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IdTitle * Authors * Abstract * PictureThematic fields * RecommenderReviewersSubmission date
05 Jun 2024
STAGE 1
article picture

Dose-response of tDCS effects on motor learning and cortical excitability: a preregistered study

How stimulation intensity affects motor learning

Recommended by ORCID_LOGO based on reviews by Charlotte Wiltshire and 1 anonymous reviewer
In neurostimulation research, the parameters of a stimulation protocol crucially impact on the effects of the stimulation. Transcranial direct current stimulation (tDCS) is a neurostimulation technique that typically uses current intensities about 1-2 mA in human research to modulate motor and cognitive behavior. The current sham-controlled study by Hsu et al. (2024) applies current intensities not only of 2 mA but also of 4 mA and 6 mA and thus extends our understanding of stimulation parameters while ethical standards are preserved.
 
The influence of tDCS over the primary motor cortex will be evaluated for neural plasticity during motor learning. Stimulation effects will be tested not only behaviorally but also physiologically by motor evoked potentials elicited by transcranial magnetic stimulation (TMS). The presented pilot data are promising and underline the feasibility of the proposed research design. The study will contribute to tDCS research by uncovering reasons for controversial findings and thus increase reproducibility.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/jyuev
 
Level of bias control achieved: Level 2. At least some data/evidence that will be used to answer the research question has been accessed and partially observed by the authors, but the authors certify that they have not yet observed the key variables within the data that will be used to answer the research question.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Hsu, G., Edwards, D. J., Cohen, L. G., & Parra, L. C. (2024). Dose-response of tDCS effects on motor learning and cortical excitability: a preregistered study. In principle acceptance of Version 1.3 by Peer Community in Registered Reports. https://osf.io/jyuev
Dose-response of tDCS effects on motor learning and cortical excitability: a preregistered studyGavin Hsu, Dylan J. Edwards, Leonardo G. Cohen, Lucas C. Parra<p>Neuromodulatory effects of transcranial direct current stimulation (tDCS) on the primary motor cortex (M1) have been reported in terms of changes in corticospinal excitability using motor evoked potentials (MEPs), as well as behavioral effects ...Engineering, Life SciencesChristina Artemenko2024-01-11 00:11:23 View
04 Dec 2023
STAGE 1

Cerebral laterality as assessed by functional transcranial Doppler ultrasound in left-and right-handers: A comparison between handwriting and writing using a smartphone

Does typing on a smartphone involve the same neural mechanisms as writing by hand?

Recommended by ORCID_LOGO based on reviews by Todd Richards and Dorothy Bishop
Language production is associated with a distinct lateralised pattern of brain activation biased toward the left cerebral hemisphere. This also applies to writing. It has also been shown to be modulated by handedness, with less pronounced lateralisation in left-handers. However, in recent decades the use of handwriting has declined significantly while the use of smartphones has exploded. To date, no study has explored whether the same neural correlates of written language production found for handwriting also hold for typing on a smartphone.
 
In the current study, Samsouris et al. (2023) will use functional transcranial Doppler ultrasound (fTCD) to measure blood flow velocity within cerebral hemispheres to investigate this question. This technique is particularly suited for this purpose because it provides better control for the movement confounds associated with a writing task and the technical challenges of using a smart device than other neuroimaging techniques like fMRI or M/EEG. The authors hypothesise that there will be no difference in left cerebral lateralisation for handwriting and typing on a smartphone. They also expect to replicate previous findings of weaker lateralisation in left-handers in written language production when typing on a smartphone. To isolate the effect of written language production, both these conditions will be corrected for their corresponding motor component using control conditions without a linguistic component.
 
The Stage 1 manuscript was evaluated over 6 rounds of in-depth review by the recommender and two expert reviewers, before issuing in-principle acceptance.
 
URL to the preregistered Stage 1 protocol: https://osf.io/j7egz
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Samsouris, C., Badcock, N. A., Vlachos, F., & Papadatou-Pastou, M. (2023). Cerebral laterality as assessed by functional transcranial Doppler ultrasound in left-and right-handers: A comparison between handwriting and writing using a smartphone. In principle acceptance of Version 7 by Peer Community in Registered Reports. https://osf.io/j7egz
Cerebral laterality as assessed by functional transcranial Doppler ultrasound in left-and right-handers: A comparison between handwriting and writing using a smartphoneChristos Samsouris, Nicholas A. Badcock, Filippos Vlachos, Marietta Papadatou-Pastou<p>Neuroscientific studies of traditional handwriting have revealed a left cerebral lateralization pattern for written language production, with distinct patterns between left- and right-handers. However, no study to date has investigated the cere...Life Sciences, Social sciencesD. Samuel Schwarzkopf2022-11-01 10:27:39 View
21 Oct 2022
STAGE 1

Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report

Testing the facilitatory effect of high-frequency transcranial random noise stimulation through enhancement of global motion processing

Recommended by ORCID_LOGO based on reviews by Sam Westwood and Filippo Ghin
High frequency transcranial random noise stimulation (hf-tRNS) is a relatively novel form of non-invasive brain stimulation, thought to enhance neural excitability and facilitate processing in targeted brain areas. The evidence for the efficacy of hf-tRNS is mixed, so a high-powered test of the proposed facilitatory effects would be of value to the field. This Registered Report will target the human middle temporal complex (hMT+), an area with a well-established critical role in global motion processing. The protocol is adapted from a study by Ghin and colleagues (2018) but focusing on a sub-set of the original experimental conditions and using a fully within-subjects design (n=42). Global motion processing will be operationalised in terms of the coherence threshold for identification of the dominant direction of random-dot motion. The experiment will test the predicted facilitation of contralateral motion processing (reduced coherence threshold) during hf-tRNS to the left hMT+. The specificity of this effect will be tested by comparison to a sham stimulation control condition and an active stimulation control condition (left forehead). By targeting a brain area with a well-established critical role in behaviour, this study will provide important information about the replicability and specificity of the facilitatory effects of hf-tRNS.
 
Following two rounds of in-depth review, the recommender judged that the manuscript met the Stage 1 criteria and awarded in-principle acceptance (IPA).  
 
URL to the preregistered Stage 1 protocol: https://osf.io/bce7u
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
References
 
1. Ghin, F., Pavan, A., Contillo, A., & Mather, G. (2018). The effects of high-frequency transcranial random noise stimulation (hf-tRNS) on global motion processing: an equivalent noise approach. Brain Stimulation, 11, 1263–75.
 
2. Caroll, M. B., Edwards, G. & Baker, C. I. (2022). Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered report, in principle acceptance of Version 7 by Peer Community in Registered Reports. https://osf.io/bce7u
Replicating the facilitatory effects of transcranial random noise stimulation on motion processing: A registered reportMica B. Carroll*, Grace Edwards*, Chris I. Baker<p>Non-invasive brain stimulation (NIBS) techniques have the potential to demonstrate the causal impact of targeted brain regions on specific behaviors, and to regulate or facilitate behavior in clinical applications. Transcranial random noise sti...Life SciencesRobert McIntosh2022-06-02 21:25:02 View
21 Feb 2025
STAGE 2
(Go to stage 1)

Does learning more about others impact liking them?: Replication and extension Registered Report of Norton et al. (2007)’s Lure of Ambiguity

Revisiting ‘less is more’: A failure to replicate the association between increased knowing and decreased liking

Recommended by ORCID_LOGO based on reviews by Philipp Schoenegger and Zoltan Kekecs
Does knowing more about others necessarily lead to greater liking, or might it breed contempt, as suggested by Norton et al. (2007)? In the current study, Horsham et al. (2025) tried to replicate and extend that original question. Collecting data from a large sample of U.S. undergraduates and employing carefully revised designs reviewed at Stage 1, they replicated Norton et al.’s initial studies (1a, 1b, and 2) while also adding new measures. Their primary aim was to see if the “less is more” effect, where increased familiarity decreases liking, would hold under rigorous modern standards, including pre-registration and several open science practices.
 
Results indicated that people indeed believe they will like someone more if they know more about that person, replicating Norton et al.’s initial finding from Studies 1a and 1b. However, the association between greater knowledge and reduced liking, the core of the “less is more” claim, was not consistently observed. Instead, the data showed little evidence that accumulating information inevitably decreases liking. Moreover, an added examination of curiosity as a potential mediator revealed that although curiosity and liking are positively related, curiosity itself was not strongly contingent on the amount of knowledge participants had. These findings help clarify why previous literature has sometimes presented mixed outcomes, and they underline the distinction between what people predict will happen and what actually does happen in forming impressions of others.
 
Peer review involved thorough evaluations by experts. Following multiple revisions through Stages 1 and 2, the manuscript has been deemed a carefully executed Registered Report, providing transparent methods, open data, and full reproducibility. It adds nuance to discussions around how knowledge, familiarity, and curiosity jointly shape our interpersonal attitudes. On this basis, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.​
 
URL to the preregistered Stage 1 protocol: https://osf.io/7mc4y
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Norton, M. I., Frost, J. H., & Ariely, D. (2007). Less is more: The lure of ambiguity, or why familiarity breeds contempt. Journal of Personality and Social Psychology, 92, 97-105. https://doi.org/10.1037/0022-3514.92.1.97
 
2. Horsham, Z., Haydock-Symonds, A., Imada, H., Tai, H. C., Lau, W. L., Shum, T. L., Zeng, Y., Chow, K., & Feldman, G. (2025). Does learning more about others impact liking them?: Replication and extension Registered Report of Norton et al. (2007)’s Lure of Ambiguity [Stage 2]. Acceptance of Version 6 by Peer Community in Registered Reports.​ https://osf.io/ygkft
Does learning more about others impact liking them?: Replication and extension Registered Report of Norton et al. (2007)’s Lure of AmbiguityZöe Horsham, Ashleigh Haydock-Symonds, Hirotaka Imada, Hiu Ching Tai, Wing Lam Lau, Tsz Lui Shum, Yuqing Zeng, Hiu Tang Chow, Gilad Feldman<p>Norton et al. (2007) demonstrated a counterintuitive phenomenon that knowing other people better and/or having more information about them is associated with decreased liking. They summarized it as - ambiguity leads to liking, whereas familiari...Social sciencesYuki Yamada Zoltan Kekecs, Philipp Schoenegger2024-11-22 04:27:45 View
11 Apr 2024
STAGE 1

Does retrieval practice protect memory against stress? A meta-analysis [Stage 1 Registered Report]

Can retrieval practice prevent the negative impact of acute stress on memory performance?

Recommended by ORCID_LOGO based on reviews by Chris Hartgerink (they/them) and Adrien Fillon
There are a number of broad assumptions about memory which have penetrated societal understanding and mostly reflect supporting academic evidence e.g., that acute stress can compromise memory performance (Shields et al., 2017) and that practicing recalling critical information can help retain that knowledge (Moriera et al., 2019). The evidence base is less consistent when evaluating whether retrieval practice can protect against the negative effects of acute stress on memory, despite it being highly important for educators as to whether this specific strategy for supporting memorisation can be evidenced as especially effective under stressful conditions. A rigorous review of this mixed evidence base could provide the basis for developments in memory theory and research practice, with potential for direct educational applications.
 
Meta-analyses can play a critical role in furthering our understanding of complex cognitive mechanisms where the evidence base includes a wide range of methods, factors and effect size estimates. Furthermore, there is a lack of rigorous meta-analyses that prioritise open and reproducible processes (Topor et al., 2022) which help role-model good practice. In the current Registered Report, Mihaylova et al. (2024) have proposed a rigorous meta-analysis to systematically review and synthesise the evidence on the effects of retrieval practice for memory performance under acute stress. The work looks to be especially valuable for a) informing future research directions through a structured risk of bias evaluation, and b) generating theoretical developments through a range of confirmatory moderators (including stressor types, memory strategies, time of delay and task type). The findings of the planned analyses are expected to be of immediate interest to educational and occupational domains where memory recall is a priority.
 
The Stage 1 manuscript was evaluated over two rounds of in-depth review. Based on detailed responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/pkrzb
 
Level of bias control achieved: Level 3. At least some data/evidence that will be used to the answer the research question has been previously accessed by the authors (e.g. downloaded or otherwise received), but the authors certify that they have not yet observed ANY part of the data/evidence.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Mihaylova, M., Kliegel, M, & Rothen, N. (2024). Does retrieval practice protect memory against stress? A meta-analysis. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/pkrzb
 
2. Moreira, B. F. T., Pinto, T. S. S., Starling, D. S. V., & Jaeger, A. (2019). Retrieval practice in classroom settings: A review of applied research. In Frontiers in Education (Vol. 4, p. 5). Frontiers Media SA. https://doi.org/10.3389/feduc.2019.00005 
 
3. Shields, G. S., Sazma, M. A., McCullough, A. M., & Yonelinas, A. P. (2017). The effects of acute stress on episodic memory: A meta-analysis and integrative review. Psychological Bulletin, 143, 636–675. https://doi.org/10.1037/bul0000100 
 
4. Topor, M. K., Pickering, J. S., Mendes, A. B., Bishop, D., Büttner, F., Elsherif, M. M., ... & Westwood, S. (2022). An integrative framework for planning and conducting Non-Intervention, Reproducible, and Open Systematic Reviews (NIRO-SR). Meta-Psychology. https://osf.io/preprints/metaarxiv/8gu5z
Does retrieval practice protect memory against stress? A meta-analysis [Stage 1 Registered Report]Mariela Mihaylova, Matthias Kliegel, Nicolas Rothen<p>[Note: This is a Stage 1 Registered Report. All placeholders will be replaced with actual results by Stage 2.]</p> <p><br>Stressors such as test anxiety (TA) are known to decrease memory retrieval, whereas retrieval practice (RP) is the phenom...Humanities, Social sciencesThomas Evans2023-02-16 14:39:06 View
28 Nov 2023
STAGE 1

One and only SNARC? A Registered Report on the SNARC Effect’s Range Dependency

Is the SNARC effect modulated by absolute number magnitude?

Recommended by ORCID_LOGO based on reviews by Melinda Mende and 1 anonymous reviewer
The Spatial-Numerical Association of Response Codes (SNARC) effect refers to the fact that smaller numbers receive faster responses with the left hand, and larger numbers with the right hand (Dehaene et al., 1993). This robust finding implies that numbers are associated with space, being represented on a mental number line that progresses from left to right. The SNARC effect is held to depend on relative number magnitude, with the mental number line dynamically adjusting to the numerical range used in a given context. This characterisation is based on significant effects of relative number magnitude, with no significant influence of absolute number magnitude. However, a failure to reject the null hypothesis, within the standard frequentist statistical framework, is not firm evidence for the absence of an effect. In this Stage 1 Registered Report, Roth and colleagues (2023) propose two experiments adapted from Dahaene’s (1993) original methods, with a Bayesian statistical approach to confirm—or rule out—a small effect (d = 0.15) of absolute number magnitude in modulating the classic SNARC effect.
 
The study plan was refined across two rounds of review, with input from two external reviewers and the recommender, after which it was judged to satisfy the Stage 1 criteria for in-principle acceptance (IPA).
 
URL to the preregistered Stage 1 protocol: https://osf.io/ae2c8
 
Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Dehaene, S., Bossini, S., & Giraux, P. (1993). The mental representation of parity and number magnitude. Journal of Experimental Psychology: General, 122(3), 371–396. https://doi.org/10.1037/0096-3445.122.3.371
 
Roth, L., Caffier, J., Reips, U.-D., Nuerk, H.-C., & Cipora, K. (2023). One and only SNARC? A Registered Report on the SNARC Effect’s Range Dependency. In principle acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/ae2c8
One and only SNARC? A Registered Report on the SNARC Effect’s Range DependencyLilly Roth, John Caffier, Ulf-Dietrich Reips, Hans-Christoph Nuerk, Krzysztof Cipora<p>Numbers are associated with space, but it is unclear how flexible these associations are. In this study, we will investigate whether the SNARC effect (Spatial-Numerical Association of Response Codes; Dehaene et al., 1993), which describes faste...Social sciencesRobert McIntosh2022-11-30 12:36:08 View
06 Sep 2024
STAGE 2
(Go to stage 1)

One and only SNARC? Spatial-Numerical Associations are not fully flexible and depend on both relative and absolute magnitude

A Registered Report demonstration that the SNARC effect depends on absolute as well as relative number magnitude

Recommended by ORCID_LOGO based on reviews by Claudia Gianelli
The Spatial-Numerical Association of Response Codes (SNARC) effect refers to the fact that smaller numbers receive faster responses with the left hand, and larger numbers with the right hand (Dehaene et al., 1993). This robust finding implies that numbers are associated with space, being represented on a mental number line that progresses from left to right. The SNARC effect is held to depend on relative number magnitude, with the mental number line dynamically adjusting to the numerical range used in a given context. This characterisation is based on significant effects of relative number magnitude, with no significant influence of absolute number magnitude. However, a failure to reject the null hypothesis is not firm evidence for the absence of an effect. In this Registered Report, Roth and colleagues (2024) report two large-sample online experiments, with a Bayesian statistical approach to confirm—or refute—a role for absolute number magnitude in modulating the classic SNARC effect (smallest effect size of interest, d = 0.15).
 
Experiment 1 closely followed Dehaene’s (1993) original methods, and found strong evidence for an influence of relative magnitude, and moderate-to-strong evidence against an influence of absolute magnitude. Experiment 2 was designed to exclude some potential confounds in the original method, and this second experiment found strong evidence for both relative and absolute magnitude effects, of comparable effect sizes (in the range of d = .24 to .42). This registered study demonstrates that the SNARC effect is not ‘fully flexible’, in the sense of depending only on relative number magnitude; it is also shaped by absolute magnitude.
 
This Stage 2 manuscript was evaluated by the recommender and one external reviewer. Following appropriate minor revisions, the recommender judged that the manuscript met the Stage 2 criteria for recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/ae2c8
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Dehaene, S., Bossini, S., & Giraux, P. (1993). The mental representation of parity and number magnitude. Journal of Experimental Psychology: General, 122, 371–396. https://doi.org/10.1037/0096-3445.122.3.371
 
2. Roth, L., Caffier, J., Reips, U.-D., Nuerk, H.-C., Overlander, A. T. & Cipora, K. (2023). One and only SNARC? Spatial-Numerical Associations are not fully flexible and depend on both relative and absolute magnitude [Stage 2]. Acceptance of Version 3 by Peer Community in Registered Reports. https://osf.io/epnd4
One and only SNARC? Spatial-Numerical Associations are not fully flexible and depend on both relative and absolute magnitudeLilly Roth, John Caffier, Ulf-Dietrich Reips, Hans-Christoph Nuerk, Annika Tave Overlander, Krzysztof Cipora<p>Numbers are associated with space, but it is unclear how flexible these associations are. We investigated whether the SNARC effect (Spatial-Numerical Association of Response Codes; Dehaene et al., 1993; i.e., faster responses to small/large num...Life SciencesRobert McIntosh2024-06-10 15:00:30 View
23 Mar 2023
STAGE 2
(Go to stage 1)

Revisiting the links between numeracy and decision making: Replication Registered Report of Peters et al. (2006) with an extension examining confidence

Assessing the replicability of specific links between numeracy and decision-making

Recommended by ORCID_LOGO based on reviews by Elena Rusconi
Numeracy – the ability to understand and work with numbers – is associated with a wide range of social and health-related outcomes, including socioeconomic status, employment, literacy, reasoning, and life satisfaction. A substantial body of evidence has also shown links between numeracy and decision-making, prompting the question of how it relates to finer-grained measures of reasoning, judgment and affect/emotion.
 
In the current study, Zhu and Feldman repeated four influential experiments from a study by Peters et al. (2006), which reported links between numeracy and performance on a variety of decision-making tasks, including attribute framing, frequency-percentage framing, susceptibility to affective influences, and various cognitive biases. The authors also explored several extended questions, including refinements of the original hypotheses and an examination of the relationship between numeracy and confidence in numeric judgments (subjective numeracy).
 
The results broadly constitute a successful replication, with higher numeracy associated with weaker attribute framing and susceptibility to bias. The relationship between numeracy and the frequency-percentage framing effect – that is, the change in decision-making when numbers are presented as frequencies (e.g. 5 out of 100) rather than percentages (e.g. 5%) – was inconclusive for the main analysis that treated numeracy as a categorical variable (low vs. high); however the link emerged reliably in exploratory analyses that considered numeracy as a continuous variable. The outcomes of the extended analyses were mixed, revealing evidence for a potentially weak relationship between numeracy and confidence.
 
The Stage 2 manuscript was evaluated over one round of in-depth review. Based on detailed responses to the reviewer's comments, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/r73fb
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA. 
 
List of eligible PCI RR-friendly journals:
 
 
References
 
1. Zhu, M. & Feldman, G. (2022). Revisiting the links between numeracy and decision making: Replication Registered Report of Peters et al. (2006) with an extension examining confidence. Acceptance of Version 5 by Peer Community in Registered Reports. https://osf.io/62wqb
 
2. Peters, E., Västfjäll, D., Slovic, P., Mertz, C. K., Mazzocco, K., & Dickert, S. (2006). Numeracy and decision making. Psychological Science, 17, 407-413. https://doi.org/10.1111%2Fj.1467-9280.2006.01720.x
Revisiting the links between numeracy and decision making: Replication Registered Report of Peters et al. (2006) with an extension examining confidenceMinrui Zhu, Gilad Feldman<p>Numeracy is individuals’ capacity to understand and process basic probability and numerical information required to make decisions. We conducted a Replication Registered Report of Peters et al. (2006) examining numeracy as a predictor of positi...Social sciencesChris Chambers2023-01-16 10:34:09 View
25 Jan 2022
STAGE 1

To help or hinder: Do the labels and models used to describe problematic substance use influence public stigma?

Understanding the role of health condition, aetiological labels, and attributional judgements in public stigma toward problematic substance use

Recommended by ORCID_LOGO based on reviews by Nicholas Sinclair-House and Roger Giner-Sorolla

People suffering from substance misuse problems are often stigmatised. Such public stigma may impair such people obtaining help and the quality of help that they receive. For this reason, previous research has investigated the factors that may reduce stigma. Evidence has been found, but not consistently, for the claim that labelling the condition as "chronically relapsing brain disease" vs a "problem" reduces stigma; as does "a health concern" vs " drug use". Another potentially relevant difference that may explain different previous results is describing how effective treatment can be.

In this Stage 1 Registered Report, Pennington et al. (2022) describe how they will investigate if any of these factors affect two different measures of stigma used in previous work, with a study well powered for testing whether the 99% CI lies outside or inside an equivalence region. While the CI being outside the region will straightforwardly justify concluding an effect of interest, a CI within the region will need to be interpreted with due regard to the fact that some effects within the region may be interesting.

The Stage 1 manuscript was evaluated over two rounds of review (including one round of in-depth specialist review). Based on comprehensive responses to the reviewers' comments, the recommender judged that the manuscript met the Stage 1 criteria and therefore awarded in-principle acceptance (IPA).

URL to the preregistered Stage 1 protocol: https://osf.io/4vscg

Level of bias control achieved: Level 6. No part of the data or evidence that will be used to answer the research question yet exists and no part will be generated until after IPA.

List of eligible PCI RR-friendly journals:

References

Pennington, C. R., Monk, R. L., Heim, D., Rose, A. K., Gough, T., Clarke, R., Knibb, G.,  & Jones, A. (2022). To help or hinder: Do the labels and models used to describe problematic substance use influence public stigma? Stage 1 preregistration, in principle acceptance of version 2 by Peer Community in Registered Reports. https://osf.io/4vscg

To help or hinder: Do the labels and models used to describe problematic substance use influence public stigma?Charlotte R. Pennington, Rebecca L. Monk, Derek Heim, Abi K. Rose, Thomas Gough, Ross Clarke, Graeme Knibb, and Andrew Jones.<p>Objectives: Problematic substance use is one of the most stigmatised health conditions, leading research to examine how the labels and models used to describe it influence public stigma. Two recent studies examine whether beliefs in a disease m...Social sciencesZoltan Dienes2021-10-28 13:26:28 View
10 Feb 2023
STAGE 2
(Go to stage 1)

The labels and models used to describe problematic substance use impact discrete elements of stigma: A Registered Report

Different ways of describing problematic substance use and its treatment influence public stigma

Recommended by ORCID_LOGO based on reviews by Nicholas Sinclair-House
People experiencing problematic substance use are often stigmatised by the general public. This public stigma may impair such people obtaining help and the quality of help that they receive. For this reason, previous research has investigated the factors that may exacerbate or lessen stigma by focusing on the terminology used to describe problematic substance use. However, the evidence is not clear cut, with some studies suggesting that labelling the condition as a "chronically relapsing brain disease" vs a "problem" reduces certain elements of stigma and other studies finding absence of evidence. A closer look at these studies points to methodological differences that may explain their results, such as whether problematic substance use is compared with another health condition, whether the individual is described as seeking treatment or not, and whether general or discrete elements of stigma are measured.
 
In this Stage 2 Registered Report, Pennington et al. (2023) isolated these methodological differences to investigate if any of them influenced two different measures of stigma used in previous work. They found that greater social distance, danger and public stigma but lower blame were ascribed to drug use relative to a health concern, supporting previous research to suggest that problematic substance use is a highly stigmatised health condition. Furthermore, greater (genetic) blame was reported when drug use was labelled as a ‘chronically relapsing brain disease’ relative to a ‘problem’. The results for attributional judgement were either inconclusive or statistically equivalent. In summary, these findings suggest that the labels and models used to describe problematic substance use may impact upon public stigma in distinct ways. The authors suggest that future research should justify which measures are being used in line with theory. They also put forward the notion that addiction is a functional attribution, which may explain the mixed literature on the brain disease model of addiction to date.
 
The Stage 2 manuscript was evaluated over one round of specialist review and several rounds of discussion with the recommender. Based on comprehensive responses, the recommender judged that the manuscript met the Stage 2 criteria and awarded a positive recommendation.
 
URL to the preregistered Stage 1 protocol: https://osf.io/4vscg
 
Level of bias control achieved: Level 6. No part of the data or evidence that was used to answer the research question was generated until after IPA.
 
List of eligible PCI RR-friendly journals:
 
 
References
 
Pennington, C. R., Monk, R. L., Heim, D., Rose, A. K., Gough, T., Clarke, R., Knibb, G., Patel, R., Rai, P., Ravat, H., Ali, R., Anastasiou, G., Asgari, F., Bate, E., Bourke, T., Boyles, J., Campbell, A., Fowler, N., Hester, S., Neil, C., McIntrye, B., Ogilvy, E., Renouf, A., Stafford, J., Toothill, K., Wong, H. K., &  Jones, A. (2023). The labels and models used to describe problematic substance use impact discrete elements of stigma: A Registered Report. Stage 2 acceptance of Version 4 by Peer Community in Registered Reports. https://osf.io/z9bnf
The labels and models used to describe problematic substance use impact discrete elements of stigma: A Registered ReportCharlotte R. Pennington, Rebecca L. Monk, Derek Heim, Abi K. Rose, Thomas Gough, Ross Clarke, Graham Knibb, Roshni Patel, Priya Rai, Halimah Ravat, Ramsha Ali, Georgiana Anastasiou, Fatemeh Asgari, Eve Bate, Tara Bourke, Jayme Boyles, Alix Campbel...<p>Objectives: Problematic substance use is one of the most stigmatised health conditions leading research to examine how the labels and models used to describe it influence public stigma. Two recent studies examine whether beliefs in a disease mo...Social sciencesZoltan Dienes2022-10-21 16:13:49 View