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Id▼Title * Authors * Abstract * PictureThematic fields * RecommenderReviewersSubmission date
13 Jul 2023
STAGE 1

Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered report

Neurocognitive insights on instructed extinction in the context of pain

Recommended by ORCID_LOGO based on reviews by Tom Beckers, Gaëtan Mertens and Karita Ojala
Rapid learning in response to pain is a crucial survival mechanism, relying on forming associations between cues in the environment and subsequent pain or injury. Existing evidence suggests that associations between conditioned stimuli (cues) and unconditioned aversive stimuli (such as pain) are learned faster than for appetitive stimuli that signal pain relief. In addition, when the link between a conditioned and unconditioned stimulus is broken (by unpairing them), the extinction of this learning effect is slower for aversive that appetitive stimuli, resulting in a flatter extinction slope. Understanding why extinction slopes are reduced for aversive stimuli is important for advancing theoretical models of learning, and for devising ways of increasing the slope (and thus facilitating extinction learning) could help develop more effective methods of pain relief, particularly in the treatment of chronic pain.
 
In the current programmatic submission, Busch et al. (2023) will undertake two Registered Reports to test whether a verbal instruction intervention that explicitly informs participants about contingency changes between conditioned and unconditioned stimuli facilitates extinction learning, especially for aversive (painful) stimuli, and how changes in extinction learning relate to neural biomarkers of functional connectivity. In the first Registered Report, they will initially seek to replicate previous findings including faster acquisition of aversive than appetitive conditioned stimuli as well as incomplete extinction of aversive conditioned stimuli without verbal instruction. They will then test how the instruction intervention alters extinction slopes and the completeness of extinction for appetitive and aversive stimuli, using a range of behavioral measures (expectancy and valence ratings) and physiological measures (pupillometry, skin conductance responses). To shed light on the neural correlates of these processes, in the second Registered Report the authors will use functional magnetic resonance imaging (fMRI) to ask firstly how acquisition and extinction of aversive and appetitive conditioned responses are related to resting state brain connectivity within a network that includes ventromedial prefrontal cortex, amygdala, and striatum, and secondly, whether the effectiveness of instruction on extinction learning is associated with differences in resting state connectivity across this network.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/cj75p (under temporary private embargo)
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Busch, L., Wiech, K., Gamer, M., Knicses, B., Spisak, T., Schmidt, K., & Bingel, U. (2023). Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered report. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/cj75p
Modulatory effects of instructions on extinction efficacy in appetitive and aversive learning: A registered reportLea Busch, Katja Wiech, Matthias Gamer, Balint Kincses, Tamas Spisak, Katharina Schmidt, Ulrike Bingel<p>In the context of pain, extinction learning has been shown to be slower or incomplete for aversive compared to appetitive cues (i.e., cues signaling pain exacerbation and pain relief, respectively), potentially due to their higher biological re...Medical SciencesChris Chambers2022-10-15 19:45:48 View
14 Nov 2023
STAGE 1

Scrolling to wisdom: the impact of social media news exposure on knowledge perception

Might we know less about current events than we think we do?

Recommended by ORCID_LOGO based on reviews by Adrien Fillon, Erik Løhre and Moritz Ingendahl
​​We are bombarded with news about current events from multiple sources: print media, digital media, friends, family, and more. At the same time, there is an imperative to “stay informed” and be knowledgeable of happenings both local and global. But how much knowledge do we actually gain from this bombardment of information? How informed are we really? It turns out that our perceptions of our knowledge tends to overstate our actual knowledge of a topic. This “illusion of knowledge” effect has been studied across a wide variety of contexts, but is especially relevant for understanding how people learn about and interact with politicized topics.
 
In the current study, Ruzzante et al. (2023) propose to further our understanding of the illusion of knowledge effect in the context of news exposure on social media. They will use an online pre-post experimental design that assesses participants’ perceived knowledge of a number of topics prior to the manipulation, which involves exposure to different social media news feeds, coming two weeks later. Central to the study, participants will be randomized to news stories that differ in their degree of self-involvement, that is how emotionally involved the topics are. Ruzzante et al. will test the hypothesis that more highly self-involved topics (e.g., abortion) will lead to a greater illusion of knowledge effect than less self-involved topics (e.g., feline immunodeficiency).
 
The Stage 1 manuscript was evaluated over two rounds of in-depth peer review, the first consisting of substantial comments from three scholars with relevant expertise, and the second consisting of a close review by the recommender. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and was therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/qa7tb
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Ruzzante, F., Cevolani, G., & Panizza, F. (2023). Scrolling to wisdom: The impact of social media news exposure on knowledge perception. In principle acceptance of Version 5 by Peer Community in Registered Reports. https://osf.io/qa7tb
Scrolling to wisdom: the impact of social media news exposure on knowledge perceptionFederica Ruzzante, Gustavo Cevolani, Folco Panizza<p>The present study aims to test the effect of exposure to news in a social media environment on people’s perceived knowledge of selected topics and on the “illusion of knowledge” effect, i.e., the overestimation of one’s perceived knowledge rela...Social sciencesMoin Syed2022-10-12 21:16:51 View
15 Apr 2023
STAGE 1
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Reconstructing Gaming Disorder: A Taxonomy by Registered Report

How can the experiences of those who engage in video games in healthy and unhealthy ways be systematically organised?

Recommended by ORCID_LOGO based on reviews by Michelle Carras, Lukas J. Gunschera and Christopher Ferguson
People are often drawn into intensive video game use in ways they or others may find troubling, harmless or even praiseworthy. Understanding these different experiences may help with integrating intensive technology use into everyday life in a healthy way.
 
In this programmatic submission, Karhulahti et al. (2023) will explore the gaming experiences of three groups of people (those who have sought treatment for gaming, esport players, and adolescents who play around two hours every day), using phenomenological and clinical interviews, and gaming diary logs every four months over three years. Around 200-300 participants will be recruited initially from Finland, Slovakia, and South Korea. In order to further increase cross-cultural range, the study will apply a new duplication method to collect similar data also in countries that have been studied little in the past. The aim will be to answer the questions of a) Is it possible to distinguish passionate from pathological gaming by the meanings and values that players attach to videogame play? and b) What are the design structures of videogames, which are played intensively and/or with gaming-related health problems? Ultimately, the study aims to synthesise all its data into a new taxonomic system, which can help better understand the differences and idiosyncrasies of gaming in lives across cultures.
 
This Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on the comprehensive responses to the reviewers' feedback, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/ekm8x
 
Level of bias control achieved: Level 4. At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors (e.g. residing in a public database or with a colleague) BUT the authors certify that they have not yet accessed any part of that data/evidence
 
List of eligible PCI RR-friendly journals:
 
 
References
Karhulahti, V.-M., Martončik. M., Siutila, M., Park, S., Jin, J., Adamkovič, M., Auranen, T., Na, B., & Yoon, T.-J. (2023). Reconstructing Gaming Disorder: A Taxonomy by Registered Report​, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/ekm8x
Reconstructing Gaming Disorder: A Taxonomy by Registered ReportVeli-Matti Karhulahti, Marcel Martončik, Miia Siutila, Solip Park, Yaewon Jin, Matúš Adamkovič, Tiina Auranen, Bora Na, Tae-Jin Yoon<p style="text-align: justify;">Videogames have become one of the most prevalent cultural forms around the world. While their role in art, pedagogy, and everyday life keeps growing, the health debates on videogame play—gaming—culminated in 2022 wi...Humanities, Medical Sciences, Social sciencesZoltan Dienes Oluwaseyi Adeliyi, Abiola Akinnubi 2022-10-10 15:09:55 View
06 Feb 2023
STAGE 1

Investigating the impact of vascular risk factors on the progression of white matter lesions

Understanding predictors of white matter lesions in the human brain

Recommended by ORCID_LOGO based on reviews by Max Elliott, Isabel Garcia Garcia and 1 anonymous reviewer
Cerebral small vessel disease (CSVD) is a common and multi-faceted set of pathologies that affect the small arteries, arterioles, venules and capillaries of the brain. The disease manifests through a range of symptoms and conditions, including psychiatric disorders, abnormal gait, and urinary incontinence, while accounting for 25% of strokes and nearly 50% of dementia.
 
The presence of CSVD is associated with white matter lesions (WML) detected using neuroimaging, which have in turn been shown to predict future stroke, cognitive decline and dementia. While vascular risk factors of CSVD (such as hypertension and obesity) are also associated with CSVD, a complete picture of the predictive relationship between WML, cognitive decline, and blood pressure remains to be determined, as does the role of sex/gender. These inter-relationships are important to determine for improving the diagnosis and treatment of CSVD.
 
In the current study, Beyer et al. will analyse a large emerging dataset from the LIFE-Adult project – a longitudinal, two-wave, population-based study – to ask whether higher blood pressure predicts a greater increase in WML, and whether progression of WML is associated with measures of memory and executive function. In addition, the authors will explore the relationship between abdominal obesity and WML progression, and the extent to which WML progression, and its interaction with vascular risk factors, depends on sex/gender.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/qkbgj
 
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Beyer, F., Lammer, L., Loeffler, M., Riedel-Heller, S., Villringer, A. & Witte, V. (2023). Investigating the impact of vascular risk factors on the progression of white matter lesions, in principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/qkbgj
Investigating the impact of vascular risk factors on the progression of white matter lesionsFrauke Beyer,Laurenz Lammer, Markus Loeffler, Steffi Riedel-Heller, Arno Villringer, Veronica Witte<p>Cerebral small vessel disease (cSVD) is a major brain pathology contributing to cognitive decline and dementia. Vascular risk factors have been associated with imaging markers of cSVD such as white matter lesions, yet longitudinal studies have ...Life SciencesChris Chambers Max Elliott, Isabel Garcia Garcia2022-10-07 13:44:11 View
18 Jan 2023
STAGE 1
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Beneath the label: Assessing video games’ compliance with ESRB and PEGI loot box warning label industry self-regulation

How effective is self-regulation in loot box labelling?

Recommended by ORCID_LOGO based on reviews by Pete Etchells and Jim Sauer
Paid loot boxes – items bought for real-world money that offer randomised rewards – are a prevalent feature of contemporary video games (Zendle et al., 2020). Because they employ random chance to provide rewards after spending real money, loot boxes have been considered a form of gambling, raising concerns about risk of harm to children and other vulnerable users. In response, some countries have taken legal steps to regulate and even ban the use of loot boxes, with only limited success so far (Xiao, 2022). At the same time, the Entertainment Software Rating Board (ESRB) and PEGI (Pan-European Game Information) now expect games that contain loot boxes to be marked with warning labels that, in theory, will enable users (including parents) to make more informed decisions. These requirements by ESRB/PEGI are not legally binding and may be considered a form of industry self-regulation.
 
In the current study, Xiao (2023) will investigate the effectiveness of self-regulation in the use of loot box labels. Study 1 examines the consistency of warning labels by the ESRB and PEGI, with the expectation that if self-regulation works as it should then these labels should always (or nearly always) co-occur. Study 2 establishes the compliance rate for labelling among popular games that are known to contain loot boxes, with a rate of ≥95% considered to be successful. The findings should prove useful in identifying the success or failure of self-regulation as a means of ensuring industry compliance with loot box labelling.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/e6qbm
 
Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Zendle, D., Meyer, R., Cairns, P., Waters, S., & Ballou, N. (2020). The prevalence of loot boxes in mobile and desktop games. Addiction, 115(9), 1768-1772. https://doi.org/10.1111/add.14973

2. Xiao, L. Y. (2022). Breaking Ban: Belgium’s ineffective gambling law regulation of video game loot boxes. Stage 2 Registered Report, acceptance of Version 2 by Peer Community in Registered Reports. https://doi.org/10.31219/osf.io/hnd7w 
 
3. Xiao, L. Y. (2023). Beneath the label: Assessing video games’ compliance with ESRB and PEGI loot box warning label industry self-regulation, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/e6qbm
Beneath the label: Assessing video games’ compliance with ESRB and PEGI loot box warning label industry self-regulationLeon Y. Xiao<p>Loot boxes in video games are a form of in-game transactions with randomised elements. Concerns have been raised about loot boxes’ similarities with gambling and their potential harms (e.g., overspending). Recognising players’ and parents’ conc...Humanities, Social sciencesChris Chambers2022-09-17 00:14:51 View
17 Jan 2023
STAGE 1
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Similarities and differences in a global sample of song and speech recordings

Exploring cross-cultural variation in speech and song

Recommended by ORCID_LOGO based on reviews by Bob Slevc, Nai Ding and 1 anonymous reviewer
For centuries, the ubiquity of language and music across human societies has prompted scholars to speculate about their cross-cultural origins as well as their shared and unique characteristics. Depending on the extent to which contemporary theories emphasise the role of biology vs. culture, a range of hypotheses have been proposed concerning expected similarities and differences in song and speech. One class of hypotheses stemming from cultural relativism assumes a lack of universal regularities in song and speech, and therefore predicts no systematic cross-cultural relationships. On the other hand, more recent evolutionary hypotheses such as the social bonding hypothesis, motor constraint hypothesis, and sexual selection hypothesis all predict differences or similarities in specific characteristic of vocalisations, such as pitch regularity, pitch interval size, and melodic contour. Existing results are mixed in their support of these predictions.
 
In the current study, Ozaki et al. (2022) embark on an ambitious project to elucidate cross-cultural similarities and differences between speech and song in 81 different linguistic varieties spanning 23 language families. Understanding precisely how song and speech are related is methodologically challenging due to the multitude of confounds that can arise in comparing natural recordings. Here the authors overcome these difficulties with four types of carefully controlled recordings: singing, recitation of sung lyrics, spoken description of the song, and instrumental version of the sung melody. The authors will then examine six features that are amenable to reliable comparison, including pitch height, temporal rate, pitch stability, timbral brightness, pitch interval size, and pitch declination. With this data in hand, the authors will ask which acoustic features differ reliably between song and speech across cultures, with the expectation that song will exhibit higher pitch, slower rate and more stable pitch than speech. At the same time, the authors expect song and speech to be reliably similar in the characteristics of timbral brightness, pitch intervals and pitch contours. In addition to these confirmatory tests, the authors will explore variation across a range of additional stimulus characteristics and ancillary research questions.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/jdhtz
 
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question AND they have taken additional steps to maximise bias control and rigour.

List of eligible PCI RR-friendly journals:
 
 
References
 
1. Ozaki, Y., Savage P. E. et al. (2022). Similarities and differences in a global sample of song and speech recordings, in principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/jdhtz
Similarities and differences in a global sample of song and speech recordingsCorresponding authors: Yuto Ozaki and Patrick E. Savage (Keio University, Japan). Full list of 80 authors is in the manuscript<p>What, if any, similarities and differences between song and speech are consistent across cultures? Both song and speech are found in all known human societies and are argued to share evolutionary roots and cognitive resources, yet no studies ha...Social sciencesChris Chambers Bob Slevc, Nai Ding2022-09-16 16:03:10 View
11 Apr 2024
STAGE 1

Managing Disclosure Outcomes in Intelligence Interviews

Managing costs and rewards when choosing to disclose information

Recommended by ORCID_LOGO based on reviews by Jason Chin, Yikang Zhang and Tyler Jacobs
An interviewee in an intelligence interview can face competing interests in disclosing information: The value in cooperating because, for example, information given leads to the arrest of a narcotics gang, making the neighbourhood safer; and the risk that disclosing the information leads to reprisals from the gang. Different pieces of information will compete with each other for disclosure, depending on this balance of risks to self-interest. According to the disclosure-outcomes management model of Neequaye et al., information will be disclosed more with a high than low probability of reward, as might be straightforwardly expected, but this difference will be larger when there is a low probability of cost rather than a high probability. The high probability of cost will induce more a variable response to the possible benefits.

Neequaye et al. (2023) will invite participants to assume the role of an informant, with the goal of maximizing their points according to stated probabilities of costs and benefits of disclosing pieces of information relating to given scenarios. Then the degree to which each type of information is disclosed in a subsequent interview will be assessed: this way the crucial interaction can be tested.
 
The Stage 1 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/ru8j5

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Neequaye, D. A., Luke, T. J., & Kollback, K. (2023). Managing Disclosure Outcomes in Intelligence Interviews, in principle acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/ru8j5
Managing Disclosure Outcomes in Intelligence InterviewsDavid A. Neequaye, Timothy J. Luke, and Kristina Kollback, Department of Psychology, University of Gothenburg.<p>We introduce the disclosure-outcomes management model. The model views disclosure in intelligence interviews as a behavior interviewees use to profitably navigate self-interest dilemmas. We theorize that interviewees compare the potential outco...Social sciencesZoltan Dienes2022-09-15 15:03:59 View
21 May 2024
STAGE 1

The importance of consolidating perceptual experience and contextual knowledge in face recognition

How does perceptual and contextual information influence the recognition of faces?

Recommended by ORCID_LOGO based on reviews by Lisa DeBruine and Haiyang Jin
When we familiarise with new faces over repeated exposures, it is in situations that have meaning for us. Here, Noad and Andrews (2023) ask whether meaningful context during exposure matters for the consolidation of faces into long-term memory. Participants will be shown video clips from TV shows that are ordered either in their original chronological sequence, preserving meaningful context, or in a scrambled sequence. It is expected that the original sequence will provide a better understanding of the narrative. The critical question is whether this will also be associated with differences in memory for the faces. Memory will be tested with images of the actor from the original clips (‘in show’) or images of the same actor from another show (‘out-of-show’), both immediately after exposure and following a four-week delay. It is predicted that memory for faces will be better retained across the delay when the original exposure was in a meaningful context, and that this benefit will be enhanced for ‘in-show’ images, where the person’s appearance matches with the original context. The pre-registered predictions and the targeted effect sizes for this study are informed by pilot data reported within the manuscript.
 
The Stage 1 manuscript was evaluated through an initial round of editorial review, followed by a further round of external review, after which the recommender judged that it met the Stage 1 criteria for in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/8wp6f
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Noad, K. & Andrews, T. J. (2023). The importance of consolidating perceptual experience and contextual knowledge in face recognition, in principle acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/8wp6f
The importance of consolidating perceptual experience and contextual knowledge in face recognitionKira Noad and Timothy J. Andrews<p>Although the ability to recognise familiar faces is a critical part of everyday life, the process by which a face becomes familiar in the real world is not fully understood. Previous research has focussed on the importance of perceptual experie...Life SciencesRobert McIntosh2022-09-09 14:33:57 View
23 Jan 2023
STAGE 1

Genetically-modified animals as models of neurodevelopmental conditions: an umbrella review

Evaluating the quality of systematic reviews in preclinical animal studies of neurodevelopmental conditions

Recommended by ORCID_LOGO based on reviews by Marietta Papadatou-Pastou and Richel Bilderbeek
Single gene alterations have been estimated to account for nearly half of neurodevelopmental conditions (NDCs), providing a crucial opportunity for animal models to understand the underlying mechanisms, causes and potential treatments. The use of systematic reviews (SRs) can, in principle, provide a powerful means to synthesise this evidence-base; however, the reporting quality of previous SRs in preclinical animal research has been found lacking (Hunniford et al., 2021). In the current study, Wilson et al. (2023) will undertake an umbrella review – a systematic review of systematic reviews – to assess the characteristics and reporting quality of SRs that, in turn, synthesise research in genetically-modified animals to model NDCs. In particular, the authors will extract key features of reviews (including, among others, the aim and primary research questions, relevant animal model, and number of studies in the SR), in addition to quality indicators such as risk of bias and completeness of reporting. In doing so, the authors aim to enhance guidance on the conduct and reporting of systematic reviews in this area.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/952qk
 
Level of bias control achieved: Level 4. At least some of the data/evidence that will be used to answer the research question already exists AND is accessible in principle to the authors BUT the authors certify that they have not yet accessed any part of that data/evidence.
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Hunniford V. T., Montroy J., Fergusson D. A., Avey M. T., Wever K. E., McCann S. K., Foster M., Fox G., Lafreniere M., Ghaly M., Mannell S., Godwinska K., Gentles A., Selim S., MacNeil J., Sikora L., Sena E. S., Page M. J., Macleod M., Moher D., & Lalu M. M. (2021). Epidemiology and reporting characteristics of preclinical systematic reviews. PLOS Biology, 19:e3001177. https://doi.org/10.1371/journal.pbio.3001177
 
2. Wilson, E., Currie, G., Macleod, M., Kind, P. & Sena, E. S. (2023). Genetically-modified animals as models of neurodevelopmental conditions: an umbrella review, in principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/952qk
Genetically-modified animals as models of neurodevelopmental conditions: an umbrella reviewEmma Wilson; Gillian Currie; Malcolm Macleod; Peter Kind; Emily S Sena<p><strong>Objective</strong><br>Using genetically-modified animals to model neurodevelopmental conditions (NDCs) helps better our understanding of their underlying biology. In vivo research has unique characteristics not shared with clinical rese...Life SciencesChris Chambers2022-08-29 12:08:51 View
17 Nov 2022
STAGE 2
(Go to stage 1)

Removing barriers to plant-based diets: assisting doctors with vegan patients

Informing doctors of the evidence on plant-based diets

Recommended by ORCID_LOGO based on reviews by Alaa Aldoh, Joshua Tasoff and Bence Palfi
What the best diet is has always been an area of contention. But one thing is clear: Meat is not necessary for health or fitness, and a diet high in plant proteins may well be especially healthy (e.g. Herpich et al., 2022). Further, plant- rather than animal-based diets leave a lower carbon footprint. So what might hold people back from adopting a plant-based diet? One reason is that people may understandably approach their doctor for advice; and the doctor may advise against it, given that many doctors are not well trained in nutrition (Crowley et al., 2019).

Espinosa et al. (2022) conducted a randomised control trial on French general practitioners with 200 doctors given a leaflet and access to an online platform, and 200 controls. The information in the materials concerned the health benefits of plant-based diets, and what nutrients (e.g. B12) may be deficient and what may not be. Attitudes towards and knowledge about plant-based diets was assessed. On a scale of 0-100% expressing whether they would advise for or against (0 = not at all, 100 = absolutely), the intervention shifted attitudes making them more positive about plant based diets by 17 percentage points. However, knowledge of specifically what is worth testing for (e.g. is zinc deficiency more probable or not?) did not change much. The research shows just what can be achieved by a small leaflet (shifting attitudes) and what may require more extensive training (knowledge of relevant medical practice).

The Stage 2 manuscript was evaluated over one round of in-depth review. Based on the responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/fc9gp
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question existed prior to Stage 1 in-principle acceptance.
 
List of eligible PCI RR-friendly journals:
 

References

1. Crowley, J., Ball, L. & Hiddink, G. J. (2019.) Nutrition in medical education: a systematic review. Lancet Planetary Health. 3, e379–e389. https://doi.org/10.1016/S2542-5196(19)30171-8
 
2. Herpich, C., Müller-Werdan, U., & Norman, K. (2022). Role of plant-based diets in promoting health and longevity. Maturitas, 165, 47-51. https://doi.org/10.1016/j.maturitas.2022.07.003
 
3. Espinosa, R., Arpinon, T., Maginot, P., Demange, S. & Peureux, F. (2022). Removing barriers to plant-based diets: assisting doctors with vegan patients, acceptance of Version 2 by Peer Community in Registered Reports. https://osf.io/kq6eh?view_only=66eab29c7acb4aebbcec4631cbcb9217
Removing barriers to plant-based diets: assisting doctors with vegan patientsRomain Espinosa, Thibaut Arpinon, Paco Maginot, Sébastien Demange, and Florimond Peureux<p>Shifting to plant-based diets can alleviate many of the externalities associated with the current food<br>system. Spontaneous shifts in diet are often hindered by consumers’ imperfect knowledge about the<br>health risks and benefits, which lead...Medical Sciences, Social sciencesZoltan Dienes2022-08-27 11:01:32 View