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IdTitle * Authors * Abstract * PictureThematic fields * RecommenderReviewersSubmission date
23 May 2023
STAGE 1

Does Brooding Meaningfully Increase the Likelihood of Believing in a Conspiracy? A Registered Report

Does brooding increase conspiracy beliefs?

Recommended by ORCID_LOGO based on reviews by Matt Williams and 1 anonymous reviewer
The world is seemingly awash with conspiracy theories – from well-trodden examples such as fake Moon landings, the 9/11 truth movement, and Holocaust denial, to relative newcomers including COVID as a bioweapon, QAnon, and the belief that the science of climate change has been invented or falsified. While there is a public perception that conspiracy theories are becoming more prevalent, recent evidence suggests that the rate of conspiracism is relatively stable over time (Uscinski et al., 2022). At any point in history, it seems that a certain proportion of people find themselves vulnerable to conspiracy beliefs, but what distinguishes those who do from those who don’t, and what are the causal factors?
 
In the current study, Liekefett et al. (2023) investigate the critical role of rumination – a perseverative and repetitive focus on negative content leading to emotional distress. In particular, the authors ask whether one component of rumination referred to as brooding (dwelling on one’s worries and distressing emotions) has a specific causal role in the formation of conspiracy beliefs. In a series of preliminary experiments, the authors first established a procedure for successfully inducing rumination, identifying various boundary conditions and requirements for a successful design. In the proposed study (of up to N=1,638), they will then ask whether the induction of brooding causes a significant increase in conspiracy beliefs. Manipulation checks will be included to confirm intervention fidelity (independently of this hypothesis), and exploratory analyses will test the effect of various moderators, as well as the causal role of a complementary manipulation of reflection – a component of rumination in which attention is focused on the issue at hand rather than one’s emotions.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/y82bs
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Uscinski, J., Enders, A., Klofstad, C., Seelig, M., Drochon, H., Premaratne, K. & Murthi, M. (2022) Have beliefs in conspiracy theories increased over time? PLOS ONE 17: e0270429. https://doi.org/10.1371/journal.pone.0270429

2. Liekefett, L. Sebben, S. & Becker, J. C. (2023). Does Brooding Meaningfully Increase the Likelihood of Believing in a Conspiracy? Stage 1 Registered Report, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/y82bs
Does Brooding Meaningfully Increase the Likelihood of Believing in a Conspiracy? A Registered ReportLuisa Liekefett, Simone Sebben, Julia C. Becker<p>This project aims to investigate the relationship between rumination and conspiracy beliefs. It<br>involves four pilot studies, including one observational and three experimental studies, but the<br>results were inconclusive. We suggest that ru...Humanities, Social sciencesChris Chambers2023-02-01 14:47:09 View
04 Dec 2023
STAGE 2
(Go to stage 1)

The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered Report

Brooding increases conspiracy beliefs but with practical significance to be determined

Recommended by ORCID_LOGO based on reviews by Matt Williams and Daniel Toribio-Flórez
The world is seemingly awash with conspiracy theories – from well-trodden examples such as fake Moon landings, the 9/11 truth movement, and Holocaust denial, to relative newcomers including COVID as a bioweapon, QAnon, and the belief that the science of climate change has been invented or falsified. While there is a public perception that conspiracy theories are becoming more prevalent, recent evidence suggests that the rate of conspiracism is relatively stable over time (Uscinski et al., 2022). At any point in history, it seems that a certain proportion of people find themselves vulnerable to conspiracy beliefs, but what distinguishes those who do from those who don’t, and what are the causal factors?
 
In the current study, Liekefett et al. (2023) investigated the critical role of rumination – a perseverative and repetitive focus on negative content leading to emotional distress. In particular, the authors asked whether one component of rumination referred to as brooding (dwelling on one’s worries and distressing emotions) has a specific causal role in the formation of conspiracy beliefs. In a series of preliminary experiments, the authors first established a procedure for successfully inducing rumination, identifying various boundary conditions and requirements for a successful design. In the main study (N=1,638 to 2,007 depending on the analysis), they asked whether the induction of brooding causes a significant increase in conspiracy beliefs. Manipulation checks were also included to confirm intervention fidelity (independently of this hypothesis), and exploratory analyses tested the effect of various moderators, as well as the causal role of a complementary manipulation of reflection – a component of rumination in which attention is focused on the issue at hand rather than one’s emotions.
 
As expected by the authors' preliminary work, manipulation checks independently confirmed the effectiveness of the brooding intervention. In answer to the main research question, participants who brooded over the worries and negative emotions associated with an issue were more susceptible to conspiracy beliefs compared to a control group. However, while this effect of brooding was statistically significant, the confidence interval of the effect size estimate overlapped with the authors' proposed smallest effect size of interest (d = 0.20), suggesting that the practical value of the effect remains to be determined.
 
Overall the findings are consistent with a range of psychological theories suggesting that rumination induces negative affect and/or narrows attention to negative information, which in turn may make conspiracy theories seem more probable and render individuals more vulnerable to cognitive bias. The authors note the importance of future work to define the smallest effect of practical significance, analagous to the criteria used to determine the 'minimal clinically important difference’ in medical research.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/y82bs
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Uscinski, J., Enders, A., Klofstad, C., Seelig, M., Drochon, H., Premaratne, K. & Murthi, M. (2022) Have beliefs in conspiracy theories increased over time? PLOS ONE 17: e0270429. https://doi.org/10.1371/journal.pone.0270429

2. Liekefett, L. Sebben, S. & Becker, J. C. (2023). The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered Report. Acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/3e8wc
The Effect of Brooding about Societal Problems on Conspiracy Beliefs: A Registered ReportLuisa Liekefett, Simone Sebben, Julia C. Becker<p>This Stage 2 Registered Report concerns the relationship between rumination, a repetitive style of negative thinking, and conspiracy beliefs (Stage 1 protocol: https://osf.io/y82bs, date of in-principle-acceptance: 23/05/2023). Based on four pi...Humanities, Social sciencesChris Chambers2023-10-19 17:46:59 View
27 Mar 2023
STAGE 1
article picture

Optimizing Esports Performance Using a Synergistic Mindsets Intervention

Synergistic Mindset Intervention for Competitive Situations

Recommended by ORCID_LOGO based on reviews by Lee Moore, Ivan Ropovik , Ivana Piterová and Jacob Keech
Mindset theories suggest that the mere belief in the malleability of human abilities can already help one to develop related performance. On the other hand, one and the same performance situation can also be experienced in various affective ways, which differently contribute to performance outcomes. Arguably, appraising a performance situation as a “threat” instead of “challenge” is associated with maladaptive responses, such as impaired cardiovascular mobilization. If people could experience performance situations as positive challenges, this might also improve performance outcomes. Drawing from these connected theoretical premises, the synergistic mindset intervention was developed and tentatively found to help adolescents in stressful situations (Yeager et al., 2022).
 
In the present registered report, Behnke et al. (2023) build on the above and test whether the synergistic mindset intervention can help individuals in competitive gaming situations. The authors utilize one of the leading esport games, Counter-Strike: Global Offensive​, and recruit its active players into randomized control and intervention groups for two weeks. Ultimately, the participants compete in a cash-prize tournament involving measures of affective experience and cardiovascular responses. Behnke et al. (2023) hypothesize that the synergistic mindset group will show greater challenge affective responses and superior performance outcomes. As such, the study design has significant potential to generate valuable evidence for various theoretical models and the synergistic mindset model in particular.
 
The Stage 1 manuscript was evaluated over two rounds by four experts with experimental psychology specializations in mindsets, stress, and statistics. Based on the comprehensive responses to the reviewers' feedback, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/z3adb
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals: 
 
 
References
 
Behnke M., Lakens D., Petrova K., Chwiłkowska P., Kaczmarek L. D., Jamieson J. P., & Gross J. J. (2023) Optimizing Esports Performance Using a Synergistic Mindsets Intervention. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/z3adb

Yeager D.S., Bryan C.J., Gross J.J., Murray J., Krettek D., Santos P., ... & Jamieson J.P. (2022) A synergistic mindsets intervention protects adolescents from stress. Nature 607, 512–520. https://doi.org/10.1038/s41586-022-04907-7
Optimizing Esports Performance Using a Synergistic Mindsets InterventionMaciej Behnke, Daniël Lakens, Kate Petrova, Patrycja Chwiłkowska, Lukasz D. Kaczmarek, Jeremy P. Jamieson, James J. Gross<p>Affective responses during stressful high-stakes situations can play an important role in shaping performance outcomes. For example, feeling shaky and nervous at a job interview can undermine performance, whereas feeling pumped and excited duri...Social sciencesVeli-Matti Karhulahti2023-01-04 10:12:55 View
08 Apr 2024
STAGE 2
(Go to stage 1)

Applying a Synergistic Mindsets Intervention to an Esports Context

Synergistic Mindset Intervention in Competitive Situations

Recommended by ORCID_LOGO based on reviews by Lee Moore, Ivan Ropovik and Jacob Keech
Mindset theories suggest that the mere belief in the malleability of human abilities can help one to develop related performance. On the other hand, one and the same performance situation can also be experienced in various affective ways, which differently contribute to performance outcomes. One theoretically justifiable premise is that appraising a performance situation as a “threat” instead of “challenge” is associated with maladaptive responses, such as impaired cardiovascular mobilization. If people could experience performance situations as positive challenges, this might also improve performance outcomes. Drawing from these connected premises, the synergistic mindset intervention was developed and tentatively found to help adolescents in stressful situations (Yeager et al., 2022).
 
In the present registered report, Behnke et al. (2024) built on the above to test whether the synergistic mindset intervention can help individuals in competitive gaming situations. The authors utilized one of the leading esport games, Counter-Strike: Global Offensive​, and recruited its active players (N=300) into randomized control and intervention groups. The participants competed in a cash-prize tournament involving measures of affective experience and cardiovascular responses. Behnke et al. (2024) hypothesized the synergistic mindset group (SMI) to show greater challenge affective responses and superior performance outcomes. 
 
Although the SMI produced a number of positive outcomes such as more beneficial stress mindsets, the hypotheses were not corroborated but the results supported a null. This may be related to the observation that participants generally experienced the intervention positively, which, in turn, limits the potential for improving affective and physiological responses. These rigorous null results are informative by directing the SMI research program toward test designs where more participants experience strong negative stress responses. Moreover, the results encourage researchers to reassess the underlying auxiliary hypotheses regarding affective responses and performance outcomes, the relationships of which may be complicated by situational factors that are not yet fully understood.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Three out of the four Stage 1 experts returned to review and, due to the study’s exceptionally high level of transparency, the reviewers had only minor requests for revision. As all the requested revisions were implemented carefully, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/z3adb
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals: 
 
 
References
 
1. Behnke M., Lakens D., Petrova K., Chwiłkowska P., Kaczmarek L. D., Jamieson J. P., & Gross J. J. (2024) Applying a Synergistic Mindsets Intervention to an Esports Context. Acceptance of Version 2 by Peer Community in Registered Reports https://osf.io/53z8e
 
2. Yeager D.S., Bryan C.J., Gross J.J., Murray J., Krettek D., Santos P., ... & Jamieson J.P. (2022) A synergistic mindsets intervention protects adolescents from stress. Nature 607, 512–520. https://doi.org/10.1038/s41586-022-04907-7
 
Applying a Synergistic Mindsets Intervention to an Esports ContextMaciej Behnke, Daniël Lakens, Kate Petrova, Patrycja Chwiłkowska, Szymon Jęśko Białek, Maciej Kłoskowski, Wadim Krzyżaniak, Patryk Maciejewski, Lukasz D. Kaczmarek, Kacper Szymański, Jeremy P. Jamieson, James J. Gross<p>Affective responses during stressful, high-stakes situations can play an important role in shaping performance. For example, feeling shaky and nervous at a job interview can undermine performance, whereas feeling excited during that same interv...Social sciencesVeli-Matti Karhulahti2024-02-02 17:57:13 View
29 Sep 2021
STAGE 1

Evaluating the pedagogical effectiveness of study preregistration in the undergraduate dissertation: A Registered Report

Does incorporating open research practices into the undergraduate curriculum decrease questionable research practices?

Recommended by ORCID_LOGO and ORCID_LOGO based on reviews by Kelsey McCune, Neil Lewis, Jr., Lisa Spitzer and 1 anonymous reviewer

In a time when open research practices are becoming more widely used to combat questionable research practices (QRPs) in academia, this Stage 1 Registered Report by Pownall and colleagues (2021) will empirically investigate the practice of preregistering study plans, which will allow us to better understand to what degree such practices increase awareness of QRPs and whether experience with preregistration helps reduce engagement in QRPs. This investigation is timely because results from these kinds of studies are only recently becoming available and the conclusions are providing evidence that open research practices can improve research quality and reliability (e.g., Soderberg et al. 2020, Chambers & Tzavella 2021). The authors crucially focus on the effect of preregistering the undergraduate senior thesis (of psychology students in the UK), which is a key stage in the development of an academic. This data will help shape the future of how we should teach open research practices and what effect we as teachers can have on budding research careers. The five expert peer reviews were of an extremely high quality and were very thorough. The authors did an excellent job of addressing all of the comments in their responses and revised manuscript versions, which resulted in only one round of peer review, plus a second revision based on Recommender feedback. As such, this registered report meets the Stage 1 criteria and is therefore awarded in-principle acceptance (IPA). We wish the authors the best of luck with the study and we look forward to seeing the results.

URL to the preregistered Stage 1 protocol: https://osf.io/9hjbw

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly journals:

References

  1. Pownall M, Pennington CR, Norris E, Clark K. 2021. Evaluating the pedagogical effectiveness of study preregistration in the undergraduate dissertation: A Registered Report. OSF, stage 1 preregistration, in principle acceptance of version 1 by Peer Community in Registered Reports.   https://doi.org/10.17605/OSF.IO/9HJBW
  2. Chambers C, Tzavella L (2021). The past, present, and future of Registered Reports. https://doi.org/10.31222/osf.io/43298
  3. Soderberg CK, Errington TM, Schiavone SR, Bottesini J, Thorn FS, Vazire S, Esterling KM, Nosek BA (2021) Initial evidence of research quality of registered reports compared with the standard publishing model. Nature Human Behaviour, 5, 990–997. https://doi.org/10.1038/s41562-021-01142-4
Evaluating the pedagogical effectiveness of study preregistration in the undergraduate dissertation: A Registered Report Madeleine Pownall; Charlotte R. Pennington; Emma Norris; Kait Clark <p style="text-align: justify;">Research shows that questionable research practices (QRPs) are present in undergraduate final-year dissertation projects. One entry-level Open Science practice proposed to mitigate QRPs is ‘study preregistration’, t...Life Sciences, Social sciencesCorina Logan2021-07-08 15:27:24 View
18 Aug 2023
STAGE 2
(Go to stage 1)

Evaluating the Pedagogical Effectiveness of Study Preregistration in the Undergraduate Dissertation

Incorporating open research practices into the undergraduate curriculum increases understanding of such practices

Recommended by ORCID_LOGO based on reviews by Kelsey McCune, Neil Lewis, Jr., Lisa Spitzer and 1 anonymous reviewer
In a time when open research practices are becoming more widely used to combat questionable research practices (QRPs) in academia, this Registered Report by Pownall and colleagues (2023) empirically investigated the practice of preregistering study plans, which allows us to better understand to what degree such practices increase awareness of QRPs and whether experience with preregistration helps reduce engagement in QRPs. This investigation is timely because results from these kinds of studies are only recently becoming available and the conclusions are providing evidence that open research practices can improve research quality and reliability (e.g., Soderberg et al. 2021, Chambers & Tzavella 2022). The authors crucially focused on the effect of preregistering the undergraduate senior thesis (of psychology students in the UK), which is a key stage in the development of an academic.
 
Pownall and colleagues found that preregistration did not affect attitudes toward QRPs, but it did improve student understanding of open research practices. Using exploratory analyses, they additionally found that those who preregistered were those students who reported that they had more opportunity, motivation, and greater capability. This shows how important it is to incorporate the teaching of open research practices such that students can increase their capability, motivation, and opportunity to pursue such practices, whether it is preregistration or other practices that are better known to reduce QRPs (such as registered reports; Krypotos et al. 2022). 
 
After four rounds of review and revisions, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/9hjbw
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Chambers C. D. & Tzavella, L. (2022). The past, present, and future of Registered Reports. Nature Human Behaviour, 6, 29-42. https://doi.org/10.1038/s41562-021-01193-7
 
2. Krypotos, A. M., Mertens, G., Klugkist, I., & Engelhard, I. M. (2022). Preregistration: Definition, advantages, disadvantages, and how it can help against questionable research practices. In Avoiding Questionable Research Practices in Applied Psychology (pp. 343-357). Cham: Springer International Publishing.
 
3. Pownall, M., Pennington, C. R., Norris, E., Juanchich, M., Smaile, D., Russell, S., Gooch, D., Rhys Evans, T., Persson, S., Mak, M. H. C., Tzavella, L., Monk, R., Gough, T., Benwell, C. S. Y., Elsherif, M., Farran, E., Gallagher-Mitchell, T., Kendrick, L. T., Bahnmueller, J., Nordmann, E., Zaneva, M., Gilligan-Lee, K., Bazhydai, M., Jones, A., Sedgmond, J., Holzleitner, I., Reynolds, J., Moss, J., Farrelly, D., Parker, A. J. & Clark, K. (2023). Evaluating the pedagogical effectiveness of study preregistration in the undergraduate dissertation [Stage 2 Registered Report], acceptance of Version 4 by Peer Community in Registered Reports. https://psyarxiv.com/xg2ah
 
4. Soderberg C. K., Errington T. M., Schiavone S. R., Bottesini J., Thorn F. S., Vazire S., Esterling K. M. & Nosek B. A. (2021) Initial evidence of research quality of registered reports compared with the standard publishing model. Nature Human Behaviour, 5, 990–997. https://doi.org/10.1038/s41562-021-01142-4
Evaluating the Pedagogical Effectiveness of Study Preregistration in the Undergraduate DissertationMadeleine Pownall, Charlotte R. Pennington, Emma Norris, Marie Juanchich, David Smaile, Sophie Russell, Debbie Gooch, Thomas Rhys Evans, Sofia Persson, Matthew HC Mak, Loukia Tzavella, Rebecca Monk, Thomas Gough, Christopher SY Benwell, Mahmoud El...<p>Research shows that questionable research practices (QRPs) are present in undergraduate final-year dissertation projects. One entry-level Open Science practice proposed to mitigate QRPs is ‘study preregistration’, through which researchers outl...Life Sciences, Social sciencesCorina Logan2023-03-25 11:38:54 View
22 Jul 2024
STAGE 1
article picture

Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”

Replicating, Revising and Reforming: Unpicking the Apparent Nanoparticle Endosomal Escape Paradox

Recommended by and ORCID_LOGO based on reviews by Cecilia Menard-Moyon and Zeljka Krpetic
Context
 
Over the past decade there has been an exponential increase in the number of research papers utlising nanoparticles for biological applications such as intracellular sensing [1, 2], theranostics [3-5] and more recently drug delivery and precision medicine [6, 7]. Despite the success stories, there is a disconnect regarding current dogma on issues such as nanoparticle uptake and trafficking, nanoparticle delivery via the enhanced permeability and retention (EPR) effect, and endosomal escape. Critical re-evaluation of these concepts both conceptually and experimentally is needed for continued advancement in the field.
 
For this preregistration, Said et al. (2024) focus on nanoparticle intracellular trafficking, specifically endosomal escape [8]. The current consensus in the literature is that nanoparticles enter cells via endocytosis [9, 10] but reportedly just 1-2% of nanoparticles/ nanoparticle probes escape endosomes and enter the cytoplasm [11-13]. There is therefore an apparent paradox over how sensing nanoparticles can detect their intended targets in the cytoplasm if they are trapped within the cell endosomes. To address this fundamental issue of nanoparticle endosomal escape, Lévy and coworkers are carrying out replication studies to thoroughly and transparently replicate the most influential papers in the field of nanoparticle sensing. The aim of these replication studies is twofold: to establish a robust methodology to study endosomal escape of nanoparticles, and to encourage discussions, transparency and a step-change in the field.  
 
Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”
 
For this replication study, the authors classified papers on the topic of nanoparticle sensing and subsequently ranked them by number of citations.  Based on this evaluation they selected a paper by Zhu and colleagues [14] entitled “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions” for their seminal replication study.  To determine the reproducibility of the results from Zhu et al., the authors aim to establish the proportion of endosomal escape of the nanoparticles, and to examine the data in a biological context relevant to the application of the probe.
 
Beyond Replication
 
The authors plan to replicate the exact conditions reported in the materials and methods section of the selected paper such as nanoparticle probe synthesis of CdSe@C-TPEA nanoparticles, assessment of particle size, stability and reactivity and effect on cells (TEM, pH experiments, fluorescent responsivity to metal ions and cell viability). In addition, Said et al., plan to include further experimental characterisation to complement the existing study by Zhu and colleagues. They will incorporate additional controls and methodology to determine the intracellular location of nanoparticle probes in cells including: quantifying excess fluorescence in the culture medium, live cell imaging analysis, immunofluorescence with endosomal and lysosomal markers, and electron microscopy of cell sections. The authors will also include supplementary viability studies to assess the impact of the nanoparticles on HeLa cells as well as an additional biologically relevant cell line (for use in conjunction with the HeLa cells as per the original paper).
 
The Stage 1 manuscript underwent two rounds of thorough in-depth review. After considering the detailed responses to the reviewers' comments, the recommenders  determined that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).  
 
The authors have thoughtfully considered their experimental approach to the replication study, whilst acknowledging any potential limitations. Given that conducting such a replication study is novel in the field of Nanotechnology and there is currently no ‘gold standard’ approach in doing so, the authors have showed thoughtful regard of statistical analysis and unbiased methodology where possible.
 
Based on current information, this study is the first use of preregistration via Peer Community in Registered Reports and the first formalised replication study in Nanotechnology for Biosciences. The outcomes of this of this study will be significant both scientifically and in the wider context in discussion of the scientific method.
 
URL to the preregistered Stage 1 protocol: https://osf.io/qbxpf
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly Journals:
 
References
 
1. Howes, P. D., Chandrawati, R., & Stevens, M. M. (2014). Colloidal nanoparticles as advanced biological sensors. Science, 346(6205), 1247390. https://doi.org/10.1126/science.1247390
 
2. Liu, C. G., Han, Y. H., Kankala, R. K., Wang, S. B., & Chen, A. Z. (2020). Subcellular performance of nanoparticles in cancer therapy. International Journal of Nanomedicine, 675-704. https://doi.org/10.2147/IJN.S226186
 
3. Tang, W., Fan, W., Lau, J., Deng, L., Shen, Z., & Chen, X. (2019). Emerging blood–brain-barrier-crossing nanotechnology for brain cancer theranostics. Chemical Society Reviews, 48(11), 2967-3014. https://doi.org/10.1039/C8CS00805A
 
4. Yoon, Y. I., Pang, X., Jung, S., Zhang, G., Kong, M., Liu, G., & Chen, X. (2018). Smart gold nanoparticle-stabilized ultrasound microbubbles as cancer theranostics. Journal of Materials Chemistry B, 6(20), 3235-3239. https://doi.org/10.1039%2FC8TB00368H
 
5. Lin, H., Chen, Y., & Shi, J. (2018). Nanoparticle-triggered in situ catalytic chemical reactions for tumour-specific therapy. Chemical Society Reviews, 47(6), 1938-1958. https://doi.org/10.1039/C7CS00471K
 
6. Hou, X., Zaks, T., Langer, R., & Dong, Y. (2021). Lipid nanoparticles for mRNA delivery. Nature Reviews Materials, 6(12), 1078-1094. https://doi.org/10.1038/s41578-021-00358-0
 
7. Mitchell, M. J., Billingsley, M. M., Haley, R. M., Wechsler, M. E., Peppas, N. A., & Langer, R. (2021). Engineering precision nanoparticles for drug delivery. Nature Reviews Drug Discovery, 20(2), 101-124. https://doi.org/10.1038/s41573-020-0090-8
 
8. Said, M., Gharib, M., Zrig, S., & Lévy, R. (2024). Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/qbxpf
 
9. Behzadi, S., Serpooshan, V., Tao, W., Hamaly, M. A., Alkawareek, M. Y., Dreaden, E. C., ... & Mahmoudi, M. (2017). Cellular uptake of nanoparticles: Journey inside the cell. Chemical Society Reviews, 46(14), 4218-4244. https://doi.org/10.1039/C6CS00636A
 
10. de Almeida, M. S., Susnik, E., Drasler, B., Taladriz-Blanco, P., Petri-Fink, A., & Rothen-Rutishauser, B. (2021). Understanding nanoparticle endocytosis to improve targeting strategies in nanomedicine. Chemical society reviews, 50(9), 5397-5434. https://doi.org/10.1039/D0CS01127D
 
11. Smith, S. A., Selby, L. I., Johnston, A. P., & Such, G. K. (2018). The endosomal escape of nanoparticles: toward more efficient cellular delivery. Bioconjugate Chemistry, 30(2), 263-272. http://dx.doi.org/10.1021/acs.bioconjchem.8b00732
 
12. Cupic, K. I., Rennick, J. J., Johnston, A. P., & Such, G. K. (2019). Controlling endosomal escape using nanoparticle composition: current progress and future perspectives. Nanomedicine, 14(2), 215-223. https://doi.org/10.2217/nnm-2018-0326
 
13. Wang, Y., & Huang, L. (2013). A window onto siRNA delivery. Nature Biotechnology, 31(7), 611-612. https://doi.org/10.1038/nbt.2634
 
14. Zhu, A., Qu, Q., Shao, X., Kong, B., & Tian, Y. (2012). Carbon-dot-based dual-emission nanohybrid produces a ratiometric fluorescent sensor for in vivo imaging of cellular copper ions. Angewandte Chemie (International ed. in English), 51(29), 7185-7189. https://doi.org/10.1002/anie.201109089
Replication of “Carbon-Dot-Based Dual-Emission Nanohybrid Produces a Ratiometric Fluorescent Sensor for In Vivo Imaging of Cellular Copper Ions”Maha Said, Mustafa Gharib, Samia Zrig, Raphaël Lévy <p>In hundreds of articles published over the past two decades, nanoparticles have been described as probes for sensing and imaging of a variety of intracellular cytosolic targets. However, nanoparticles generally enter cells by endocytosis with o...Life Sciences, Medical Sciences, Physical SciencesEmily Linnane2023-11-29 19:14:03 View
02 Dec 2022
STAGE 1

Revisiting the link between anthropomorphism and loneliness with an extension to free will belief: Replication and extensions of Epley et al. (2008)

Are loneliness and free will beliefs associated with anthropomorphism?

Recommended by ORCID_LOGO based on reviews by John Protzko and Marieke Wieringa
Anthropomorphism is a widespread phenomenon in which people instil non-human entities or objects with human-like characteristics, such as motivations, intentions, and goals. Although common, the tendency to anthropomorphise varies between people, and a growing body of psychological research has examined the importance of various individual differences. One major theoretical account of anthropomorphism (Epley et al. 2007) suggests that sociality motivation – the drive to establish social relationships – is a key moderator of the phenomenon. In support of this account, some evidence suggests that people who experience greater loneliness (a proposed marker of sociality motivation) are more likely to anthropomorphise. In an influential series of studies, Epley et al. (2008) found that anthropomorphism and loneliness were positively correlated and that inducing participants experimentally to feel more lonely led to greater anthropomorphism. Later studies, however, produced more mixed results, particularly concerning the effectiveness of the experimental interventions.
 
In the current study, Elsherif et al. (2022) propose a partial replication of Epley et al. (2008), focusing on the correlational relationship between anthropomorphism and loneliness, with extensions to examine free will beliefs, anthropomorphism for supernatural beings (in addition to objects/gadgets), and the extent to which participants judged objects/gadgets to be controllable.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/by89c
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Epley, N., Waytz, A., & Cacioppo, J. T. (2007). On seeing human: A three-factor theory of anthropomorphism. Psychological Review, 114, 864–886. https://doi.org/10.1037/0033-295X.114.4.864 
 
2. Epley, N., Akalis, S., Waytz, A., & Cacioppo, J. T. (2008). Creating social connection through inferential reproduction: Loneliness and perceived agency in gadgets, Gods, and greyhounds. Psychological Science, 19, 114–120. https://doi.org/10.1111/j.1467-9280.2008.02056.x 
 
3. Elsherif, M., Pomareda, C., Xiao, Q., Chu, H. Y., Tang, M. C., Wong, T. H., Wu, Y. &  Feldman, G. (2022). Revisiting the positive association between loneliness and anthropomorphism with an extension to belief in free will: Replication and extensions of Epley et al. (2008), in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/by89c
Revisiting the link between anthropomorphism and loneliness with an extension to free will belief: Replication and extensions of Epley et al. (2008)Mahmoud Elsherif, Christina Pomareda, Qinyu Xiao, Hoi Yan Chu, Ming Chun Tang, Ting Hin (Angus) Wong, Yiming Wu, Gilad Feldman<p>This is a scheduled PCI-RR snap shot for a planned project: "Revisiting the link between anthropomorphism and loneliness with an extension to free will belief: Replication and extensions of Epley et al. (2008)​"</p>Social sciencesChris Chambers2022-02-16 07:03:50 View
25 Sep 2024
STAGE 2
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Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions Registered Report of Baron and Szymanska (2011)

Understanding biases and heuristics in charity donations

Recommended by ORCID_LOGO based on reviews by Amanda Geiser and Jonathan Berman

Decisions to give to charities are affected by numerous external and internal factors. Understanding the elements influencing donation decisions is of first-order importance for science and society. On the scientific side, understanding the determinants of charity-giving contributes to the knowledge of altruistic behaviors in the presence of collective problems such as poverty, climate change, or animal welfare. On the social side, pointing out which factors affect donations can help increase prosocial behaviors and might facilitate collective actions in the case of public goods.  

Previous work has identified multiple mechanisms affecting altruistic donations to charities (Bekkers and Wiepking, 2011). Importantly, Baron and Szymanska (2011) collected empirical evidence suggesting that people prefer (i) their donations to be directly used for projects rather than organizational costs, (ii) when charities have low past costs, (iii) to diversity their donations into several NGOs, (iv) to favor charities that deal with close peers like nationals, and (v) to give voluntarily rather than through taxes. 

Here, Chan and Feldman (2024) conducted a close replication of Studies 1 to 4 of Baron and Szymanska (2011) using a large sample of online participants (four studies, overall N=1,403). In their replication, the authors found supporting evidence for the phenomena reported in the original study. In particular, people were more likely to donate to charities with lower organizational and lower past costs, to diversify their donations, and to show ingroup/nationalist preferences with larger donations to NGOs helping local over foreign children. Chan and Feldman (2024) ran additional analyses that indicated validity concerns regarding the analysis and questions that resulted in finding a preference for voluntary donations over taxation. In their added extensions that went beyond the original study, they also found that donors preferred to donate to charities whose overhead costs are paid for by other donors and unexpected evidence that making donations anonymous increased rather than decreased contributions.

The Stage 2 manuscript was evaluated over one round of in-depth review by the recommender and two expert reviewers. Following revision, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/gmswz
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Baron, J. and Szymanska, E. (2011). Heuristics and Biases in Charity. In D. M. Oppenheimer and C. Y. Olivola (Eds.), The Science of Giving: Experimental Approaches to the Study of Charity (pp. 215–235). Psychology Press. https://doi.org/10.4324/9780203865972
 
2. Bekkers, R. and Wiepking, P. (2011). A Literature Review of Empirical Studies of Philanthropy. Nonprofit and Voluntary Sector Quarterly, 40, 924–973. https://doi.org/10.1177/0899764010380927
 
3. Chan, M. and Feldman, G. (2024). Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions Registered Report of Baron and Szymanska (2011) [Stage 2]. Acceptance of Version 5 by Peer Community in Registered Reports. https://osf.io/4etkp
Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions Registered Report of Baron and Szymanska (2011)Mannix Chan, Gilad Feldman<p>Individuals who donate to charity may be affected by various biases and donate inefficiently. In a replication and extension Registered Report with a US Amazon Mechanical Turk sample using CloudResearch (N = 1403), we replicated Studies 1 to 4 ...Social sciencesRomain Espinosa2024-04-27 02:28:49 View
11 Jul 2023
STAGE 1

Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions of Baron and Szymanska (2011)

Understanding biases and heuristics in charity donations

Recommended by ORCID_LOGO based on reviews by Amanda Geiser and Jonathan Berman ?
Decisions to give to charities are affected by numerous external and internal factors. Understanding the elements that influence donation decisions is of first-order importance for science and society. On the scientific side, understanding the determinants of charity giving contributes to the knowledge of altruistic behaviors in the presence of collective problems such as poverty, climate change, or animal welfare. On the social side, pointing out which factors affect donations can help increase pro-social behaviors and might facilitate collective actions in the case of public goods. 
 
Previous work identified multiple mechanisms affecting altruistic donations to charities (Bekkers and Weeping, 2011). Importantly, Baron and Szymanska (2011) collected empirical evidence suggesting that people prefer (i) their donations to be directly used for projects rather than organizational costs, (ii) when charities have low past costs, (iii) to diversity their donations into several NGOs, (iv) to favor charities that deal with close peers like nationals, and (v) to give voluntarily rather than through taxes. 
 
In the current study, Chan and Feldman seek to replicate the results of Baron and Szymanska (2011). They propose a close replication of the original study using a large sample of online participants (1,400 participants). In addition to the five mechanisms identified by the original study, they will further explore whether public donation increases contributions and whether individuals are more likely to donate when the charities’ overhead costs are paid for by other donors. 
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/gmswz
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Baron, J. & Szymanska, E. (2011). Heuristics and Biases in Charity. In D. M. Oppenheimer & C. Y. Olivola (Eds.), The Science of Giving: Experimental Approaches to the Study of Charity (pp. 215–235). Psychology Press. 
 
2. Bekkers, R. & Wiepking, P. (2011). A Literature Review of Empirical Studies of Philanthropy. Nonprofit and Voluntary Sector Quarterly, 40, 924–973.
 
3. Chan, M. & Feldman, G. (2023). Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions Registered Report of Baron and Szymanska (2011), in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/gmswz
Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions of Baron and Szymanska (2011)Mannix CHAN, Gilad FELDMAN<p>This is a scheduled PCI-RR snap shot for a planned project: "Factors impacting effective altruism: Revisiting heuristics and biases in charity in a replication and extensions of Baron and Szymanska (2011)​​"</p>Social sciencesRomain Espinosa2023-02-28 13:19:52 View