that an animal would be used for food led participants to attribute less mind to the animal. Overall, the results strengthen the conclusion that motivated denial of animal minds can be a mechanism for resolving the ‘meat paradox’.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/cru4z
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Bastian, B., Loughnan, S., Haslam, N., & Radke, H. R. M. (2012). Don’t mind meat? The denial of mind to animals used for human consumption. Personality and Social Psychology Bulletin, 38, 247–256. https://doi.org/10.1177/0146167211424291
 
2. Jacobs, T. P., Wang, M., Leach, S., Loong, S. H., Khanna, M., Chan, K. W., Chau, H. T., Tam, Y. Y. & Feldman, G. (2024). Revisiting the motivated denial of mind to animals used for food: Replication and extension of Bastian et al. (2012) [Stage 2]. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/mwyde
Revisiting the motivated denial of mind to animals used for food: Replication Registered Report of Bastian et al. (2012)Tyler P. Jacobs, Meiying Wang, Stefan Leach, Ho Loong Siu, Mahika Khanna, Ka Wan Chan, Ho Ting Chau, Yuen Yan Tam, Gilad Feldman<p>Bastian et al. (2012) argued that the ‘meat paradox’–caring for animals yet eating them–exemplifies the motivated moral disengagement driven by a psychologically aversive tension between people’s moral standards (caring for animals) and their b...Social sciencesChris Chambers2023-08-10 21:19:16 View
04 Dec 2023
STAGE 2
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The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered Report

Brooding increases conspiracy beliefs but with practical significance to be determined

Recommended by ORCID_LOGO based on reviews by Matt Williams and Daniel Toribio-Flórez
The world is seemingly awash with conspiracy theories – from well-trodden examples such as fake Moon landings, the 9/11 truth movement, and Holocaust denial, to relative newcomers including COVID as a bioweapon, QAnon, and the belief that the science of climate change has been invented or falsified. While there is a public perception that conspiracy theories are becoming more prevalent, recent evidence suggests that the rate of conspiracism is relatively stable over time (Uscinski et al., 2022). At any point in history, it seems that a certain proportion of people find themselves vulnerable to conspiracy beliefs, but what distinguishes those who do from those who don’t, and what are the causal factors?
 
In the current study, Liekefett et al. (2023) investigated the critical role of rumination – a perseverative and repetitive focus on negative content leading to emotional distress. In particular, the authors asked whether one component of rumination referred to as brooding (dwelling on one’s worries and distressing emotions) has a specific causal role in the formation of conspiracy beliefs. In a series of preliminary experiments, the authors first established a procedure for successfully inducing rumination, identifying various boundary conditions and requirements for a successful design. In the main study (N=1,638 to 2,007 depending on the analysis), they asked whether the induction of brooding causes a significant increase in conspiracy beliefs. Manipulation checks were also included to confirm intervention fidelity (independently of this hypothesis), and exploratory analyses tested the effect of various moderators, as well as the causal role of a complementary manipulation of reflection – a component of rumination in which attention is focused on the issue at hand rather than one’s emotions.
 
As expected by the authors' preliminary work, manipulation checks independently confirmed the effectiveness of the brooding intervention. In answer to the main research question, participants who brooded over the worries and negative emotions associated with an issue were more susceptible to conspiracy beliefs compared to a control group. However, while this effect of brooding was statistically significant, the confidence interval of the effect size estimate overlapped with the authors' proposed smallest effect size of interest (d = 0.20), suggesting that the practical value of the effect remains to be determined.
 
Overall the findings are consistent with a range of psychological theories suggesting that rumination induces negative affect and/or narrows attention to negative information, which in turn may make conspiracy theories seem more probable and render individuals more vulnerable to cognitive bias. The authors note the importance of future work to define the smallest effect of practical significance, analagous to the criteria used to determine the 'minimal clinically important difference’ in medical research.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/y82bs
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Uscinski, J., Enders, A., Klofstad, C., Seelig, M., Drochon, H., Premaratne, K. & Murthi, M. (2022) Have beliefs in conspiracy theories increased over time? PLOS ONE 17: e0270429. https://doi.org/10.1371/journal.pone.0270429

2. Liekefett, L. Sebben, S. & Becker, J. C. (2023). The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered Report. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/3e8wc
The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered ReportLuisa Liekefett, Simone Sebben, Julia C. Becker<p>This Stage 2 Registered Report concerns the relationship between rumination, a repetitive style of negative thinking, and conspiracy beliefs (Stage 1 protocol: https://osf.io/y82bs, date of in-principle-acceptance: 23/05/2023). Based on four pi...Humanities, Social sciencesChris Chambers2023-10-19 17:46:59 View
23 Nov 2023
STAGE 2
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The Medusa effect: A registered replication report of Will, Merritt, Jenkins, and Kingstone (2021)

Looking (again) at Medusa: Evidence that pictorial abstraction influences mind perception

Recommended by ORCID_LOGO based on reviews by Alan Kingstone and 1 anonymous reviewer
The Medusa effect is a recently described phenomenon in which people judge a person to be more mindful when they appear as a picture (termed L1) than as a picture within a picture (L2). Across a series of experiments, Will et al. (2021) reported that at higher levels of abstraction, images of people were judged lower in realness (how real the person seemed), experience (the ability to feel) and agency (the ability to plan and act), and also benefited less from prosocial behaviour. The findings provide an intriguing window into mind perception – the extent to which we attribute minds and mental capacities to others.
 
In the current study, Han et al. (2023) undertook a close replication of two experiments from the original report by Will et al. (2021), asking first, whether the level of pictorial abstraction influences ratings of realness, agency and experience, and second, whether it also influences prosocial behaviour as measured in the dictator game (with participants predicted to allocate more money to recipients presented as pictures than as pictures within pictures). In the event of a non-replication using the original materials, the authors planned to further repeat the experiments using newly generated stimuli that are better matched for cultural context and more tightly controlled along various dimensions.
 
Results supported all pre-registered hypotheses. Participants rated and perceived L1 stimuli as having significantly higher levels of realness, agency, and experience than L2, and they also allocated significantly more money to L1 recipients than L2 recipients in a dictator game. Furthermore, participants who judged L1 as higher than L2 on all three dimensions also differentiated significantly between L1 and L2 in the dictator game, indicating a relationship between mind perception and prosociality. Overall, the findings confirm that pictures with lower levels of abstraction are perceived as more mindful and are associated with higher levels of prosocial behavior. Consequently, the results suggest that the Medusa effect is a reproducible phenomenon.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/xj46z
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Will, P., Merritt, E., Jenkins, R., & Kingstone, A. (2021). The Medusa effect reveals levels of mind perception in pictures. Proceedings of the National Academy of Sciences, 118(32), e2106640118. https://doi.org/10.1073/pnas.2106640118
 
2. Han, J., Zhang, M., Liu, J., Song, Y. & Yamada, Y. (2023).The Medusa effect: A registered replication report of Will, Merritt, Jenkins, and Kingstone (2021). Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/yqnu8
The Medusa effect: A registered replication report of Will, Merritt, Jenkins, and Kingstone (2021)Jing Han, Minjun Zhang, Jiaxin Liu, Yu Song, Yuki Yamada<p>Will et al.'s (2021) found the Medusa effect, which refers to the tendency that people evaluate a “person in picture” more mindful than a “person in picture of a picture”. The present study tried to directly replicate the Experiments 2 and 5 of...Social sciencesChris Chambers2023-10-24 03:42:14 View
28 Feb 2024
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Genetically-modified animals as models of neurodevelopmental conditions: a review of systematic review reporting quality

Evidence for mixed quality of systematic reviews in preclinical animal studies of neurodevelopmental conditions

Recommended by ORCID_LOGO based on reviews by Marietta Papadatou-Pastou
Single gene alterations have been estimated to account for nearly half of neurodevelopmental conditions (NDCs), providing a crucial opportunity for animal models to understand the underlying mechanisms, causes and potential treatments. The use of systematic reviews (SRs) can, in principle, provide a powerful means to synthesise this evidence-base; however, the reporting quality of previous SRs in preclinical animal research has been found lacking (Hunniford et al., 2021). In the current study, Wilson et al. (2023) will undertook a review of systematic reviews to assess the characteristics and reporting quality of SRs that, in turn, synthesise research in genetically-modified animals to model NDCs. In particular, the authors extracted key features of reviews (including, among others, the aim and primary research questions, relevant animal model, and number of studies in the SR), in addition to quality indicators such as risk of bias and completeness of reporting. In doing so, the authors aimed to enhance guidance on the conduct and reporting of systematic reviews in this area.
 
Of twelve publications that met the preregistered search criteria, the completeness and quality of reporting was variable. Among the better reported characteristics were search strategies (9 of 12 articles), reporting of funding sources (10 of 12 articles) and use of animal data (11 of 12 articles). In contrast, only two articles reported whether the study protocol was preregistered, only three articles reported methods for assessing risk of bias, and just one included methods to analyse publication bias. In addition, the authors identified 19 review registrations via PROSPERO, most of which remained unpublished after their anticipated end dates. Overall, the results highlight the importance of adherence to reporting guidelines for increasing the transparency and reproducibility of SRs in this field.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses by the authors, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/952qk
 
Level of bias control achieved: Level 4. At least some of the data/evidence that was used to answer the research question already existed prior to IPA and was accessible in principle to the authors, but the authors certify that they did not access any part of that data/evidence prior to IPA.
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Hunniford V. T., Montroy J., Fergusson D. A., Avey M. T., Wever K. E., McCann S. K., Foster M., Fox G., Lafreniere M., Ghaly M., Mannell S., Godwinska K., Gentles A., Selim S., MacNeil J., Sikora L., Sena E. S., Page M. J., Macleod M., Moher D., & Lalu M. M. (2021). Epidemiology and reporting characteristics of preclinical systematic reviews. PLOS Biology, 19:e3001177. https://doi.org/10.1371/journal.pbio.3001177
 
2. Wilson, E., Currie, G., Macleod, M., Kind, P. & Sena, E. S. (2023). Genetically-modified animals as models of neurodevelopmental conditions: a review of systematic review reporting quality [Stage 2]. Acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/s5xd4
Genetically-modified animals as models of neurodevelopmental conditions: a review of systematic review reporting qualityEmma Wilson, Gillian Currie, Malcolm Macleod, Peter Kind, and Emily S Sena<p><strong>Objective</strong><br>Using genetically-modified animals to model neurodevelopmental conditions (NDCs) helps better our understanding of biology underlying these conditions. Animal research has unique characteristics not shared with cli...Medical SciencesChris Chambers2023-11-22 10:26:44 View
30 Apr 2024
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A climate action intervention to boost individual and collective climate mitigation behaviors in young adults

Putting climate action intervention to the test: Part 1

Recommended by ORCID_LOGO based on reviews by Helen Landmann, Jana Kesenheimer and 1 anonymous reviewer
It is increasingly recognised that resolving the climate crisis will require not only the reform of law and government policy but collective grassroots action to change individual behaviour and put public pressure on political leaders, companies and institutions to cut emissions. The capacity, however, for individual citizens to take such steps is limited by lack of knowledge/awareness of means and opportunities as well as psychological barriers that can make such actions seem impossible, fruitless or against the person's immediate self-interest. Interventions designed to overcome these obstacles and promote individual behaviour change have met with only limited success, with many based on weak psychological evidence and the outcome measures used to evaluate their success prone to error and bias.
 
In the current submission, Castiglione et al. (2024) propose a series of five studies to test, evaluate, and optimise a longitudinal intervention for engaging young adults (aged 18-35) in individual and collective climate action. Building on existing theory and evidence, the authors have designed an intensive 6-week educational intervention that draws on 12 psychological factors linked to pro-environmental behaviour, including emotional engagement, self-efficacy, collective efficacy, theory of change, cognitive alternatives, perceived behavioral control, implementation intentions, social norms, self-identity, collective identity, appraisal, and faith in institutions. Through the use of ecological momentary assessment (EMA), they plan to measure these targeted psychological correlates as well as individual and collective climate engagement of participants before and after the intervention (and in active groups vs. controls), and then again after a further three months.
 
The current submission is novel in being the first at PCI RR (and possibly the first RR anywhere) to propose an incremental programmatic workflow that combines two innovations: a single Stage 1 protocol leading to multiple Stage 2 outputs (under the PCI RR programmatic track) and a prespecification in which the design of the intervention in later studies is (for now) determined only broadly, with specific parameters to be shaped by the results of the first set of studies (under the PCI RR incremental registrations policy). This particular Stage 1 manuscript specifies the design of study 1 in two samples (high-school and university students in Italy; producing one Stage 2 output for each sample) and the general design of subsequent studies. The details of this later research in study 2 (in the same two populations) and study 3 (university students in the Netherlands) will be developed sequentially based on the results of the previous Stage 2 outputs and the state of the literature at that time.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA). Following the completion of study 1, the authors will submit an updated Stage 1 manuscript for re-evaluation that updates the plans for later studies accordingly, hence the current recommendation is labelled "Part 1".
 
URL to the preregistered Stage 1 protocol: https://osf.io/zh3w9 (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Castiglione, A., Brick, C., Esposito, G., & Bizzego, A. (2024). A climate action intervention to boost individual and collective climate mitigation behaviors in young adults. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/zh3w9
A climate action intervention to boost individual and collective climate mitigation behaviors in young adultsAnna Castiglione, Cameron Brick, Gianluca Esposito, Andrea Bizzego<p>We present a programmatic research line to test whether a longitudinal intervention aiming to increase key psychological correlates of pro-environmental behavior motivates young adults to take climate action. In five longitudinal studies, we wi...Social sciencesChris Chambers Tyler Jacobs, Matt Williams2024-01-11 16:25:49 View
22 Apr 2024
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Progression of white matter hyperintensities is related to blood pressure increases and global cognitive decline – a registered report

White matter lessions are associated with increases in blood pressure and global cognitive decline

Recommended by ORCID_LOGO based on reviews by Isabel Garcia Garcia
Cerebral small vessel disease (CSVD) is a common and multi-faceted set of pathologies that affect the small arteries, arterioles, venules and capillaries of the brain. The disease manifests through a range of symptoms and conditions, including psychiatric disorders, abnormal gait, and urinary incontinence, while accounting for 25% of strokes and nearly 50% of dementia.
 
The presence of CSVD is associated with white matter lesions detected as white matter hyperintensities (WMH) using neuroimaging, which have in turn been shown to predict future stroke, cognitive decline and dementia. While vascular risk factors of CSVD (such as hypertension and obesity) are also associated with CSVD, a complete picture of the predictive relationship between WMH, cognitive decline, and blood pressure remains to be determined, as does the role of sex/gender. These inter-relationships are important to determine for improving the diagnosis and treatment of CSVD.
 
In the current study, Beyer et al. analysed a large emerging dataset from the LIFE-Adult project – a longitudinal, two-wave, population-based study – to ask whether higher blood pressure predicts a greater increase in WMH, and whether progression of WMH is associated with measures of memory and executive function. In addition, the authors explored the relationship between abdominal obesity and WMH progression, and the extent to which WMH progression, and its interaction with vascular risk factors, depends on sex/gender.
 
Results revealed no reliable association between baseline blood pressure with WMH progression. WMH progression significantly predicted global cognitive decline but not decline in executive function specifically. Exploratory analyses revealed that increases in diastolic blood pressure as well as baseline and systolic blood pressure were associated with WMH progression, specifically in frontal periventricular regions, but there was no association of waist-to-hip ratio (a proxy of abdominal fat deposits) with WMH progression nor any gender-specific associations. The authors conclude that strict control of blood pressure might confer a protective effect, limiting WMH progression and negative effects on global cognitive function in the middle-aged to older population.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on responses to the reviewer's comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/qkbgj
 
Level of bias control achieved: Level 2. At least some data/evidence that was used to answer the research question had been accessed and partially observed by the authors prior to Stage 1 in-principle acceptance, but the authors certify that they had not yet observed the key variables within the data that were used to answer the research question.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Beyer, F., Lammer, L., Loeffler, M., Riedel-Heller, S., Debette, S., Villringer, A. & Witte, A. V. (2023). Progression of white matter hyperintensities is related to blood pressure increases and global cognitive decline – a registered report [Stage 2]. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/k24pm
Progression of white matter hyperintensities is related to blood pressure increases and global cognitive decline – a registered reportFrauke Beyer, Laurenz Lammer, Markus Loeffler, Steffi Riedel-Heller, Stéphanie Debette, Arno Villringer, A. Veronica Witte<p>Introduction<br>White matter hyperintensities (WMH) reflect cerebral small vessel disease (cSVD), a major brain pathology contributing to cognitive decline and dementia. Vascular risk factors including higher diastolic blood pressure (DBP) have...Humanities, Medical SciencesChris Chambers2024-02-15 17:16:37 View